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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Crocin Advance Tablet:
Co-administration of Crocin Advance Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Crocin Advance Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Crocin Advance Tablet:
Co-administration of Teriflunomide with Crocin Advance Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Crocin Advance Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Crocin Advance Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Crocin Advance Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Lomitapide and Crocin Advance Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Crocin Advance Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crocin Advance Tablet:
Co-administration of ketamine and Crocin Advance Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Crocin Advance Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crocin Advance Tablet:
Co-administration of Crocin Advance Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Crocin Advance Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Mipomersen with Crocin Advance Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Crocin Advance Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Crocin Advance Tablet:
Co-administration of Crocin Advance Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Crocin Advance Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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PARACETAMOL-500MGMental and behavioural disorders due to use of alcohol
Severe
PARACETAMOL-500MGHepatic failure, not elsewhere classified
Severe

Drug-Diseases Interactions

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PARACETAMOL-500MGMental and behavioural disorders due to use of alcohol
Severe
How does the disease interact with Crocin Advance Tablet:
Chronic alcoholics may have a higher risk of hepatotoxicity when using Crocin Advance Tablet. Patients using Crocin Advance Tablet may cause severe liver damage, including acute liver failure that required a liver transplant and resulted in death.

How to manage the interaction:
Crocin Advance Tablet should be used with caution in patients who consume three or more alcoholic drinks a day. Avoid alcohol consumption while taking Crocin Advance Tablet. If you have nausea, vomiting, fever, rash, anorexia (eating disorder), over-tiredness, upper right stomach pain, dark urine, and jaundice, contact your doctor as these may be signs and symptoms of liver injury.
PARACETAMOL-500MGHepatic failure, not elsewhere classified
Severe
How does the disease interact with Crocin Advance Tablet:
The liver predominantly converts Crocin Advance Tablet to inactive forms. Patients with hepatic impairment may be more prone to toxicity because their minor metabolic pathways are more active.

How to manage the interaction:
Crocin Advance Tablet should be used with caution in patients with kidney insufficiency. Also, it is recommended to avoid drinking alcohol while taking Crocin Advance Tablet.
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Crocin Advance Tablet Substitute

Always consult your doctor before taking any new medications and supplements

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Side effects of Crocin Advance Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

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Side Effects

Common Side Effects
  • Nausea
  • Vomiting
  • Increased Aspartate Aminotransferase (AST) In Blood
  • Stomach Pain
  • Anemia
  • Rash
  • Shortness Of Breath

Consult you doctor in case you face the following side effects
  • Bleeding After Surgery
  • High Blood Pressure
  • High Blood Sugar
  • Accumulation Of Fluid Around Lungs

If any of the above side effects continue or intensify, seek medical advice. Professional guidance may be necessary for appropriate care and treatment adjustments.
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