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शराब
Caution
Pefpo 100mg Tablet का उपयोग करते समय शराब के सेवन से बचना/सीमित करना बेहतर है। अधिक जानकारी के लिए, कृपया चिकित्सकीय सलाह लें।
गर्भावस्था
Caution
यदि आप गर्भवती हैं तो कृपया अपने डॉक्टर से परामर्श करें, आपका डॉक्टर केवल तभी दवा लिखेगा जब लाभ जोखिम से अधिक हो।
स्तनपान
Caution
स्तनपान कराने वाली मां द्वारा उपयोग किए जाने पर सेफपोडोक्साइम प्रोक्सेटिल स्तन के दूध में जा सकता है। यदि आप स्तनपान करा रही हैं तो कृपया Pefpo 100mg Tablet शुरू करने से पहले अपने डॉक्टर से परामर्श करें।
ड्राइविंग
Caution
Pefpo 100mg Tablet से चक्कर आ सकता है, यदि आपको चक्कर आ रहा हो तो वाहन न चलाएं या भारी मशीनरी का संचालन न करें।
जिगर
Caution
खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको इस बारे में कोई चिंता है या यदि आपको लिवर की क्षति/लिवर की बीमारी है तो कृपया Pefpo 100mg Tablet लेने से पहले अपने डॉक्टर से परामर्श करें।
किडनी
Caution
खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको इस बारे में कोई चिंता है या यदि आपको किडनी की दुर्बलता/गुर्दे की बीमारी है तो कृपया Pefpo 100mg Tablet लेने से पहले अपने डॉक्टर से परामर्श करें।
बच्चे
Caution
Pefpo 100mg Tablet का उपयोग बच्चों के लिए केवल तभी किया जाना चाहिए जब डॉक्टर द्वारा निर्धारित किया गया हो। हालाँकि, Pefpo 100mg Tablet की 2 महीने से कम उम्र के बच्चों के लिए अनुशंसा नहीं की जाती है क्योंकि सुरक्षा और प्रभावकारिता स्थापित नहीं की गई है।
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Drug-Drug Interactions
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Co-administration of Pefpo 100mg Tablet with Heparin may enhance the levels or effects of heparin by anticoagulation (preventing blood from clotting).
How to manage the interaction:
Although there is an interaction, Pefpo 100mg Tablet can be taken with Heparin if prescribed by the doctor. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
Co-administration of Pefpo 100mg Tablet with the Cholera vaccine may reduce the effectiveness of the vaccine.
How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Pefpo 100mg Tablet or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
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Drug-Diseases Interactions
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Almost all antibacterial medications have been associated to reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent offenders.
How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in certain situations, as metabolites as well. In individuals with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise and their half-lives may be prolonged. According to the particular product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during extended and/or high-dose therapy since these medicines have occasionally been linked to nephrotoxicity and changes in renal function.
How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised.
Certain cephalosporins have been associated with cases of hepatitis. There has also been a brief increase in the levels of AST, ALT, and alkaline phosphatase. Patients with hepatic problems should be treated with caution and under close observation when using these medications.
How to manage the interaction:
Caution and monitoring is recommended in patients with liver disorders.
It has been suggested that cephalosporins can cause seizures. In particular in patients with a history of epilepsy and/or where prescribed doses of cephalosporins were exceeded because of renal impairment, cephalosporins have been associated with nonconvulsive status epilepticus (NCSE), encephalopathy, coma, asterixis, neuromuscular excitability, and myoclonia. Depending on the creatinine clearance, change the dosage. In individuals with known seizure disorders, anticonvulsant medication should be maintained. Patients should get a neurological exam to see if medication should be stopped if CNS side effects like seizures happen.
How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Dose adjustment may be needed.
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