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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

PENICILLAMINE-250MG

Manufacturer/Marketer :

RR Biotech

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHELATING AGENTS

Country of origin

India

Manufacturer/Marketer address

Nh 21 A, Dattowal, Nalagarh Dist Solan, Himachal Pradesh-174101
Other Info - AAR0019

Author Details

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FAQs

Aaramine-250mg Tablet works by blocking the action of certain chemical messengers that are responsible for inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.

Wilson’s disease is a condition where the body cannot get rid of copper properly and cause damage the liver, brain, and other organs. Aaramine-250mg Tablet contains penicillamine that works by helping the body to remove excess copper.

Avoid taking other medicines at the same time while taking Aaramine-250mg Tablet . If you take an iron supplement, take it at least 2 hours before or after you take Aaramine-250mg Tablet . Iron can make it harder for your body to absorb Aaramine-250mg Tablet . Avoid taking mineral supplements, unless your doctor advised you to. Do not drink milk within 1 hour before or after you take Aaramine-250mg Tablet . Do not take copper-containing foods like shellfish, chocolate, nuts, mushroom, and organ meats (liver pate, sweetbreads etc.)

Aaramine-250mg Tablet may cause side-effects such as protein in urine, low blood platelets, stomach upset or throwing up, diarrhea , change in taste, loss of appetite, mouth irritation, mouth sores. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

Aaramine-250mg Tablet should not be taken during pregnancy or if you are trying to become pregnant as Aaramine-250mg Tablet can cause birth defects, miscarriages or harm unborn babies. Avoid becoming pregnant for at least 6 months after stopping the treatment with Aaramine-250mg Tablet .

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Aaramine-250mg Tablet . It could lead to increased dizziness and drowsiness.

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Pregnancy

Unsafe

Aaramine-250mg Tablet is a pregnancy category D drug. It is not recommended to take Aaramine-250mg Tablet while you are pregnant. Aaramine-250mg Tablet may cause serious birth defects.

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Breast Feeding

Unsafe

Aaramine-250mg Tablet should not be used in breastfeeding mothers as Aaramine-250mg Tablet passes into breast milk.

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Driving

Caution

Aaramine-250mg Tablet may cause dizziness, drowsiness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Unsafe

Aaramine-250mg Tablet is not recommended for the liver patients.

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Kidney

Caution

Aaramine-250mg Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

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Children

Safe if prescribed

Aaramine-250mg Tablet should be used in children under the care of the doctor. The dose may depend on the weight and age of the child.

About Aaramine-250mg Tablet

Aaramine-250mg Tablet belongs to the group of medicines called ‘chelating agents’ used to treat severe rheumatoid arthritis, Wilsons disease, and cystinuria. Rheumatoid arthritis is a joint disorder in which our immune system attacks our body cells. Wilson disease is a genetic problem characterized by excess copper deposited in body parts like the eye, brain, and liver leading to metal toxicity. Cystinuria is the excess build-up of an amino acid called cystine in the urinary bladder and kidney, leading to harmful effects. 

Aaramine-250mg Tablet contains Penicillamine which works by blocking the action of certain chemical messengers responsible for inflammation and slows the progress of the condition with certain joint diseases. It works in Wilson's disease by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function, and mental, mood, and nerve problems (like confusion, and difficulty speaking or walking) caused due to Wilson's disease. Besides this, Aaramine-250mg Tablet is also used to treat cystinuria (kidney and bladder stone) and lead poisoning.

Take Aaramine-250mg Tablet exactly as prescribed by your doctor. You are advised to take Aaramine-250mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as protein in the urine, low blood platelets, stomach upset or throwing up, diarrhoea, change in taste, loss of appetite,  mouth irritation, and mouth sores. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Aaramine-250mg Tablet for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Aaramine-250mg Tablet if you are pregnant or planning for pregnancy as Aaramine-250mg Tablet causes serious congenital disabilities. Aaramine-250mg Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Your doctor may advise you to undergo regular blood tests, and kidney and liver tests to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Uses of Aaramine-250mg Tablet

Rheumatoid arthritis, Wilson's disease, Cystinuria, Lead poisoning

Medicinal Benefits Mweb

Medicinal Benefits

Aaramine-250mg Tablet contains Penicillamine primarily used to treat Wilson's disease (copper builds up in the body and may result in serious symptoms) and cystinuria (kidney stones). It is also used in combination with other treatments to treat severe rheumatoid arthritis. The treatment of rheumatoid arthritis Aaramine-250mg Tablet reduces pain, inflammation, and slow joint damage and disease progression over time; hence Aaramine-250mg Tablet is known as a disease-modifying anti-rheumatic drug (DMARD). In Wilson's disease, Aaramine-250mg Tablet works by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function and the mental, mood, and nerve problems (such as confusion, and difficulty speaking/walking) caused by Wilson's disease. In cystinuria, it helps decrease the amount of a certain substance (cystine) by binding to that substance which can cause kidney stones and prevent it from building up and forming stones. Besides this, Aaramine-250mg Tablet is also used to treat lead poisoning.

Directions for Use

Take Aaramine-250mg Tablet as advised by the doctor. Swallow it as a whole with a glass of water; do not break, or chew it.

Side Effects of Aaramine-250mg Tablet

  • Protein in urine
  • Low blood platelets
  • Stomach upset 
  • Diarrhoea
  • Change in taste
  • Loss of appetite
  • Mouth irritation
  • Mouth sores

Drug Warnings

Do not take Aaramine-250mg Tablet if you are allergic (hypersensitive) to penicillamine or any of the other ingredients in it. Inform your doctor if you have severe kidney problems, lupus erythematosus (an auto-immune disorder), agranulocytosis (a low white cell blood count), aplastic anaemia (symptoms including feeling tired, breathless, having pale skin and more susceptible to infection) or thrombocytopenia (a blood disorder which causes bleeding into your skin, bruising and bleeding more than normal). Do not take Aaramine-250mg Tablet if you are pregnant or planning to get pregnant and breastfeeding. This medicine may cause harm to the unborn baby if you take it while you are pregnant. Caution should be required while taking Aaramine-250mg Tablet by elderly patients as they may be at greater risk of suffering side effects if you are taking Aaramine-250mg Tablet over a long time, especially if you are on a restricted diet, as this medicine increases the requirement for pyridoxine (Vitamin B6) so your doctor may also prescribe this vitamin for you. If you are taking iron tablets, antacids, or digoxin (used to treat heart failure), please maintain two hours gap between these tablets and Aaramine-250mg Tablet . Low blood cell counts have happened while taking Aaramine-250mg Tablet . If blood cell counts get very low, this can lead to bleeding problems, infections, or anaemia, and sometimes, these have been deadly. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Aaramine-250 Tablet:
Deferiprone when taken with Aaramine-250 Tablet can cause an increased risk of low blood levels.

How to manage the interaction:
Co-administration of Aaramine-250 Tablet with Deferiprone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Aaramine-250 Tablet:
Taking Aaramine-250 Tablet and tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Aaramine-250 Tablet and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Aaramine-250 Tablet:
Taking cladribine with Aaramine-250 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Aaramine-250 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Aaramine-250 Tablet:
Using ioversol together with Aaramine-250 Tablet can cause an increased risk of kidney problems.

How to manage the interaction:
Although there is a drug interaction between Aaramine-250 Tablet and ioversol, they can be taken together if advised by the doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm consult your doctor immediately. Do not discontinue medications without consulting a doctor.
Severe
How does the drug interact with Aaramine-250 Tablet:
Using iodamide together with Aaramine-250 Tablet can cause an increased risk of kidney problems.

How to manage the interaction:
Although there is a drug interaction between Aaramine-250 Tablet and iodamide, they can be taken together if advised by the doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm consult your doctor immediately. Do not discontinue medications without consulting a doctor.
PenicillamineSodium aurothiomalate
Severe
How does the drug interact with Aaramine-250 Tablet:
Using Aaramine-250 Tablet together with sodium aurothiomalate can increase the severity of adverse effects of Aaramine-250 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Sodium aurothiomalate and Aaramine-250 Tablet, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Aaramine-250 Tablet:
Taking Aaramine-250 Tablet with Clozapine can increase the risk of low blood levels.

How to manage the interaction:
Taking Aaramine-250 Tablet with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PenicillamineMetrizamide
Severe
How does the drug interact with Aaramine-250 Tablet:
Taking Aaramine-250 Tablet together with metrizamide can cause severe kidney problems.

How to manage the interaction:
Although taking Aaramine-250 Tablet and Metrizamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Aaramine-250 Tablet:
Using Aaramine-250 Tablet with leflunomide can increase the risk of low blood levels.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Aaramine-250 Tablet, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Aaramine-250 Tablet:
Coadministration of Tenofovir disoproxil with Aaramine-250 Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Tenofovir disoproxil with Aaramine-250 Tablet can possibly result in an interaction, it can be taken when your doctor has advised it. However, if you experience vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • GOLD SODIUM THIOMALATE
  • DIGOXIN
  • ALUMINIUM HYDROXIDE
  • IBUPROFEN
  • INDOMETHACIN
  • NAPROXEN
  • OXYPHENBUTAZONE
  • PHENYLBUTAZONE
  • CHLOROQUINE
  • HYDROXYCHLOROQUINE
  • CLOZAPINE
  • LEVODOPA
  • AZATHIOPRINE
  • CYCLOPHOSPHAMIDE
  • MYCOPHENOLATE MOFETIL
  • CYCLOSPORINE
  • ZINC SULFATE
  • CARBONYL IRON
  • HEME IRON POLYPEPTIDE
  • AURANOFIN
  • AUROTHIOGLUCOSE
  • ZINC ACETATE
  • ZINC GLUCONATE

Habit Forming

No

Special Advise

  • Your doctor may advise you to take blood and urine tests while using Aaramine-250mg Tablet to examine your health condition and ensure that this medicine treats your condition.
  • People with Wilson disease should avoid using copper-containing foods like shellfish, nuts, chocolate, mushroom, and organ meats. 
  • Avoid using copper containers for drinking, cooking and eating. Ensure running water you drink should be reduced copper level up to the minimum. 
  • If you are using any nutritional supplements or herbal supplements which contains copper tell your doctor about this. Your doctor may suggest any other alternative to this. 

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Drink plenty of fluids.
  • Limit consumption of spinach, wheat bran, nuts, beets and dairy products.
  • Avoid high salt intake and foods containing baking soda.
  • Follow work safety regulations if you are at risk of occupational exposure. Wear necessary protective gear while working and do not take any contaminated material such as clothing or work gear to home. 
  • Avoid smoking and alcohol consumption.

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