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  3. ABCIXIREL 10MG INJECTION 5ML

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

ABCIXIMAB-2MG

Manufacturer/Marketer :

Reliance Life Sciences

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Country of origin

INDIA

Manufacturer/Marketer address

Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701
Other Info - ABC0025

FAQs

ABCIXIREL 10MG INJECTION contains Abciximab, which works by blocking the activity of glycoprotein IIb/IIIa receptor and thereby prevents platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation.

ABCIXIREL 10MG INJECTION is usually administered along with heparin and aspirin, so it might increase the risk of bleeding. Inform the doctor immediately if you notice excess bleeding.

ABCIXIREL 10MG INJECTION may cause anaemia (low haemoglobin and low red blood cell count). So, it would be best to include iron-rich food in your diet to prevent anaemia.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption. Consult your doctor for more information.

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Pregnancy

Caution

It is also unknown whether ABCIXIREL 10MG INJECTION can cause fetal damage or alter reproductive capacity when given to a pregnant woman. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Caution

Limited data are available on the effect of ABCIXIREL 10MG INJECTION on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving ABCIXIREL 10MG INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

ABCIXIREL 10MG INJECTION is used in PCI procedures in a hospital setting. Driving is not recommended.

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Liver

Caution

If you have liver problems, inform your doctor beforehand.

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Kidney

Unsafe

If you have kidney impairment, inform your doctor beforehand.

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Children

Unsafe

ABCIXIREL 10MG INJECTION is not recommended for use in children below 12 years of age, as efficacy and safety have not been established.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

About ABCIXIREL 10MG INJECTION

ABCIXIREL 10MG INJECTION belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. ABCIXIREL 10MG INJECTION is used as an adjunct during percutaneous coronary intervention (PCI) procedure in patients with unstable angina not responding to conventional medical therapy when PCI procedure is planned within 24 hours.

ABCIXIREL 10MG INJECTION contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. ABCIXIREL 10MG INJECTION results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST).

ABCIXIREL 10MG INJECTION may cause certain side effects such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, back pain, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer ABCIXIREL 10MG INJECTION. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

ABCIXIREL 10MG INJECTION should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, used dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. ABCIXIREL 10MG INJECTION is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving ABCIXIREL 10MG INJECTION, have/had a recent severe injury or surgery due to risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. ABCIXIREL 10MG INJECTION is not recommended for children below 12 years of age as efficacy and safety have not been established.

Uses of ABCIXIREL 10MG INJECTION

Myocardial infarction (heart attack)

Medicinal Benefits Mweb

Medicinal Benefits

ABCIXIREL 10MG INJECTION contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. ABCIXIREL 10MG INJECTION results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST). This medicine is always administered along with aspirin and heparin.

Directions for Use

A trained healthcare professional will administer ABCIXIREL 10MG INJECTION. Hence, do not self-administer.

Side Effects of ABCIXIREL 10MG INJECTION

  • Bleeding
  • Nausea
  • Headache
  • Abdominal pain
  • Hypotension
  • Vomiting
  • Dizziness
  • Back pain
  • Pain at the site of injection

Drug Warnings

Do not receive ABCIXIREL 10MG INJECTION if you are allergic to it. This medicine is contraindicated in patients having active internal bleeding, thrombocytopenia, recent major surgery or trauma, severe uncontrolled hypertension, history of cerebrovascular accident within two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, use of dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. ABCIXIREL 10MG INJECTION is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving ABCIXIREL 10MG INJECTION if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. ABCIXIREL 10MG INJECTION is not recommended for children below 12 years of age as efficacy and safety have not been established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Abcixirel 10mg Injection 5ml:
Co-administration of Abcixirel 10mg Injection 5ml and Rivaroxaban can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Abcixirel 10mg Injection 5ml and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Abcixirel 10mg Injection 5ml:
Co-administration of Abcixirel 10mg Injection 5ml with Cangrelor can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Cangrelor with Abcixirel 10mg Injection 5ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: difficulty with bleeding, complications, bruising, feeling dizzy or lightheaded, dark or sticky stools, intense headache, weakness, or bleeding or vomiting. Do not stop using any medications without talking to a doctor.
How does the drug interact with Abcixirel 10mg Injection 5ml:
Coadministration of Clopidogrel with Abcixirel 10mg Injection 5ml it increases the risk of bleeding.

How to manage the interaction:
Although there is a interaction between clopidogrel and Abcixirel 10mg Injection 5ml, but it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, and weakness. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Abcixirel 10mg Injection 5ml:
Coadministration of Abcixirel 10mg Injection 5ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Abcixirel 10mg Injection 5ml and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Abcixirel 10mg Injection 5ml:
When Ibrutinib and Abcixirel 10mg Injection 5ml are taken together, there is a chance that bleeding and haemorrhage risk or severity will rise.

How to manage the interaction:
Taking Abcixirel 10mg Injection 5ml with Ibrutinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Abcixirel 10mg Injection 5ml:
Taking Dabigatran etexilate with Abcixirel 10mg Injection 5ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Abcixirel 10mg Injection 5ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
AbciximabProtamine
Severe
How does the drug interact with Abcixirel 10mg Injection 5ml:
Coadministration of protamine and Abcixirel 10mg Injection 5ml can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Protamine with Abcixirel 10mg Injection 5ml can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Abcixirel 10mg Injection 5ml:
Using Nepafenac and Abcixirel 10mg Injection 5ml can interfere with clotting and cause bleeding, especially when used regularly or for prolonged periods.

How to manage the interaction:
Although taking Nepafenac and Abcixirel 10mg Injection 5ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood, severe headache, and weakness call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Abcixirel 10mg Injection 5ml:
Using Dasatinib together with Abcixirel 10mg Injection 5ml may increase the risk of bleeding.

How to manage the interaction:
Taking Abcixirel 10mg Injection 5ml with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away - bruising, feeling dizzy or lightheaded, dark stools, intense headaches. Do not stop using any medications without talking to a doctor.
How does the drug interact with Abcixirel 10mg Injection 5ml:
Co-administration of Abcixirel 10mg Injection 5ml with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Taking Prasugrel with Abcixirel 10mg Injection 5ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of the following symptoms: unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • CLOPIDOGREL
  • ENOXAPARIN
  • CAPTOPRIL
  • ENALAPRIL
  • NIFEDIPINE
  • CILNIDIPINE
  • ATENOLOL
  • SOTALOL
  • WARFARIN
  • HEPARIN

Habit Forming

No

Special Advise

  • Before administration of ABCIXIREL 10MG INJECTION, a blood test for platelet count, prothrombin time, ACT and APTT should be done to check for any hemostatic abnormalities.
  • As ABCIXIREL 10MG INJECTION will be administered along with heparin and aspirin, it is always important to check the patient for any bleeding conditions.

Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

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