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  1. Home
  2. Medicine

  3. Abirakast 250mg Tablet

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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
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COD available

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Abirakast 250mg Tablet, Pack of 1 Tablet
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Whats That

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Composition :

ABIRATERONE ACETATE-250MG

Manufacturer/Marketer :

Aprazer Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India
Other Info - AB59239

Author Details

Doctor imageDoctor badge

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:17 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Abirakast 250mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

No, do not stop taking Abirakast 250mg Tablet without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.

The common side-effects of Abirakast 250mg Tablet are nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain. These side effects usually do not require any medical attention.

Take Abirakast 250mg Tablet as advised by your doctor. However, if you forget or miss any dose of Abirakast 250mg Tablet, take it as soon as you remember unless it is time for your next dose. But do not double the dose.

Inform your doctor if you have a pre-existing or a history of liver/kidney disease, hypoglycemia, hypokalemia, bone disorders, adrenocortical insufficiency, fluid retention and cardiovascular conditions before taking Abirakast 250mg Tablet.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Interaction of Abirakast 250mg Tablet with alcohol is unknown. It is advisable to consult your doctor if you have concerns.

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Pregnancy

Not applicable

Not intended for women.

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Breast Feeding

Not applicable

Not intended for women.

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Driving

Caution

Abirakast 250mg Tablet may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery while taking Abirakast 250mg Tablet until your vision improves.

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Liver

Caution

Abirakast 250mg Tablet should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Abirakast 250mg Tablet should be used with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose based on your condition.

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Children

Unsafe

Abirakast 250mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established.

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Reference

  1. https://www.sterisindia.com/latest-update/abiraterone-acetate-/2822
  2. https://lotusinternational.com/product/zytiga/
  3. https://www.zytiga.com/
  4. https://medlineplus.gov/druginfo/meds/a611046.html
  5. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202379s031s033lbl.pdf

About Abirakast 250mg Tablet

Abirakast 250mg Tablet is an anti-androgen medicine used in the treatment of prostate cancer. It is used to treat metastatic castration-resistant prostate cancer (a condition where cancer does not get controlled with hormonal therapy) and metastatic castration-sensitive prostate cancer (a condition where cancer has spread to other parts of the body but can be controlled) in men. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc.

Abirakast 250mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Abirakast 250mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. 

Abirakast 250mg Tablet may cause certain side effects such as nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite and groin pain. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor. Take this medicine as advised by your doctor. It should be taken on an empty stomach at least 2 hours before or after meals. Your doctor will decide the dose of the medicine based on the severity of your disease.

Abirakast 250mg Tablet should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention before taking Abirakast 250mg Tablet. Abirakast 250mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. Inform your doctor of all your ongoing medications to avoid interactions. This medicine is used in combination with prednisolone for the treatment of prostate cancer. 

Uses of Abirakast 250mg Tablet

Prostate Cancer

Medicinal Benefits Mweb

Medicinal Benefits

Abirakast 250mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes increase of cancer cells in prostate gland. Abirakast 250mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. Abirakast 250mg Tablet is used in combination with prednisolone for the treatment of prostate cancer. It is mainly intended for use in men only.

Directions for Use

Abirakast 250mg Tablet should be taken on an empty stomach at least two hours before or after a meal. It is advised not to take more than the recommended dose of medicine. Swallow the medicine as a whole with a glass of water. Do not chew or crush or break the medicine.

Side Effects of Abirakast 250mg Tablet

  • Dizziness
  • Heartburn
  • Headache
  • Diarrhoea
  • Muscle Weakness
  • Joint Pain
  • Confusion
  • Hot Flushes
  • Loss of Appetite
  • Groin Pain

Drug Warnings

Abirakast 250mg Tablet should be avoided if you are allergic to it or any other components present in it. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention or taking any other medicines before taking Abirakast 250mg Tablet as it may cause serious side effects. Abirakast 250mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. This medicine is used in combination with prednisolone for the treatment of prostate cancer.

Drug-Drug Interactions

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AbirateroneZiprasidone
Critical
AbirateroneEliglustat
Critical

Drug-Drug Interactions

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AbirateroneZiprasidone
Critical
How does the drug interact with Abirakast 250mg Tablet:
Taking Abirakast 250mg Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Abirakast 250mg Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Abirakast 250mg Tablet:
Coadministration of Abirakast 250mg Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Abirakast 250mg Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneThioridazine
Critical
How does the drug interact with Abirakast 250mg Tablet:
Taking Abirakast 250mg Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirakast 250mg Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Abirakast 250mg Tablet:
Taking Abirakast 250mg Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Abirakast 250mg Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Abirakast 250mg Tablet:
Taking Abirakast 250mg Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirakast 250mg Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneArsenic trioxide
Severe
How does the drug interact with Abirakast 250mg Tablet:
Taking Abirakast 250mg Tablet with Arsenic trioxide can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Abirakast 250mg Tablet with arsenic trioxide together can result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneHydrocodone
Severe
How does the drug interact with Abirakast 250mg Tablet:
Coadministration of Abirakast 250mg Tablet with Hydrocodone can increase the levels of Hydrocodone in the body. This increases the risk or severity of side effects like low blood pressure, and low respiratory rate.

How to manage the interaction:
Taking Abirakast 250mg Tablet with Hydrocodone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, difficulty concentrating, impairment in thinking and judgment, fainting, confusion, excessive drowsiness, slow heart rate, and shallow or difficult breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneIbutilide
Severe
How does the drug interact with Abirakast 250mg Tablet:
Taking Abirakast 250mg Tablet with Ibutilide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirakast 250mg Tablet and Ibutilide together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneHydroxychloroquine
Severe
How does the drug interact with Abirakast 250mg Tablet:
The combined use of Abirakast 250mg Tablet and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Abirakast 250mg Tablet and Hydroxychloroquine can lead to an interaction, but it can be taken if your doctor advises. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
AbirateroneGatifloxacin
Severe
How does the drug interact with Abirakast 250mg Tablet:
Taking Abirakast 250mg Tablet with Gatifloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abirakast 250mg Tablet with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • PHENYTOIN
  • PHENOBARBITAL
  • FLECAINIDE
  • VENLAFAXINE

Habit Forming

No

Special Advise

  • Abirakast 250mg Tablet is not recommended for use in patients suffering from severe hepatotoxicity.
  • This medicine may cause the laboratory abnormalities like elevated alkaline phosphatase, hypercholesterolemia, hyperglycemia, and hypokalemia.
  • It is also advised to perform frequent checkups on your potassium, blood sugar, and blood pressure levels.

Diet & Lifestyle Advise

  • Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
  • It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
  • Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
  • Maintain a healthy weight by doing regular simple exercises and yoga. 
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
  • Avoid including red meat high amounts of meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Abirakast 250mg Tablet Substitute

Substitutes safety advice

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