Acetaclor Injection

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Acetaclor Injection

Written By Veda Maddala , M Pharmacy

Reviewed By Santoshini Reddy G , M Pharmacy

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About Acetaclor Injection

Acetaclor Injection belongs to a class of drugs called antidotes used to treat Paracetamol (acetaminophen) overdose and prevent liver injury. Paracetamol overdose may occur when the person takes more than 8 Paracetamol tablets in 24 hours accidentally or when intended to cause self-harm. If it is not treated promptly with an antidote, significant overdose can lead to liver failure.

Acetaclor Injection contains Acetylcysteine that works by restoring the levels of glutathione, a chemical that eliminates toxic substances.

Acetaclor Injection will be administered by a healthcare professional; do not self-administer. Some people may experience inflammation and pain at the injection site, nausea, vomiting, fever, excessive shivering, sweating, bruising, or bleeding more easily than normal. Most of these side effects of Acetaclor Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Acetaclor Injection or any other medicines, please tell your doctor. Acetaclor Injection is given to children in doses advised by a doctor based on the child’s age and weight. If you are pregnant or breastfeeding, please inform your doctor before taking Acetaclor Injection. If you are about to undergo any surgery, inform the anaesthetist or surgeon that you are being treated with Acetaclor Injection.

Uses of Acetaclor Injection

Paracetamol overdose

Therapeutic Class

[ANTIDOTES]

Medicinal Benefits

Key Benefits

Acetaclor Injection is an antidote for Paracetamol (acetaminophen) overdose. It works by restoring the body’s glutathione, a chemical that eliminates toxic substances. Also, it protects the liver from damage caused due to high levels of paracetamol. Acetaclor Injection is very effective when given within 10 hours of paracetamol overdose.

Directions for Use

Acetaclor Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Acetaclor Injection

Inflammation and pain at the injection site
Nausea
Vomiting
Fever
Excessive shivering
Sweating
Bruising or bleeding more easily than normal

Alcohol

Safe if prescribed

Interaction of alcohol with Acetaclor Injection is unknown. Please consult a doctor before consuming alcohol with Acetaclor Injection.

Pregnancy

Consult your doctor

Acetaclor Injection is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

Breast Feeding

Consult your doctor

Acetaclor Injection is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

Driving

Safe if prescribed

Acetaclor Injection usually does not affect your ability to drive or operate machinery.

Liver

Consult your doctor

Acetaclor Injection should be used with caution if you have a history of Liver diseases/conditions. Your doctor will decide to administer Acetaclor Injection if the benefits are greater than the risks.

Kidney

Consult your doctor

Acetaclor Injection should be used with caution if you have a history of Kidney diseases/conditions. Your doctor will decide to administer Acetaclor Injection if the benefits are greater than the risks.

Children

Safe if prescribed

Acetaclor Injection is given to children in doses advised by a doctor based on child’s age and weight.

Drug-Diseases Interactions

ACETYLCYSTEINE-20%W/VHepatic failure, not elsewhere classified

Severe

ACETYLCYSTEINE-20%W/VAsthma

Moderate

Drug-Diseases Interactions

ACETYLCYSTEINE-20%W/VHepatic failure, not elsewhere classified

Severe

How does the disease interact with Acetaclor Injection:
For individuals who have encephalopathy brought on by hepatic failure, the use of Acetaclor Injection should be stopped in order to prevent further nitrogenous material ingestion.

How to manage the interaction:
Acetaclor Injection should be discontinued in patients with encephalopathy (permanent or temporary brain damage) due to liver failure.

ACETYLCYSTEINE-20%W/VAsthma

Moderate

How does the disease interact with Acetaclor Injection:
When treating asthmatic patients or situations where bronchospasm has occurred in the past, Acetaclor Injection should be administered cautiously. When starting and continuing Acetaclor Injection medication, patients with asthma should be closely monitored.

How to manage the interaction:
Acetaclor Injection should be used with caution in asthma patients or where there is a history of bronchospasm (tightening of muscles lining airways). Asthma patients should be closely monitored during the initiation of and throughout Acetaclor Injection therapy.

ACETYLCYSTEINE-20%W/VOther disorders of fluid, electrolyte and acid-base balance

Moderate

How does the disease interact with Acetaclor Injection:
Acetaclor Injection administered intravenously may lead to fluid overload, which may result in hyponatremia, seizures, and even death.

How to manage the interaction:
To avoid fluid overload, a diluted dose is recommended, especially in patients less than 40 kg and those requiring fluid restrictions.

ACETYLCYSTEINE-20%W/VOther diseases of digestive system

Moderate

How does the disease interact with Acetaclor Injection:
Acetaclor Injection use may make vomiting worse. The risk of gastrointestinal haemorrhage should be assessed in patients with peptic ulcer disease.

How to manage the interaction:
Patients with peptic ulcer disease should be evaluated for the risk of gastrointestinal bleeding. In case of gastric haemorrhage, Acetaclor Injection is advised if your doctor considers benefit for you is greater than risk.

Drug Warnings

If you are allergic to Acetaclor Injection or any other medicines, please tell your doctor. Acetaclor Injection is given to children in doses advised by a doctor based on the child’s age and weight. If you are pregnant or breastfeeding, please inform your doctor before taking Acetaclor Injection. If you are about to undergo any surgery, inform the anaesthetist or surgeon/dentist that you are being treated with Acetaclor Injection. If you have a history of stomach ulcers or have asthma, inform your doctor before taking Acetaclor Injection.

Drug-Drug Interactions

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Habit Forming

Diet & Lifestyle Advise

Do not take more than the Paracetamol dose mentioned on the label or prescribed by the doctor.
Avoid giving Paracetamol to your child unless it is necessary for their fever or pain.
For children below 2 years, use Paracetamol only in the dose advised by the doctor based on the child’s body weight.
Limit or avoid alcohol consumption.

Special Advise

Acetaclor Injection may give a false positive result with reagent dipstick tests for urinary ketones. Therefore, inform the lab technician that you are taking Acetaclor Injection before undergoing any laboratory tests.

FAQs

How does Acetaclor Injection work?

Acetaclor Injection works by restoring the body’s glutathione, a chemical that eliminates toxic substances. Thus, it helps in the treatment of Paracetamol overdose.

I am due to undergo surgery. Should I inform the doctor that I have been treated with Acetaclor Injection?

You are recommended to inform your doctor or dentist that you have been treated with Acetaclor Injection if you are due to undergo any surgery or dental procedure because it may alter the effects of certain medicines that are used during anaesthesia.

Does Acetaclor Injection affect laboratory test results?

Acetaclor Injection may interfere with reagent dipstick tests for urinary ketones giving false positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Acetaclor Injection.

Does Acetaclor Injection cause allergic reactions?

Acetaclor Injection may cause allergic reactions in some people. It is not necessary for everyone taking Acetaclor Injection to have allergic reactions. However, if you notice a skin rash, itching, flushing, difficulty breathing or swelling of the face, inform your doctor immediately.

Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:46 AM IST

We provide you with authentic, trustworthy and relevant information

Reference

Country of origin

India

Other Info - AC77491

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