Acitinext-25 Capsule belongs to a group of medications called ‘retinoids’ used to treat psoriasis. Psoriasis is an autoimmune (immune system attacks healthy cells) skin disorder in which the skin becomes scaly, swollen, and itchy. It mostly affects the knee, elbows, scalp, and trunk. It is a lifelong condition, and treatment is given to remove affected skin cells and avoid flare-ups of the disease.

The Acitinext-25 Capsule contains ‘Acitretin’, which belongs to the class of retinoids derived from vitamin A. It has anti-inflammatory and antiproliferative (decreases skin cell multiplication) properties. It works by slowing down the progression of the disease. It reduces the speed of skin cell growth and gradually clears the affected skin. It helps reduce the redness, scaling, and thickness of psoriasis rashes.

Acitinext-25 Capsule is available in the form of tablets/capsules. You should take this medicine exactly as prescribed by your doctor. Acitinext-25 Capsule may cause side-effects such as dry lips, peeling of the skin, especially the palms of the hands and soles of the feet, nose bleed, scaling and thinning of healthy skin, reddening of the skin, itching, burning sensation on the skin, sticky skin, hair loss, swelling and pain in the area around your nails, fragile nails, inflammation of the eye (conjunctivitis), increased thirst, and feeling cold. These side effects usually go away after discontinuing the treatment. However, if any of these side effects persist or worsen, inform your doctor immediately.

Do not take Acitinext-25 Capsule if you are allergic to Acitretin or any other ingredients present in it. Acitinext-25 Capsule should not be used in patients with liver or kidney failure, high cholesterol, and taking other medicines containing retinoids or supplements containing vitamin A. Acitinext-25 Capsule should not be used in pregnant and breastfeeding women. Acitinext-25 Capsule should be used with caution in children as it may affect growth and bone development. Acitinext-25 Capsule may require dose adjustments when used in older people. Do not take alcohol, as it may increase the risk of side effects. Acitinext-25 Capsule may cause vision problems, especially in the dark, so do not drive or operate heavy machinery if you notice any vision problems.

Acitinext-25 Capsule contains ‘Acitretin’ that belongs to the class of ‘retinoids’. Retinoids are derived from vitamin A (retinol) and have anti-inflammatory and antiproliferative (reduces rapid skin cell division) action. Acitinext-25 Capsule works by slowing down the progression of the diseases. Acitinext-25 Capsule is used when the skin condition doesn’t improve with other conventional therapies. It can treat severe or extensive skin problems where the skin has become thick and scaly such as psoriasis. It can be long-term maintenance therapy for psoriasis patients. It can also be used in the treatment of other skin conditions such as ichthyosis (genetic skin disorder), pityriasis (skin rashes that appear as large spots on the chest, abdomen, or back), and lichen planus (itchy, non-infectious rashes on arms and legs).

Acitinext-25 Capsule should not be used in pregnant and breastfeeding women. So, the doctor may advise you to take a pregnancy test before using Acitinext-25 Capsule . You should also take effective and reliable contraception (such as an intrauterine device, contraceptive implant, or contraceptive pill and condom) during the treatment and after three years of discontinuing the treatment. You should take reliable contraception even if your periods are not regular or not sexually active unless your doctor decides that this is unnecessary. You should not donate blood during the treatment and after three years of discontinuing the treatment. Acitinext-25 Capsule should be used in caution in patients with diabetes as it can alter blood glucose levels. Acitinext-25 Capsule may cause vision problems, especially in the night-time. So, inform your doctor if you notice vision problems. Do not wear contact lenses during the treatment as the Acitinext-25 Capsule may cause dry eyes. Acitinext-25 Capsule may increase skin sensitivity, so avoid going in strong sunlight and using a sunbed. Acitinext-25 Capsule may affect your mood, so inform your doctor if you have mental health problems like depression. Also, inform your doctor if you notice drastic mood changes while using Acitinext-25 Capsule .

• Growth and bone development should be regularly monitored if the Acitinext-25 Capsule is given to children.
• Patients with diabetes are advised to monitor blood glucose levels while using this medicine regularly.
• Patients with high cholesterol should regularly monitor fat levels in the blood while using this medicine.
• Your doctor may also check liver function before, during, and after three weeks of discontinuing Acitinext-25 Capsule , as this medicine may affect liver function.
• If Acitinext-25 Capsule is prescribed for the long-term, your doctor may perform an x-ray of certain bones once a year, as this medicine may affect bone development.
• Acitinext-25 Capsule may cause birth defects, so women planning for pregnancy are advised to the regular pregnancy test and should not become pregnant for the next three years after using Acitinext-25 Capsule .