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Composition :
CLARITHROMYCIN-1%W/W
Manufacturer/Marketer :
Systopic Laboratories Pvt Ltd
Consume Type :
Topical
Expires on or after :
Return Policy :
Not Returnable
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Drug-Drug Interactions
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice
Drug-Drug Interactions
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Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
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Drug-Diseases Interactions
CLARITHROMYCIN-1%W/WOther bacterial intestinal infections
Severe
CLARITHROMYCIN-1%W/WToxic liver disease
Moderate
Drug-Diseases Interactions
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CLARITHROMYCIN-1%W/WOther bacterial intestinal infections
Severe
How does the disease interact with Acnesol-CL Gel 15 gm:
Almost all antibacterial medications have been associated with cases of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent those involved.
How to manage the interaction:
Anti-bacterial medicines may cause Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis. Therapy should be administered with caution in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile is advised.
Almost all antibacterial medications have been associated with cases of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent those involved.
How to manage the interaction:
Anti-bacterial medicines may cause Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis. Therapy should be administered with caution in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile is advised.
CLARITHROMYCIN-1%W/WToxic liver disease
Moderate
How does the disease interact with Acnesol-CL Gel 15 gm:
Patients on Acnesol-CL Gel 15 gm have been reported to experience hepatic dysfunction, including elevated liver enzymes, cholestatic and/or hepatocellular hepatitis, with or without jaundice. Using this medication to patients with hepatic impairment requires caution and close monitoring. If hepatitis signs and symptoms appear, treatment must be stopped.
How to manage the interaction:
Caution and monitoring is advised if Acnesol-CL Gel 15 gm is used in patients with liver impairment. Treatment must be discontinued immediately if signs and symptoms of hepatitis such as anorexia, jaundice, dark urine, pruritus, or tender abdomen occur. The use of Acnesol-CL Gel 15 gm is contraindicated in patients with a history of cholestatic jaundice or liver impairment associated with the prior use of Acnesol-CL Gel 15 gm.
Patients on Acnesol-CL Gel 15 gm have been reported to experience hepatic dysfunction, including elevated liver enzymes, cholestatic and/or hepatocellular hepatitis, with or without jaundice. Using this medication to patients with hepatic impairment requires caution and close monitoring. If hepatitis signs and symptoms appear, treatment must be stopped.
How to manage the interaction:
Caution and monitoring is advised if Acnesol-CL Gel 15 gm is used in patients with liver impairment. Treatment must be discontinued immediately if signs and symptoms of hepatitis such as anorexia, jaundice, dark urine, pruritus, or tender abdomen occur. The use of Acnesol-CL Gel 15 gm is contraindicated in patients with a history of cholestatic jaundice or liver impairment associated with the prior use of Acnesol-CL Gel 15 gm.
CLARITHROMYCIN-1%W/WOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Acnesol-CL Gel 15 gm:
The kidney and liver are the organs that eliminate of Acnesol-CL Gel 15 gm the most. In individuals with severe renal impairment (CrCl 30 mL/min), a lower dose or longer dosing intervals are advised. Patients with mild to moderate renal impairment often do not require dosage modifications, while medication accumulation may happen if there is concurrent liver illness. It is suggested to monitor.
How to manage the interaction:
Dose adjustment may be needed in patients with severe kidney impairment. Monitoring is advised in patients with mild to moderate kidney impairment.
The kidney and liver are the organs that eliminate of Acnesol-CL Gel 15 gm the most. In individuals with severe renal impairment (CrCl 30 mL/min), a lower dose or longer dosing intervals are advised. Patients with mild to moderate renal impairment often do not require dosage modifications, while medication accumulation may happen if there is concurrent liver illness. It is suggested to monitor.
How to manage the interaction:
Dose adjustment may be needed in patients with severe kidney impairment. Monitoring is advised in patients with mild to moderate kidney impairment.
CLARITHROMYCIN-1%W/WMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Acnesol-CL Gel 15 gm:
Myasthenia gravis symptoms have been observed to worsen and new myasthenic syndrome symptoms appear when macrolide antibiotics are used, according to reports. In patients who have a history of myasthenia gravis, therapy with these medicines should be used with caution.
How to manage the interaction:
Therapy should be administered cautiously in patients with a history of myasthenia gravis as the use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis.
Myasthenia gravis symptoms have been observed to worsen and new myasthenic syndrome symptoms appear when macrolide antibiotics are used, according to reports. In patients who have a history of myasthenia gravis, therapy with these medicines should be used with caution.
How to manage the interaction:
Therapy should be administered cautiously in patients with a history of myasthenia gravis as the use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis.
CLARITHROMYCIN-1%W/WAbnormal results of function studies
Moderate
How does the disease interact with Acnesol-CL Gel 15 gm:
Macrolides have been associated with an increase in the QT interval and occasional cases of arrhythmia. Patients with known QT interval prolongation, ventricular cardiac arrhythmia, including torsades de pointes, patients with proarrhythmic conditions like untreated hypokalemia or hypomagnesemia, clinically significant bradycardia, or patients taking other drugs that prolong the QT interval should avoid taking Acnesol-CL Gel 15 gm and erythromycin.
How to manage the interaction:
Acnesol-CL Gel 15 gm should be avoided in patients with known prolongation of the QT interval, abnormal heart rhythm, uncorrected low potassium or low magnesium, clinically significant slow heart rate, or receiving other drugs that prolong the QT interval.
Macrolides have been associated with an increase in the QT interval and occasional cases of arrhythmia. Patients with known QT interval prolongation, ventricular cardiac arrhythmia, including torsades de pointes, patients with proarrhythmic conditions like untreated hypokalemia or hypomagnesemia, clinically significant bradycardia, or patients taking other drugs that prolong the QT interval should avoid taking Acnesol-CL Gel 15 gm and erythromycin.
How to manage the interaction:
Acnesol-CL Gel 15 gm should be avoided in patients with known prolongation of the QT interval, abnormal heart rhythm, uncorrected low potassium or low magnesium, clinically significant slow heart rate, or receiving other drugs that prolong the QT interval.
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