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  1. Home
  2. Medicine

  3. Addperam 4 Tablet 10's

Addperam 4 Tablet 10's, Pack of 10 TabletS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
48 Hrs returnable
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COD available

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Whats That

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Composition :

PERAMPANEL-4MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICONVULSANT

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country Of Origin: India
Other Info - ADD0107

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:40 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Addperam 4 Tablet prevents seizures by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the abnormal and excessive activity of the nerve cells in the brain.

Addperam 4 Tablet may cause weight gain, so try to maintain a proper weight by following a healthy diet and exercising regularly.

Do not discontinue Addperam 4 Tablet without consulting your doctor. To treat your condition effectually, continue taking Addperam 4 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Addperam 4 Tablet ; your doctor will reduce the dose gradually to avoid precipitating seizures.

Avoid conceiving while on treatment with Addperam 4 Tablet as it is not recommended for use during pregnancy. Use a reliable method of contraception during treatment with Addperam 4 Tablet and for one month after the last dose of Addperam 4 Tablet .

Addperam 4 Tablet might make certain hormonal contraceptives, such as levonorgestrel less effective, affecting contraception. Therefore, you are advised to use other forms of contraception such as coil or condom while on treatment with Addperam 4 Tablet . Discuss with your doctor if you have any concerns.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Addperam 4 Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Addperam 4 Tablet is not recommended during pregnancy.

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Breast Feeding

Caution

It is not known if Addperam 4 Tablet passes into breast milk. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Unsafe

Addperam 4 Tablet causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Addperam 4 Tablet if you have a liver impairment or any concerns regarding this. Avoid taking Addperam 4 Tablet if you have serious liver problems.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Addperam 4 Tablet if you have kidney impairment or any concerns regarding this. Avoid taking Addperam 4 Tablet if you have moderate or serious kidney problems.

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Children

Caution

Addperam 4 Tablet is not recommended for children below four years. The safety and effectiveness have not been established in children below 4 years of age for partial seizures and below 7 years of age for generalised seizures.

Product Substitutes

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/202834s011lbl.pdf
  2. https://www.medicines.org.uk/emc/product/7874/smpc

About Addperam 4 Tablet

Addperam 4 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading unconscious state. 

Addperam 4 Tablet contains 'Perampanel'. It prevents seizures or epilepsy by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the brain's abnormal and excessive activity of the nerve cells.

In some cases, Addperam 4 Tablet may cause common side effects such as dizziness, drowsiness, increased or decreased appetite, weight gain, fatigue, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Addperam 4 Tablet is not recommended during pregnancy and in children below four years. Consult your doctor if you are breastfeeding. Addperam 4 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Addperam 4 Tablet as it could lead to increased dizziness and drowsiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Addperam 4 Tablet

Epilepsy/seizures

Medicinal Benefits Mweb

Medicinal Benefits

Addperam 4 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics. Addperam 4 Tablet contains perampanel. It is used to treat epilepsy. Addperam 4 Tablet prevents seizures or epilepsy by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the abnormal and excessive activity of the nerve cells in the brain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Addperam 4 Tablet

  • Dizziness
  • Drowsiness or sleepiness
  • Increased or decreased appetite
  • Weight gain
  • Feeling aggressive, angry, irritable, anxious or confused
  • Fatigue
  • Nausea

Drug Warnings

Do not take Addperam 4 Tablet if you are allergic to any of its contents. Inform your doctor before taking Addperam 4 Tablet if you have serious liver problems, moderate or severe kidney problems, alcoholism, or drug dependence. Addperam 4 Tablet is not recommended during pregnancy and in children below 4 years. Consult your doctor if you are breastfeeding. Addperam 4 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Addperam 4 Tablet as it could lead to increased dizziness and drowsiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions

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PerampanelEsketamine
Severe
PerampanelKetamine
Severe

Drug-Drug Interactions

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PerampanelEsketamine
Severe
How does the drug interact with Addperam 4 Tablet:
Co-administration of Addperam 4 Tablet with esketamine can increase the risk of side effects of Addperam 4 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Addperam 4 Tablet and Esketamine, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
PerampanelKetamine
Severe
How does the drug interact with Addperam 4 Tablet:
Using ketamine together with Addperam 4 Tablet may increase side effects such as dizziness, drowsiness, confusion and difficulty concentrating.

How to manage the interaction:
Although there is a possible interaction between Addperam 4 Tablet and Ketamine, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
PerampanelSodium oxybate
Severe
How does the drug interact with Addperam 4 Tablet:
Using sodium oxybate together with Addperam 4 Tablet may increase side effects such as dizziness, drowsiness, confusion, difficulty concentrating

How to manage the interaction:
Although taking Addperam 4 Tablet and Sodium oxybate together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without talking to your doctor.
PerampanelBuprenorphine
Severe
How does the drug interact with Addperam 4 Tablet:
When buprenorphine is used with Addperam 4 Tablet, it may lead to significant adverse effects.

How to manage the interaction:
Concomitant administration of buprenorphine alongside Addperam 4 Tablet can result in an interaction, it can be taken if a doctor has advised it. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Consult a doctor if you have any questions or concerns. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ESLICARBAZEPINE ACETATE
  • RUFINAMIDE
  • CLOBAZAM
  • TOPIRAMATE
  • BACLOFEN

Habit Forming

Yes

Special Advise

  • Close monitoring of lipid profile is recommended during treatment with Addperam 4 Tablet .
  • Consult your doctor immediately if you experience suicidal tendencies.

Diet & Lifestyle Advise

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Exercising regularly helps in maintaining weight and improving overall health.
  • Rest well, and get plenty of sleep.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Have a seizure response plan, and help those around you know what to do.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Avoid smoking and alcohol consumption.

Addperam 4 Tablet Substitute

Substitutes safety advice

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