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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

LENVATINIB-4MG

Manufacturer/Marketer :

Adley Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

2/236, KAMBRATH THAZAM, PULLALUR, KURUVATTOOR PO, NA KOZHIKODE Kozhikode Kerala 673012
Other Info - ADL0024

FAQs

Adlante 4 Capsule contains Lenvatinib, which works by inhibiting the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.

It is advised not to miss any dose of medicine. If you miss it, take the medicine as soon as you remember. However, if it is time for your next dose, avoid taking the missed dose and do not double the dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is unknown whether Adlante 4 Capsule interacts with alcohol. Consult your doctor.

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Pregnancy

Unsafe

Adlante 4 Capsule is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Adlante 4 Capsule . You should not become pregnant while you are taking Adlante 4 Capsule for at least 3o days from the last dose of Adlante 4 Capsule . Using effective birth control methods while on treatment with Adlante 4 Capsule is suggested.

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Breast Feeding

Unsafe

Inform your doctor if you are intending to breastfeed. Breastfeeding should be avoided while getting Adlante 4 Capsule and for one week from the final dosage of administration.

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Driving

Unsafe

Adlante 4 Capsule is known to cause dizziness and visual disturbances. Hence, avoid driving and operating machines until you are completely alert.

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Notify your doctor if you notice any of the following symptoms: yellowing of your skin or whites of your eyes, fleeing drowsy, abdominal pain, dark-coloured urine, easier bleeding or bruising than usual. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine.

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Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before taking Adlante 4 Capsule . It may cause kidney injury. Notify your doctor if you experience symptoms such as decreased urine output, blood in your urine, ankle edema, or lack of appetite.

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Children

Unsafe

Adlante 4 Capsule is not recommended for use in children, as the safety and efficacy have not been established.

About Adlante 4 Capsule

Adlante 4 Capsule is an anti-cancer medicine used in the treatment of various types of cancers. Cancer is a disease caused by the abnormal growth of cells that divide uncontrollably. This medicine is used in treating hepatocellular carcinoma as a first-line therapy, differentiated thyroid cancer in patients with locally recurrent or metastatic, progressive, radioactive iodine-refractory, advanced renal cell carcinoma in combination with pembrolizumab, and advanced endometrial cancer in combination with pembrolizumab.

Adlante 4 Capsule contains Lenvatinib, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.

Adlante 4 Capsule may cause certain side effects such as diarrhoea, decreased appetite, nausea, vomiting, tiredness, itching, rash, headache, cough, abdominal pain, hoarseness, and dizziness. Inform your doctor if any of these side effects bother you. Adlante 4 Capsule should be taken as prescribed by your doctor. Do not take more than the recommended dose of medicine.

If you are allergic to Adlante 4 Capsule or its components, inform your doctor. Before taking Adlante 4 Capsule , inform your doctor if you have/had liver or kidney disease, calcium deficiency, heart problems, increased blood pressure, seizures, bleeding disorders, vision problems, and a history of blood clots. This medicine is known to cause embryo-fetal toxicity. It is not recommended for use in pregnancy and breastfeeding. 

Uses of Adlante 4 Capsule

Renal Cell Carcinoma, Hepatocellular carcinoma, Differentiated thyroid cancer, Endometrial cancer.

Medicinal Benefits Mweb

Medicinal Benefits

Adlante 4 Capsule contains Lenvatinib, which is used in treating different types of cancer. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Adlante 4 Capsule stops the body's production, spread and growth of cancerous cells.

Directions for Use

Take Adlante 4 Capsule as prescribed by the doctor. It can be taken with or without food. Swallow it as a whole with a glass of water. Do not crush, break, or chew it. It is advised not to take more than the recommended dose of medicine.

Side Effects of Adlante 4 Capsule

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Tiredness
  • Muscle/joint pain
  • Dizziness
  • Weakness
  • Cough
  • Headache
  • Itching
  • Rash
  • Decreased weight
  • Abdominal pain
  • Vision problem

Drug Warnings

To treat your condition effectually, continue taking Adlante 4 Capsule for the period that your doctor has prescribed. Avoid taking Adlante 4 Capsule if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, any planned surgery, heart disease, stroke, blood or bleeding disorders, or gastrointestinal disorders. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children below 18 years of age as the safety and efficacy are not established. Adlante 4 Capsule may cause hypertension, thrombotic events, hemorrhagic events, hypothyroidism, gastrointestinal perforation and fistula, Reversible Posterior Leukoencephalopathy Syndrome (RPLS), elevated liver enzymes, kidney impairment, hypocalcemia, wound healing problems, and osteonecrosis in some patients. Hence, inform your doctor about your complete medication and medical history before taking Adlante 4 Capsule .

Drug-Drug Interactions

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LenvatinibHalofantrine
Critical
LenvatinibThioridazine
Critical

Drug-Drug Interactions

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LenvatinibHalofantrine
Critical
How does the drug interact with Adlante 4 Capsule:
Taking Adlante 4 Capsule and Halofantrine together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Adlante 4 Capsule and Halofantrine together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibThioridazine
Critical
How does the drug interact with Adlante 4 Capsule:
Taking Adlante 4 Capsule and Thioridazine together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Using Adlante 4 Capsule and Thioridazine is not recommended, but they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibPimozide
Critical
How does the drug interact with Adlante 4 Capsule:
Coadministration of Adlante 4 Capsule with Pimozide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although using Adlante 4 Capsule and Pimozide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibSaquinavir
Critical
How does the drug interact with Adlante 4 Capsule:
Taking Adlante 4 Capsule and Saquinavir together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Adlante 4 Capsule and Saquinavir together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibGrepafloxacin
Critical
How does the drug interact with Adlante 4 Capsule:
Coadministration of grepafloxacin and Adlante 4 Capsule can increase the risk irregular heart rhythm.

How to manage the interaction:
Although using Adlante 4 Capsule and Grepafloxacin together is not recommended as it can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
LenvatinibSparfloxacin
Critical
How does the drug interact with Adlante 4 Capsule:
Taking Adlante 4 Capsule and Sparfloxacin together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Using Adlante 4 Capsule and Sparfloxacin is not recommended, but they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibZiprasidone
Critical
How does the drug interact with Adlante 4 Capsule:
Taking Adlante 4 Capsule and Ziprasidone together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Adlante 4 Capsule and Ziprasidone together is not recomended as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
LenvatinibMesoridazine
Critical
How does the drug interact with Adlante 4 Capsule:
Taking Adlante 4 Capsule with Mesoridazine can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Adlante 4 Capsule and mesoridazine, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LenvatinibOsimertinib
Severe
How does the drug interact with Adlante 4 Capsule:
Using osimertinib together with Adlante 4 Capsule can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Adlante 4 Capsule and osimertinib, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LenvatinibRibociclib
Severe
How does the drug interact with Adlante 4 Capsule:
Taking Adlante 4 Capsule and Ribociclib together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Adlante 4 Capsule and Ribociclib together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience severe or prolonged diarrhea, vomiting, sudden dizziness, feeling lightheaded or fainting, shortness of breath, or heart palpitations, call your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ESCITALOPRAM
  • CITALOPRAM
  • EFAVIRENZ
  • TERIFLUNOMIDE
  • SPARFLOXACIN
  • MOXIFLOXACIN

Habit Forming

No

Special Advise

  • Your doctor may suggest periodic liver function tests, kidney function tests, lung function tests and urine tests to monitor the function of the liver, kidney, lungs and the presence of protein in urine due to the use of Adlante 4 Capsule .
  • Using contraceptive pills while using Adlante 4 Capsule to prevent pregnancy is advised.
  • Thyroid function and adrenocorticotropic hormone levels will be monitored during treatment to avoid any life-threatening side effects.
  • It is advised to use contraceptive pills while using Adlante 4 Capsule to prevent pregnancy.
  • Seek medical attention immediately if you have swelling in your lower legs, fast heartbeats, or trouble breathing, as it may be a sign of a heart problem.

Diet & Lifestyle Advise

  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight.

Adlante 4 Capsule Substitute

Substitutes safety advice
  • Lenvima 4 mg Capsule 10's

    by AYUR

    1118.15per tablet
  • Lenvatol 4 Capsule 10's

    by Others

    167.81per tablet
  • Lenvenib 4 mg Capsule 7's

    by Others

    157.50per tablet
  • Lenvat 4 Capsule 30's

    by Others

    82.00per tablet
  • Lentykine 4 mg Capsule 10's

    by AYUR

    135.00per tablet
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