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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

DOCETAXEL-20MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

Adley Formulation, Sco- 42, Sector 12, Panchkula-134112, Haryana, India
Other Info - ADO0010

Author Details

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FAQs

Adoxi 20mg Injection Combipack contains Docetaxel, an anti-neoplastic agent. It prevents the cancer cells from rapidly dividing and spreading, thus slowing down their growth.

Adoxi 20mg Injection Combipack should be used with caution and under doctor's supervision only if you have any medical history of any allergic reactions, liver or kidney diseases, non-small cell lung cancer, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions (excess fluid around lungs), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Let your doctor know if you have any other medical concerns before using Adoxi 20mg Injection Combipack .

During treatment with Adoxi 20mg Injection Combipack , it is essential to look for any signs of swelling (fluid retention/oedema), dizziness/fainting, difficulty in breathing, irregular heartbeat, swelling, pain and tenderness in the abdomen region, blood in stools, skin rashes, easy bleeding or bruising, sores in the mouth or throat or symptoms of infection like fever and sore throat. If you further notice any symptoms that are not manageable or unusual, please seek prompt medical attention.

It is advised to consult your doctor before undergoing any vaccination and take advice accordingly. Also, please avoid contact with people who have recently been vaccinated with the oral polio vaccine.

Docetaxel might cause serious allergic reactions and fluid retention if you had previously experienced allergic reactions with paclitaxel and cabazitaxel. These medicines contain polysorbate 80, an excipient. If you had any allergic reactions with medicines containing polysorbate 80, Adoxi 20mg Injection Combipack is not recommended. Please consult your doctor for more information.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

It is unsafe to consume alcohol while using Adoxi 20mg Injection Combipack since it may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Unsafe

It is unsafe to use Adoxi 20mg Injection Combipack in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using Adoxi 20mg Injection Combipack .

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Breast Feeding

Unsafe

Adoxi 20mg Injection Combipack is not recommended during breastfeeding since it may be unsafe for the breastfed infant. Please seek medical advice if you are a nursing mother before starting Adoxi 20mg Injection Combipack .

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Driving

Unsafe

Adoxi 20mg Injection Combipack causes dizziness and drowsiness that may affect your ability to drive. Do not drive or operate machinery if you experience unmanageable side effects with Adoxi 20mg Injection Combipack .

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Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment. Before being treated with Adoxi 20mg Injection Combipack , your doctor may advise you of blood tests to check your liver functioning.

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Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting Adoxi 20mg Injection Combipack .

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Children

Unsafe

Safety and efficacy of Adoxi 20mg Injection Combipack have not been established in patients younger than 18 years.

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Keep Refrigerated. Do not freeze.

About Adoxi 20mg Injection Combipack

Adoxi 20mg Injection Combipack belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

Adoxi 20mg Injection Combipack contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

Adoxi 20mg Injection Combipack will be administered by a healthcare professional. Your doctor will decide the dosage depending on your medical condition. The common side effects of Adoxi 20mg Injection Combipack include pain/swelling at the injection site, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, insomnia (sleeplessness), fever (please inform your doctor if you have fever), muscle aches, and breathlessness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use or stop this medicine if the doctor did not advise you. Before starting Adoxi 20mg Injection Combipack , let your doctor know if you have any allergic reactions, medical history of liver or kidney diseases, heart diseases, blood pressure problems, fits, lung disorders, weak immune system, anemia, low white blood cell count, vision problems, and are receiving chemotherapy. Adoxi 20mg Injection Combipack is not indicated for use in pregnant and breastfeeding women. Adoxi 20mg Injection Combipack may make you feel dizzy and drowsy, hence do not drive or operate machinery. It is not recommended to consume alcohol along with Adoxi 20mg Injection Combipack . Adoxi 20mg Injection Combipack is not recommended for children below two years of age.

Uses of Adoxi 20mg Injection Combipack

Cancer.

Medicinal Benefits Mweb

Medicinal Benefits

Adoxi 20mg Injection Combipack contains Docetaxel that belongs to the family of anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent and prevents cancer cells from rapidly dividing and spreading. Docetaxel may be used alone or in combination with other chemotherapy drugs to treat breast cancer that has spread to the tissues and lymph nodes (locally advanced breast cancer) and other parts (secondary breast cancer). It is also used in prostate cancer that does not respond to hormone treatment. It is further being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Side Effects of Adoxi 20mg Injection Combipack

  • Pain/swelling at the injection site
  • Headache
  • Fatigue
  • Dizziness
  • Drowsiness
  • Constipation
  • Loss of appetite
  • Indigestion
  • Tearing of the eyes
  • Nausea
  • Vomiting
  • Diarrhoea
  • Insomnia (sleeplessness)
  • Fever (please inform your doctor if you have fever)
  • Muscle aches
  • Breathlessness

Drug Warnings

Inform your doctor if you have any allergic reactions to Adoxi 20mg Injection Combipack or other medications. Before starting Adoxi 20mg Injection Combipack , let your doctor know if you have any medical history of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Adoxi 20mg Injection Combipack can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, Adoxi 20mg Injection Combipack is not indicated in pregnancy and breastfeeding women. If you are using Adoxi 20mg Injection Combipack , use reliable contraception forms to prevent pregnancy during the course. Adoxi 20mg Injection Combipack can make you feel dizzy and drowsy, thus affecting your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with Adoxi 20mg Injection Combipack . Adoxi 20mg Injection Combipack is not recommended for patients younger than 18 years of age.

Drug-Drug Interactions

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DocetaxelCladribine
Severe
DocetaxelCeritinib
Severe

Drug-Drug Interactions

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DocetaxelCladribine
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
The combined use of cladribine with Adoxi 20mg Injection Combipack 0.5 ml can increase the risk of serious infections.

How to manage the interaction:
Taking Adoxi 20mg Injection Combipack 0.5 ml with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
DocetaxelCeritinib
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
Taking ceritinib and may significantly increase the blood levels of Adoxi 20mg Injection Combipack 0.5 ml.

How to manage the interaction:
Taking Adoxi 20mg Injection Combipack 0.5 ml with Ceritinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like nausea, vomiting, diarrhea, mouth sores, fluid retention, nerve pain, numbness, tingling, muscle pain or weakness, paleness, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to a doctor.
DocetaxelDiltiazem
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
When Diltiazem is taken with Adoxi 20mg Injection Combipack 0.5 ml, it can slow down the breakdown of Adoxi 20mg Injection Combipack 0.5 ml in the body.

How to manage the interaction:
Taking Diltiazem with Adoxi 20mg Injection Combipack 0.5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like feeling sick, throwing up, having diarrhea, mouth sores, swelling, nerve pain, or weakness, it's important to let your doctor know. They might have other options for you that won't cause these problems. Other symptoms like feeling tired, dizzy, or having trouble breathing, losing weight, or pain when you pee should also be reported to your doctor right away. Do not stop using any medications without first talking to your doctor.
DocetaxelClarithromycin
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
When Adoxi 20mg Injection Combipack 0.5 ml is taken with Clarithromycin, it can slow down the way the body breaks down Adoxi 20mg Injection Combipack 0.5 ml.

How to manage the interaction:
Taking Clarithromycin with Adoxi 20mg Injection Combipack 0.5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - feeling sick, throwing up, having diarrhea, mouth sores, retaining fluids, nerve pain, numbness, tingling, muscle pain, weakness, anemia, bleeding problems, looking pale, feeling tired, dizzy, bleeding, bruising, having a fever, chills, a sore throat, muscle aches, trouble breathing, losing weight, feeling pain or burning when you pee, or bleeding - make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
DocetaxelCiclosporin
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
Coadministration of Adoxi 20mg Injection Combipack 0.5 ml with ciclosporin may significantly increase the blood levels of Adoxi 20mg Injection Combipack 0.5 ml.

How to manage the interaction:
Although there is a possible interaction between deferasirox and ciclosporin, they can be taken together if your doctor has prescribed them. Contact your doctor immediately if experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
DocetaxelMifepristone
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
Co-administration of Adoxi 20mg Injection Combipack 0.5 ml with mifepristone may significantly increase the levels of mifepristone, which may increase the risk of side effects.

How to manage the interaction:
Taking Adoxi 20mg Injection Combipack 0.5 ml with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm(coughing fluid), red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue any medications without consulting a doctor.
DocetaxelAmiodarone
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
Coadministration of Amiodarone with Adoxi 20mg Injection Combipack 0.5 ml may significantly increase the blood levels of Adoxi 20mg Injection Combipack 0.5 ml.

How to manage the interaction:
Co-administration of Adoxi 20mg Injection Combipack 0.5 ml with Amiodarone can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, make sure to consult a doctor. Do not stop using any medications without talking to a doctor.
DocetaxelKetoconazole
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
Coadministration of Ketoconazole and Adoxi 20mg Injection Combipack 0.5 ml may significantly increase the blood levels of Adoxi 20mg Injection Combipack 0.5 ml. This may increase risk of side effects.

How to manage the interaction:
Although taking Ketoconazole and Adoxi 20mg Injection Combipack 0.5 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in your coughing, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, you should consult a doctor immediately. do not discontinue any medication without consulting a doctor.
DocetaxelTofacitinib
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
Taking Tofacitinib with Adoxi 20mg Injection Combipack 0.5 ml may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Adoxi 20mg Injection Combipack 0.5 ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
DocetaxelVoriconazole
Severe
How does the drug interact with Adoxi 20mg Injection Combipack 0.5 ml:
Taking Adoxi 20mg Injection Combipack 0.5 ml with Voriconazole may significantly increase the blood levels of Adoxi 20mg Injection Combipack 0.5 ml.

How to manage the interaction:
Although taking Adoxi 20mg Injection Combipack 0.5 ml and Voriconazole together may result in an interaction, they can be taken together if a doctor prescribes it. However, if you experience dizziness, fever, chills, diarrhea, sore throat, muscle pain, shortness of breath, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ITRACONAZOLE
  • ERYTHROMYCIN
  • RIFABUTIN
  • METRONIDAZOLE
  • TINIDAZOLE
  • RITONAVIR
  • DISULFIRAM
  • CODEINE
  • HYDROCODONE
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE

Habit Forming

No

Special Advise

  • Your doctor may advise regular physical exams and mammograms to rule out the possibility of breast cancer.
  • Self-examine your breasts to check for any lumps monthly.
  • Your doctor may also advise liver function tests to monitor your liver health.
  • Your doctor may advise blood tests and regular examinations of the prostate.

Diet & Lifestyle Advise

  • Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Include whole grains, legumes, and follow a plant-based diet. Limiting dietary fats is advised during the breast cancer phase. Instead, include healthy fats, such as olive oil, avocado, nuts, seeds, and fatty fish
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk, and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Adoxi 20mg Injection Combipack Substitute

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