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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

VINORELBINE-10MG

Manufacturer/Marketer :

Adley Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

2/236, KAMBRATH THAZAM, PULLALUR, KURUVATTOOR PO, NA KOZHIKODE Kozhikode Kerala 673012
Other Info - ADV0109

FAQs

Advin Injection 5 ml works by stopping or slowing the growth of cancer cells in the body.

Use effective contraception and avoid fathering a child during treatment with Advin Injection 5 ml and four months after the end of the treatment. Discuss with the doctor about sperm conservation prior to treatment with Advin Injection 5 ml, as it may alter your fertility.

Advin Injection 5 ml may cause a severe decrease in white blood cells in the bone marrow. This might increase the risk of developing serious infections. Your doctor may advise regular tests to check the number of white blood cells in your body. Consult the doctor immediately if you experience fever, cough, congestion, sore throat or other signs of infection.

Advin Injection 5 ml may cause constipation. Consult your doctor if you experience constipation; the doctor may advise about changing your diet or using medicines to prevent/treat constipation.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is not known if alcohol affects Advin Injection 5 ml. Please consult your doctor.

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Pregnancy

Unsafe

Do not use Advin Injection 5 ml if you are pregnant or think you may be pregnant. Consult the doctor immediately if you become pregnant during treatment with Advin Injection 5 ml.

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Breast Feeding

Unsafe

Do not take Advin Injection 5 ml if you are breastfeeding. Breastfeeding must be discontinued if treatment with Advin Injection 5 ml is necessary.

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Driving

Caution

In a few people, Advin Injection 5 ml may cause dizziness or lightheadedness. Do not drive or operate heavy machinery if you experience these symptoms.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Advin Injection 5 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a history of kidney diseases, inform your doctor before receiving Advin Injection 5 ml.

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Children

Unsafe

Advin Injection 5 ml is not recommended for children below 18 years as safety and effectiveness have not been established.

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Keep Refrigerated. Do not freeze.

About Advin Injection 5 ml

Advin Injection 5 ml belongs to the group of medicines called vinca alkaloids used alone or in combination with other anti-cancer medicines to treat non-small cell lung cancer that has spread to other body parts and advanced breast cancer that has not responded to other medicines. 
 
Advin Injection 5 ml contains Vinorelbine, which works by stopping or slowing the growth of cancer cells in the body.
 
In some cases, Advin Injection 5 ml may cause side effects such as nausea, vomiting, constipation, injection site reactions, and a decrease in white and red blood cells. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Advin Injection 5 ml if you are pregnant, breastfeeding, or think you may be pregnant. Advin Injection 5 ml is not recommended for children below 18 years. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Advin Injection 5 ml

Non-small cell lung cancer, breast cancer.

Medicinal Benefits Mweb

Medicinal Benefits

Advin Injection 5 ml belongs to the group of medicines called vinca alkaloids used to treat locally advanced or metastatic non-small cell lung cancer and advanced breast cancer that has not responded to other medicines. It may also be used to treat cancer of the oesophagus and soft tissue sarcoma (cancer that forms in the muscles). Advin Injection 5 ml contains Vinorelbine, which works by stopping the growth and multiplication of cancer cells. 

Directions for Use

Advin Injection 5 ml will be administered by a doctor with experience in the use of chemotherapy medications.

Side Effects of Advin Injection 5 ml

  • Nausea
  • Vomiting
  • Constipation
  • Injection site reactions like redness, burning pain, inflammation of veins, or vein discolouration
  • A decrease in red or white blood cells
  • Weakness of lower extremities
  • Liver disorders (abnormal liver tests)

Drug Warnings

Do not use Advin Injection 5 ml if you are allergic to any of its components, if you are pregnant, think you might be pregnant or breastfeeding, if you have low white blood cell count, have/had a severe infection within two weeks, have thrombocytopenia (low platelet count), or if you have taken or plan to receive yellow fever vaccination. Inform the doctor if you have a history of heart attack, severe chest pain, liver problems, and signs or symptoms of infection. Consult the doctor immediately if you become pregnant during treatment with Advin Injection 5 ml. Seek immediate medical attention if you experience symptoms of pulmonary embolism (chest pain, breathlessness, and fainting), posterior reversible encephalopathy syndrome (headaches, changed mental state which may lead to confusion and coma, convulsions, blurred vision and high blood pressure), infection (cough, fever, and chills), severe constipation with abdominal pain, acute respiratory distress syndrome (difficulty breathing), severe reduced blood pressure (severe dizziness and lightheadedness when you stand up), severe chest pain, or allergic reactions (dizziness, rash, swelling of the eyelids, face, lips or throat).

Drug-Drug Interactions

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VinorelbineEtanercept
Severe
VinorelbineInfliximab
Severe

Drug-Drug Interactions

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VinorelbineEtanercept
Severe
How does the drug interact with Advin Injection 5 ml:
When Etanercept is used with Advin Injection 5 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Advin Injection 5 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
VinorelbineInfliximab
Severe
How does the drug interact with Advin Injection 5 ml:
When Advin Injection 5 ml and Infliximab are taken together, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Advin Injection 5 ml together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VinorelbinePosaconazole
Severe
How does the drug interact with Advin Injection 5 ml:
Combining posaconazole and Advin Injection 5 ml can raise the levels of Advin Injection 5 ml in the blood and increase its effects.

How to manage the interaction:
Although using Posaconazole and Advin Injection 5 ml together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience constipation, abdominal pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, seizures, unusual or excessive bleeding, easy bruising, paleness, fatigue, fainting, fever, chills, sore throat, or other flu-like symptoms. Do not stop taking any medications without consulting a doctor.
VinorelbineClarithromycin
Severe
How does the drug interact with Advin Injection 5 ml:
When Advin Injection 5 ml is taken with Clarithromycin, it can cause a decrease in the metabolism of Advin Injection 5 ml.

How to manage the interaction:
Although taking Clarithromycin and Advin Injection 5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like constipation, stomach pain, or difficulty peeing, it's important to let your doctor know. They can recommend other options that won't cause these problems. You should also contact your doctor right away if you notice any numbness, weakness, trouble walking, or hearing loss. Other symptoms like seizures, bleeding, fatigue, or fever should also be reported to your doctor. Do not stop using any medications without a doctor's advice.
VinorelbineCladribine
Severe
How does the drug interact with Advin Injection 5 ml:
Combining Cladribine with Advin Injection 5 ml can increase the risk and severity of developing serious infections.

How to manage the interaction:
Taking Cladribine with Advin Injection 5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PHENYTOIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • MITOMYCIN
  • TACROLIMUS
  • CICLOSPORIN

Habit Forming

No

Special Advise

  • Your doctor may advise regular blood tests before and during treatment with Advin Injection 5 ml to check if it is safe for you to receive the treatment.
  • Inform the doctor if you are due to take any vaccinations, as many vaccines (live attenuated vaccines) are not recommended during treatment with Advin Injection 5 ml.
  • Women of childbearing potential must use effective contraception during treatment and for seven months after the end of the treatment.
  • If you are a man being treated with Advin Injection 5 ml, discuss with the doctor about sperm conservation. Men are advised to use effective contraception during treatment and for four months after the end of the treatment. 

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods like spinach, lettuce, squashes, broccoli, nuts, seeds, beans, whole wheat pasta, whole wheat bread, brown rice and fruits.

Advin Injection 5 ml Substitute

Substitutes safety advice
  • Cevin 10mg Injection

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    2317.50per tablet
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    3945.00per tablet
  • Vinotec 10 mg Injection 1's

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    3448.10per tablet
  • Vinbicel Injection 1's

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    2697.80per tablet
  • Vinotec 50 Injection 5 ml

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    2667.46per tablet
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