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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

Not for online sale
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in last 90 days

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- TUBERCULOSIS

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - AKT0006

FAQs

Akt-2 Tablet works by killing Mycobacterium tuberculosis which causes TB (tuberculosis).

Akt-2 Tablet may cause reddish-orange discolouration of body fluids such as tears, sputum and urine; this is not harmful and does not require medical attention. However, consult your doctor if you have any concerns.

Akt-2 Tablet might stain soft contact lenses. The child should use spectacles and avoid wearing contact lens while taking Akt-2 Tablet .

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Consult your doctor

Please consult the doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Consult your doctor

Please consult the doctor if your child has kidney problems.

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Children

Safe if prescribed

Akt-2 Tablet is safe for children if prescribed by the doctor. Your doctor may prescribe the dose and duration based on the child's condition and age.

About Akt-2 Tablet

Akt-2 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.
 
Akt-2 Tablet contains Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, Akt-2 Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).
 
In some cases, Akt-2 Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.
 
Let your doctor know if your child is allergic to any of the components in Akt-2 Tablet . Keep your doctor informed about your child's health condition and medications to rule out any side effects/interactions.

Uses of Akt-2 Tablet

Tuberculosis.

Medicinal Benefits Mweb

Medicinal Benefits

Akt-2 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. Akt-2 Tablet contains two anti-mycobacterial agents, Rifampicin and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, Akt-2 Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Directions for Use

Akt-2 Tablet should be given on an empty stomach, i.e., one hour prior or two hours after meals.Liquid: Administer the prescribed dose using a measuring cup/dosing syringe/dropper. Shake the bottle well before use.

Side Effects of Akt-2 Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Loss of appetite

Drug Warnings

Do not give Akt-2 Tablet to the child if he/she is allergic to any of the components in Akt-2 Tablet , if he/she has acute liver disease, drug-induced liver disease, if the child has experienced liver damage linked to rifampicin or isoniazid, or if the child is taking anti-fungal (voriconazole) or medicines for HIV infection (protease inhibitors). Akt-2 Tablet may cause liver damage; consult your doctor if the child experiences symptoms such as unexplained loss of appetite, nausea, vomiting, jaundice, dark urine, persistent fatigue for more than 3 days, abdominal pain and tenderness. Consult a doctor if your child gets flu-like symptoms such as headache, fever, or muscle ache. Inform the doctor if your child has HIV infection, epilepsy, psychiatric disorder, diabetes, porphyria, phenylketonuria (metabolic disorder), peripheral neuropathy (tingling sensation in hands and feet), kidney or liver problems, if your child is allergic to ethionamide or niacin (nicotinic acid), or if your child is taking cortisone or any cortisone-like drug. 

Drug-Drug Interactions

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RifampicinIndinavir
Critical
RifampicinVoriconazole
Critical

Drug-Drug Interactions

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RifampicinIndinavir
Critical
How does the drug interact with Akt-2 Tablet:
When Indinavir is taken with Akt-2 Tablet, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Akt-2 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinVoriconazole
Critical
How does the drug interact with Akt-2 Tablet:
Taking Voriconazole with Akt-2 Tablet can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with Akt-2 Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinSaquinavir
Critical
How does the drug interact with Akt-2 Tablet:
Taking saquinavir with Akt-2 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Akt-2 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinPirfenidone
Critical
How does the drug interact with Akt-2 Tablet:
Taking pirfenidone with Akt-2 Tablet can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and Akt-2 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinDarunavir
Critical
How does the drug interact with Akt-2 Tablet:
Taking darunavir with Akt-2 Tablet can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Akt-2 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinRanolazine
Critical
How does the drug interact with Akt-2 Tablet:
When ranolazine is taken with Akt-2 Tablet, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Akt-2 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsoniazidLovastatin
Critical
How does the drug interact with Akt-2 Tablet:
When Lovastatin is taken with Akt-2 Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Akt-2 Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with Akt-2 Tablet:
When Lomitapide is taken with Akt-2 Tablet, Akt-2 Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Akt-2 Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidRegorafenib
Critical
How does the drug interact with Akt-2 Tablet:
When Akt-2 Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Akt-2 Tablet is not recommended, it taken can be taken if prescribed by the doctor.
RifampicinLeflunomide
Severe
How does the drug interact with Akt-2 Tablet:
Taking leflunomide with Akt-2 Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Akt-2 Tablet together with Leflunomide can result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience joint pain or swelling, unusual bleeding, fatigue, abdominal pain, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • VORICONAZOLE
  • SAQUINAVIR
  • RITONAVIR
  • DISULFIRAM

Habit Forming

No

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help in improving the immune system. 
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from cough.

Akt-2 Tablet Substitute

Substitutes safety advice
  • Macox Plus Tablet 6's

    by Others

    12.90per tablet
  • MYCOCOX TABLET

    by Others

    6.84per tablet
  • RINIZIDE FORTE DT TABLET

    by Others

    5.63per tablet
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