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  3. AKURIT Z KID TABLET

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
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AKURIT Z KID TABLET, Pack of 6 TABLETS
Not for online sale
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Whats That

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Composition :

ISONIAZID-60MG + PYRAZINAMIDE-30MG + RIFAMPICIN-150MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- TUBERCULOSIS

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - AKU0004

Author Details

Doctor imageDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Doctor image

Reviewed By

Sunny S

MBBS

Last Updated

Aug 20, 2024 | 12:55 PM IST

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FAQs

AKURIT Z KID TABLET is a combination of three anti-tuberculosis drugs, namely: Rifampicin, Isoniazid, and Pyrazinamide. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Pyrazinamide inhibits the growth of the bacteria. Together, AKURIT Z KID TABLET kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Do not stop taking AKURIT Z KID TABLET despite symptomatic relief. To treat your condition effectually, continue taking AKURIT Z KID TABLET for as long as it has been prescribed for you.

Do not take AKURIT Z KID TABLET along with antacids as it might decrease the effectiveness of AKURIT Z KID TABLET. Maintain a minimum gap of 1 hour between both.

Consult your doctor before taking AKURIT Z KID TABLET with other medicines. Medicines used to treat TB, such as PAS (P-amino salicylic acid) and cycloserine, should be taken 8 hours apart from AKURIT Z KID TABLET if prescribed.

AKURIT Z KID TABLET contains isoniazid which might interact with foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer. Avoid these foods while taking AKURIT Z KID TABLET.

AKURIT Z KID TABLET might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking AKURIT Z KID TABLET. Consult your doctor if you have any concerns regarding this; your doctor may suggest an alternate method of contraception.

AKURIT Z KID TABLET may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time, even after you stop taking AKURIT Z KID TABLET. Do not worry as it is a common side-effect of AKURIT Z KID TABLET.

Yes, AKURIT Z KID TABLET might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking AKURIT Z KID TABLET.

AKURIT Z KID TABLET may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking AKURIT Z KID TABLET.

AKURIT Z KID TABLET may cause liver problems, especially in people aged 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking AKURIT Z KID TABLET to check how your liver is functioning.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid alcohol consumption while taking AKURIT Z KID TABLET as it could lead to increased liver damage.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, planning for pregnancy or think you are pregnant; your doctor will prescribe AKURIT Z KID TABLET only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

AKURIT Z KID TABLET passes into breast milk. Do not breastfeed while taking AKURIT Z KID TABLET.

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Driving

Unsafe

AKURIT Z KID TABLET may cause dizziness, vision problems, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking AKURIT Z KID TABLET if you have liver impairment/liver disease before taking AKURIT Z KID TABLET.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking AKURIT Z KID TABLET.

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Children

Consult your doctor

Please consult your doctor. Your doctor may suggest suitable dose and dosage form based on your child's age, body weight and medical condition. Kid tablets could be used in children if prescribed by the doctor.

Reference

  1. https://www.medicines.org.uk/emc/files/pil.1596.pdf
  2. https://www.drugs.com/mtm/isoniazid-pyrazinamide-and-rifampin.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050705s013lbl.pdf

About AKURIT Z KID TABLET

AKURIT Z KID TABLET belongs to the group of medicines called 'anti-tuberculosis drugs' primarily used to treat tuberculosis. Also known as TB, Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine, and bone marrow. AKURIT Z KID TABLET does not work against infections caused by the virus, including cold and flu.

AKURIT Z KID TABLET is a combination of three anti-tuberculosis drugs, namely: Rifampicin, Isoniazid and Pyrazinamide. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Pyrazinamide inhibits the growth of the bacteria. Together, AKURIT Z KID TABLET kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Take AKURIT Z KID TABLET as prescribed. In some cases, you may experience certain common side-effects such as weakness, nausea, vomiting, stomach pain, and joint or muscle pain. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while taking AKURIT Z KID TABLET as they might cause interaction. Maintain a gap of one hour between AKURIT Z KID TABLET and antacid medicines. Consult your doctor before taking AKURIT Z KID TABLET if you are pregnant. Avoid breastfeeding while taking AKURIT Z KID TABLET as it passes into breast milk. 

Uses of AKURIT Z KID TABLET

Tuberculosis

Medicinal Benefits Mweb

Medicinal Benefits

AKURIT Z KID TABLET is a combination of three anti-tuberculosis drugs, namely: Rifampicin, Isoniazid, and Pyrazinamide. AKURIT Z KID TABLET belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Rifampicin inhibits DNA dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Pyrazinamide inhibits the growth of the bacteria. Together, AKURIT Z KID TABLET kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Directions for Use

Tablet/Capsule: Take it on an empty stomach, i.e., 30 minutes before food or 2 hours after food. Swallow it as a whole; do not crush or chew it.Dispersible tablet: Disperse the tablet in a teaspoonful of boiled and cooled water before administration.

Side Effects of AKURIT Z KID TABLET

  • Weakness
  • Nausea
  • Vomiting
  • Stomach pain
  • Joint or muscle pain

Drug Warnings

Do not take AKURIT Z KID TABLET if you are allergic to any of its contents; if you have jaundice, or if you are taking HIV medicines (saquinavir or ritonavir). Before starting AKURIT Z KID TABLET, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while taking AKURIT Z KID TABLET as they might cause interaction. Maintain a gap of one hour between AKURIT Z KID TABLET and antacid medicines. Consult your doctor before taking AKURIT Z KID TABLET if you are pregnant. Avoid breastfeeding while taking AKURIT Z KID TABLET as it passes into breast milk. AKURIT Z KID TABLET may cause dizziness, and vision problems, so drive with caution. Avoid alcohol consumption while taking AKURIT Z KID TABLET as it could lead to increased liver damage. Keep your doctor informed about your health condition and all the medicines you are taking to rule out any interactions.

Drug-Drug Interactions

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RifampicinIndinavir
Critical
RifampicinVoriconazole
Critical

Drug-Drug Interactions

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RifampicinIndinavir
Critical
How does the drug interact with Akurit Z Kid Tablet:
When Indinavir is taken with Akurit Z Kid Tablet, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Akurit Z Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinVoriconazole
Critical
How does the drug interact with Akurit Z Kid Tablet:
Taking Voriconazole with Akurit Z Kid Tablet can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with Akurit Z Kid Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinSaquinavir
Critical
How does the drug interact with Akurit Z Kid Tablet:
Taking saquinavir with Akurit Z Kid Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Akurit Z Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinPirfenidone
Critical
How does the drug interact with Akurit Z Kid Tablet:
Taking pirfenidone with Akurit Z Kid Tablet can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and Akurit Z Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinDarunavir
Critical
How does the drug interact with Akurit Z Kid Tablet:
Taking darunavir with Akurit Z Kid Tablet can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Akurit Z Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinRanolazine
Critical
How does the drug interact with Akurit Z Kid Tablet:
When ranolazine is taken with Akurit Z Kid Tablet, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Akurit Z Kid Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsoniazidLovastatin
Critical
How does the drug interact with Akurit Z Kid Tablet:
When Lovastatin is taken with Akurit Z Kid Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Akurit Z Kid Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with Akurit Z Kid Tablet:
When Lomitapide is taken with Akurit Z Kid Tablet, Akurit Z Kid Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Akurit Z Kid Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidRegorafenib
Critical
How does the drug interact with Akurit Z Kid Tablet:
When Akurit Z Kid Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Akurit Z Kid Tablet is not recommended, it taken can be taken if prescribed by the doctor.
RifampicinLeflunomide
Severe
How does the drug interact with Akurit Z Kid Tablet:
Taking leflunomide with Akurit Z Kid Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Akurit Z Kid Tablet together with Leflunomide can result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience joint pain or swelling, unusual bleeding, fatigue, abdominal pain, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • ACETAMINOPHEN
  • INSULIN ISOPHANE
  • SAQUINAVIR
  • RITONAVIR
  • ERGOCALCIFEROL

Habit Forming

No

Special Advise

  • AKURIT Z KID TABLET may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking AKURIT Z KID TABLET.
  • Your doctor may advise you to get regular liver tests while taking AKURIT Z KID TABLET to check how your liver is functioning.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, helps in improving the immune system. 
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help relieve cough.
  • Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.
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