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Alzumab 25mg Injection contains Itolizumab, an immunomodulator. It reduces the synthesis of pro-inflammatory markers called cytokines. Thus, it helps in decreasing inflammation in various diseases like psoriasis, rheumatoid arthritis, and multiple sclerosis.
When a person is infected with the coronavirus, his/her immune system responds in such a way that it sends useful immune chemicals to the affected areas of the lungs to fight the infection. However, in some people, this release of immune chemicals is overactive, resulting in a cytokine storm, an excessive immune response in the lungs. This can further lead to severe breathing complications in an infected person. Alzumab 25mg Injection reduces this cytokine storm and further prevents the inflammation and damage in the lungs of a COVID-19 infected person.
Alzumab 25mg Injection is currently being used to decrease the negative outcome of the cytokine storm in critically, severely and moderately ill COVID-19 patients.
Alzumab 25mg Injection is not recommended for every person infected with the coronavirus. Alzumab 25mg Injection is only prescribed by doctors in patients with severe and critical COVID infection.
Alzumab 25mg Injection is to be carefully administered with caution in patients under doctor's supervision only. The safety of Alzumab 25mg Injection is not yet evaluated in conditions like neutropenia (low levels of neutrophils), lymphopenia (low levels of lymphocytes), AIDS, tuberculosis, hepatitis B and C.
Even if there is no improvement after administering Alzumab 25mg Injection, your doctor may suggest an alternate course. Please note that Alzumab 25mg Injection does not reverse the damage caused due to coronavirus infection, but it will further prevent the inflammation of the lungs. It is also advised to medically examine for other lung and heart related dysfunctions even the patient suffers breathlessness after Alzumab 25mg Injection administration.
It is not recommended to get live attenuated vaccines while being treated with Alzumab 25mg Injection. This may lead to serious conditions. Please consult a doctor before you start Alzumab 25mg Injection if you are undergoing any vaccinations.
Alcohol
Caution
You are recommended to avoid alcohol consumption while taking Alzumab 25mg Injection. Alcohol intake, along with Alzumab 25mg Injection, may cause increased dizziness.
Pregnancy
Unsafe
Alzumab 25mg Injection is not recommended during pregnancy since it may have harmful effects on the developing baby. Your doctor will prescribe Alzumab 25mg Injection only if the benefit outweighs the risk.
Breast Feeding
Caution
It is not known if Alzumab 25mg Injection passes into the breastmilk when used by breastfeeding mother. Your doctor will prescribe Alzumab 25mg Injection only if the benefit outweighs the risk.
Driving
Unsafe
Alzumab 25mg Injection may make you feel dizzy. Do not drive or operate machinery if you experience dizziness.
Liver
Caution
Please consult your doctor since Alzumab 25mg Injection should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed in patients with liver impairment. However, Alzumab 25mg Injection is not recommended in patients with active liver diseases.
Kidney
Caution
Please consult your doctor since Alzumab 25mg Injection should be used with caution in patients with kidney impairment/kidney disease. Dose adjustment may be required.
Children
Unsafe
Alzumab 25mg Injection is not recommended in children and adolescents younger than 18 years of age.
About Alzumab 25mg Injection
Alzumab 25mg Injection belongs to the class of 'immunomodulators', primarily used to treat psoriasis. Psoriasis is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. Alzumab 25mg Injection may also be used to treat autoimmune conditions like rheumatoid arthritis and multiple sclerosis. Alzumab 25mg Injection is currently being used and trialled to treat cytokine storm (excessive immune response) in COVID-19 (Corona Virus Disease-19) patients.
Alzumab 25mg Injection consists of 'Itolizumab' that is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody (that serve as a substitute antibody). It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, Alzumab 25mg Injection is also being used in COVID-19 infection to reduce the severity of inflammation and damage in the lungs. It is thought to decrease the cytokine storm, an excessive immune response in the lungs of a COVID-19 infected person.
Your doctor will decide the dose and duration based on the medical condition. Common side effects of Alzumab 25mg Injection include pain and swelling at the injection site, upper respiratory tract infection, fever, itching, dizziness, and diarrhoea. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.
Before starting Alzumab 25mg Injection, inform your doctor if you have any liver, heart or kidney diseases, bone marrow suppression, weak immune system (HIV), tuberculosis, hepatitis B, and active infections. Let your doctor know if you are pregnant or breastfeeding before starting Alzumab 25mg Injection. Alzumab 25mg Injection may cause dizziness, so drive only if you are alert and focused. Alzumab 25mg Injection should not be given to children and adolescents under 18 years of age as safety has not been established. Avoid consuming alcohol along with Alzumab 25mg Injection as it could lead to increased dizziness.
Uses of Alzumab 25mg Injection
Medicinal Benefits
Alzumab 25mg Injection treats inflammation in patients with psoriasis and rheumatoid arthritis. It contains 'Itolizumab,' which is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody. It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, Alzumab 25mg Injection is also being used in COVID-19 infection to reduce breathing complications, the severity of inflammation, and damage in the lungs. It is being used to decrease the cytokine storm, an excessive immune response that occurs in the lungs of a COVID-19-infected person.
Directions for Use
Side Effects of Alzumab 25mg Injection
Drug Warnings
Inform your doctor if you have any liver, heart or kidney diseases, bone marrow suppression, low blood cell count, weak immune system (HIV), neutropenia (low levels of neutrophils), lymphopenia (low levels of lymphocytes), tuberculosis, hepatitis B, C, and active infections before starting Alzumab 25mg Injection. Avoid close contact with people who have infections like chickenpox, measles, tuberculosis, and flu that can be easily spread. Thoroughly wash your hands to prevent the spread of infection. Do not take live vaccines while being treated with Alzumab 25mg Injection to prevent any serious consequences. Alzumab 25mg Injection may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with Alzumab 25mg Injection as it could lead to increased dizziness. Alzumab 25mg Injection is not recommended in children and adolescents younger than 18 years of age as safety and efficacy is not established. Store Alzumab 25mg Injection at temperatures of 2°C to 8°C. Do not freeze the vial.
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