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Written By ,
Reviewed By Sunny S , MBBS

Composition :

AMANTADINE-129MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - AMA0130

FAQs

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About Amantrel ER 129 Tablet

Uses of Amantrel ER 129 Tablet

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Amantrel ER 129 Tablet

Drug Warnings

Drug-Drug Interactions

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AmantadineIopamidol
Severe

Drug-Drug Interactions

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How does the drug interact with Amantrel ER 129 Tablet:
Coadministration of Allopurinol with Trihexyphenidyl may increase side effects such as heat intolerance, dry mouth, confusion, constipation, difficulty urinating, and blurred vision especially in the elderly or those with a debilitating (physically weak) condition.

How to manage the interaction:
If you are supposed to take Allopurinol and Trihexyphenidyl together, your doctor may adjust the dose or monitor you more frequently to safely use both medications.
AmantadineIopamidol
Severe
How does the drug interact with Amantrel ER 129 Tablet:
Coadministration of Amantrel ER 129 Tablet with Iopamidol may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
There may be a possibility of interaction between Amantrel ER 129 Tablet and Iopamidol, but it can be taken if prescribed by a doctor. If you have seizures or a head injury, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
AmantadineMetrizamide
Severe
How does the drug interact with Amantrel ER 129 Tablet:
Coadministration of Amantrel ER 129 Tablet with Metrizamide may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Coadministration of Amantrel ER 129 Tablet with Metrizamide can cause an interaction, but it can be taken if prescribed by a doctor. However, if you experience Nausea, dizziness (lightheadedness), or insomnia (a condition that makes it hard to fall or stay asleep) call a doctor. Do not discontinue any medications without consulting a doctor.
AmantadineEsketamine
Severe
How does the drug interact with Amantrel ER 129 Tablet:
Taking Amantrel ER 129 Tablet with Esketamine can lead to or increase the risk or severity of developing side effects.

How to manage the interaction:
Taking Amantrel ER 129 Tablet with Esketamine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, drowsiness, fainting, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amantrel ER 129 Tablet:
Coadministration of Amantrel ER 129 Tablet with Bupropion may increase the risk of seizures (fits).

How to manage the interaction:
Taking Amantrel ER 129 Tablet with Bupropion together can result in an interaction, it can be taken if a doctor has advised it. However, if you have symptoms of seizures, hallucinations, muscle stiffness, fainting, fast or uneven heartbeat, shallow breathing, and chest pain or tightness, contact a doctor. Do not stop using any medications without talking to a doctor.
AmantadineAclidinium bromide
Severe
How does the drug interact with Amantrel ER 129 Tablet:
Coadministration of Amantrel ER 129 Tablet with Aclidinium bromide may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Amantrel ER 129 Tablet and Aclidinium bromide, you can take these medicines together if prescribed by your doctor. However, if your side effects worsen, please consult your doctor.
How does the drug interact with Amantrel ER 129 Tablet:
The combined use of Amantrel ER 129 Tablet with tramadol can increase the risk or severity of seizures (fits), The risk increases in elderly, patients undergoing alcohol or drug withdrawal, who have a history of seizures, brain tumors, or head trauma.

How to manage the interaction:
Taking Amantrel ER 129 Tablet and tramadol together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as seizures, dizziness, drowsiness, or difficulty concentrating, contact a doctor immediately. Do not discontinue the medication without a doctor's advice. Avoid activities requiring mental alertness such as driving or operating hazardous machinery while taking these medications.
AmantadineIohexol
Severe
How does the drug interact with Amantrel ER 129 Tablet:
Coadministration of Amantrel ER 129 Tablet with Iohexol may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although taking Amantrel ER 129 Tablet and Iohexol together can cause an interaction, it can be taken if your doctor has suggested it. If you have seizures or a head injury, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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AMANTADINE-129MGDepressive episode
Severe
AMANTADINE-129MGOther disorders of kidney and ureter, not elsewhere classified
Severe

Drug-Diseases Interactions

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AMANTADINE-129MGDepressive episode
Severe
How does the disease interact with Amantrel ER 129 Tablet:
Amantrel ER 129 Tablet should be administered cautiously in patients with a history of psychiatric disorders, emotional instability, or substance abuse, and particularly if they are elderly.

How to manage the interaction:
Amantrel ER 129 Tablet should be used with caution in patients with a history of psychiatric disorders, emotional instability, or substance abuse, and particularly if they are elderly.
AMANTADINE-129MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Amantrel ER 129 Tablet:
Amantrel ER 129 Tablet should be administered cautiously in patients with renal impairment.

How to manage the interaction:
Amantrel ER 129 Tablet should be used with caution in patients with kidney impairment. Dosage adjustments are recommended for patients with moderate to severe kidney failure.
AMANTADINE-129MGEpilepsy
Severe
How does the disease interact with Amantrel ER 129 Tablet:
Amantrel ER 129 Tablet may rarely precipitate or exacerbate seizure activity. Patients with epilepsy or predisposed to seizures should be monitored closely for increased seizure activity during therapy with Amantrel ER 129 Tablet.

How to manage the interaction:
Patients with epilepsy or at risk of developing seizures should be monitored closely for increased seizure activity during therapy with Amantrel ER 129 Tablet.
AMANTADINE-129MGHypotension
Severe
How does the disease interact with Amantrel ER 129 Tablet:
dopamine agonists should be monitored carefully in patients with Parkinson's disease since they may have an impaired ability to respond to an orthostatic challenge, and also in patients receiving antihypertensive drugs.

How to manage the interaction:
Amantrel ER 129 Tablet should be used carefully in patients with Parkinson's disease since they may have an impaired ability to respond to an orthostatic challenge, and also in patients receiving antihypertensive drugs (medicines used to treat high blood pressure).
AMANTADINE-129MGUnspecified nonorganic psychosis
Severe
How does the disease interact with Amantrel ER 129 Tablet:
Ordinarily, patients with major psychotic disorder should not be treated with dopaminergic antiparkinson agents, because of the risk of exacerbating psychosis.

How to manage the interaction:
Usually, patients with major psychotic disorder should not be treated with dopaminergic antiparkinson agents, because of the risk of worsening psychosis.
AMANTADINE-129MGOedema, not elsewhere classified
Moderate
How does the disease interact with Amantrel ER 129 Tablet:
Amantrel ER 129 Tablet may occasionally cause peripheral edema and, rarely, congestive heart failure. Patients with edema or congestive heart failure should be monitored closely for exacerbation of their condition. Dosage adjustments may be necessary.

How to manage the interaction:
Amantrel ER 129 Tablet may occasionally cause peripheral oedema (swelling in lower legs or hands) and, rarely, congestive heart failure. Patients with oedema or congestive heart failure should be monitored closely for worsening of their condition. Dosage adjustments may be necessary.
AMANTADINE-129MGHypotension
Moderate
How does the disease interact with Amantrel ER 129 Tablet:
Amantrel ER 129 Tablet may occasionally cause orthostatic hypotension. Patients with hypotension should be monitored for exacerbation of their condition during therapy with Amantrel ER 129 Tablet. Dosage adjustments may be necessary, and patients should be advised not to rise abruptly from a sitting or recumbent position.

How to manage the interaction:
Amantrel ER 129 Tablet may occasionally cause orthostatic hypotension (low blood pressure when standing up from sitting or lying down). Hence, patients using this medicine are advised not to rise suddenly from a sitting or lying position.

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