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Not for online sale
48 Hrs returnable
COD available

Online payment accepted

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Manufacturer/Marketer :

Innovative Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

PSYCHOTHERAPEUTICS

Country of origin

India

Manufacturer/Marketer address

501, Pearl Arcade, J.P.Road, Andheri (West), Mumbai-58, Maharashtra, INDIA
Other Info - AMI0538

Author Details

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FAQs

Amicalm-10 Tablet contains Amitriptyline and Chlordiazepoxide. Amitriptyline works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.

Amicalm-10 Tablet may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.

Do not discontinue Amicalm-10 Tablet without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking Amicalm-10 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Amicalm-10 Tablet .

Dry mouth could be a side-effect of Amicalm-10 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Constipation might occur as a side-effect of Amicalm-10 Tablet . Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you experience severe constipation.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Amicalm-10 Tablet as it may cause increased sleepiness and dizziness.

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Pregnancy

Unsafe

Avoid taking Amicalm-10 Tablet if you are pregnant unless prescribed by a doctor as it may cause birth defects.

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Breast Feeding

Caution

Consult your doctor before taking Amicalm-10 Tablet ; your doctor will decide whether Amicalm-10 Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Amicalm-10 Tablet may cause sleepiness, dizziness and might impair thinking and motor skills. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Amicalm-10 Tablet should not be given to children as safety and effectiveness have not been established.

About Amicalm-10 Tablet

Amicalm-10 Tablet is a combination medicine used to treat moderate to severe depression associated with moderate to severe anxiety. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss. Anxiety is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety and depression can occur at the same time.

Amicalm-10 Tablet is a combination of two drugs: Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). Amitriptyline works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. 

You are advised to take Amicalm-10 Tablet only for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Do not take Amicalm-10 Tablet if you are pregnant as it may cause birth defects. Consult your doctor before taking Amicalm-10 Tablet if you are breastfeeding. Avoid driving or operating machinery as Amicalm-10 Tablet causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with Amicalm-10 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Amicalm-10 Tablet

Depression associated with anxiety

Medicinal Benefits Mweb

Medicinal Benefits

Amicalm-10 Tablet is a combination of two drugs: Amitriptyline and Chlordiazepoxide. Amicalm-10 Tablet is used to treat moderate to severe depression and anxiety. Amitriptyline is a tricyclic anti-depressant that affects certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood treats depression. Chlordiazepoxide is a benzodiazepine anxiolytic that works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. Amicalm-10 Tablet has a calming effect on various functions of the brain. Thereby, Amicalm-10 Tablet helps in treating anxiety and depression. 

Directions for Use

Take Amicalm-10 Tablet with or without food. Swallow Amicalm-10 Tablet as a whole with a glass of water; do not chew or crush it.

Side Effects of Amicalm-10 Tablet

  • Drowsiness
  • Dry mouth
  • Nasal congestion
  • Constipation
  • Blurred vision
  • Dizziness
  • Bloating

Drug Warnings

Do not take Amicalm-10 Tablet if you are allergic to any of its contents, if you recently had a heart attack or heart problems, are taking monoamine oxidase inhibitors (MAOI). Do not take opioids with Amicalm-10 Tablet as it may result in increased sedation, depression, coma and death. Amicalm-10 Tablet should not be taken for longer durations as it may cause physical dependence. Inform your doctor before taking Amicalm-10 Tablet if you have bipolar disorder, eye problems, urination problems, seizures, thyroid problems, kidney or liver problems or if you are due to have any surgery. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Talk to your doctor before taking Amicalm-10 Tablet if you have a history of drug abuse, addiction or alcohol abuse as Amicalm-10 Tablet may cause dependence. Do not take Amicalm-10 Tablet if you are pregnant, as it may cause birth defects. Consult your doctor before taking Amicalm-10 Tablet if you are breastfeeding. Avoid driving or operating machinery as Amicalm-10 Tablet causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with Amicalm-10 Tablet as it could lead to increased drowsiness and dizziness. Amicalm-10 Tablet should not be given to children as safety and effectiveness have not been established.

Drug-Drug Interactions

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AmitriptylineHalofantrine
Critical

Drug-Drug Interactions

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AmitriptylineHalofantrine
Critical
How does the drug interact with Amicalm-10 Tablet:
Combining Amicalm-10 Tablet and Halofantrine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amicalm-10 Tablet with Halofantrine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Amicalm-10 Tablet:
Using Amicalm-10 Tablet together with Procarbazine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Procarbazine and Amicalm-10 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amicalm-10 Tablet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amicalm-10 Tablet:
Using Amicalm-10 Tablet together with Safinamide can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Safinamide and Amicalm-10 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amicalm-10 Tablet. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amicalm-10 Tablet:
Coadministration of Amicalm-10 Tablet and Cisapride may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amicalm-10 Tablet with Cisapride may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineMesoridazine
Critical
How does the drug interact with Amicalm-10 Tablet:
Coadministration of Amicalm-10 Tablet and Mesoridazine may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amicalm-10 Tablet with Mesoridazine may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Amicalm-10 Tablet:
Combining Amicalm-10 Tablet and Dronedarone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amicalm-10 Tablet with Dronedarone may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Amicalm-10 Tablet:
The combination of Amicalm-10 Tablet and Potassium chloride may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of Amicalm-10 Tablet and Potassium chloride is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.
Critical
How does the drug interact with Amicalm-10 Tablet:
Combining Amicalm-10 Tablet and Bepridil may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amicalm-10 Tablet with Bepridil may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Amicalm-10 Tablet:
Co-administration of Amicalm-10 Tablet together with Selegiline can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a mood stabilizer).

How to manage the interaction:
Although using Selegiline and Amicalm-10 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Amicalm-10 Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineSaquinavir
Critical
How does the drug interact with Amicalm-10 Tablet:
Combining Amicalm-10 Tablet and Saquinavir may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amicalm-10 Tablet with Saquinavir may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGComplications and ill-defined descriptions of heart disease
Severe
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGAcute myocardial infarction
Severe

Drug-Diseases Interactions

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AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGComplications and ill-defined descriptions of heart disease
Severe
How does the disease interact with Amicalm-10 Tablet:
Tricyclic and tetracyclic antidepressants (TCAs) may cause the orthostatic hypotension, reflex tachycardia, syncope, and dizziness, particularly during initiation of therapy.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of heart illness as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden low blood pressure, dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGAcute myocardial infarction
Severe
How does the disease interact with Amicalm-10 Tablet:
The use of tricyclic antidepressants is contraindicated in patients with acute myocardial infarction.

How to manage the interaction:
Amicalm-10 Tablet therapy is not recommended in patients with a history of heart illness as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden low blood pressure, dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGComplications and ill-defined descriptions of heart disease
Severe
How does the disease interact with Amicalm-10 Tablet:
Tricyclic antidepressants should be used with extremely caution in patients with cardiovascular disease because of the possibility of fluctuations in the blood pressure, arrhythmias, conduction defects, tachycardia, myocardial infarction and stroke.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of heart illness as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden fluctuating blood pressure, dizziness, lightheadedness, palpitations, abnormal heart rates, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGDepressive episode
Severe
How does the disease interact with Amicalm-10 Tablet:
Tricyclic antidepressants should be discontinued because the suicidal thoughts have been reported.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of depression or anxiety as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden low blood pressure, dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGConvulsions, not elsewhere classified
Severe
How does the disease interact with Amicalm-10 Tablet:
Tricyclic antidepressants (TCAs), can lower the seizure threshold and trigger seizures. These drugs should be used with extreme caution in patients with a history of seizures, or other predisposing factors, such as head trauma, CNS abnormalities, and alcoholism.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of seizures, head trauma, alcohol or drug withdrawal syndrome as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden low blood pressure, dizziness, lightheadedness, slurred speech, decreased movement or coordination, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGAbnormality of white blood cells, not elsewhere classified
Moderate
How does the disease interact with Amicalm-10 Tablet:
The use of tricyclic and tetracyclic antidepressants (TCAs) have been reported with bone marrow suppression. Leukopenia, agranulocytosis, thrombocytopenia, anemia, eosinophilia, purpura, and pancytopenia.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of blood illness as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden low blood pressure, dizziness, lightheadedness, fainting, shortness of breath, rapid heartbeat, or Paleness of skin, lips and nails contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGType 1 diabetes mellitus
Moderate
How does the disease interact with Amicalm-10 Tablet:
Both elevation and lowering of blood sugar levels have been reported with the use of some tricyclic antidepressants (TCAs).

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in diabetic patients as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, unexplained sweating, shortness of breath, rapid heartbeat, increased urine output, or numb hands and feet contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGAcute renal failure
Moderate
How does the disease interact with Amicalm-10 Tablet:
TCAs should be administered cautiously in patients with renal impaired or hepatic function. Dosage adjustments is necessary.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of kidney illness as it is excreted through the kidneys, which can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, unexplained sweating, shortness of breath, rapid heartbeat, increased urine output, or numb hands and feet contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGSchizophrenia
Moderate
How does the disease interact with Amicalm-10 Tablet:
Tricyclic antidepressants (TCAs) should be administered caution in patients with schizophrenia, bipolar disorder, or a history of mania.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of psychiatric illness as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, slurred speech, shortness of breath, rapid heartbeat, or disorganized movement or coordination contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGDystonia
Moderate
How does the disease interact with Amicalm-10 Tablet:
Tricyclic and tetracyclic antidepressants (TCAs) should not be used in patients with tardive dyskinesia.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of movement disorder as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, slurred speech, shortness of breath, rapid heartbeat, or disorganized movement or coordination contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGMental and behavioural disorders due to use of alcohol
Moderate
How does the disease interact with Amicalm-10 Tablet:
Tricyclic antidepressants can enhance the response to alcohol. In patients who may use alcohol excessively, it should be borne in mind that the potentiation may increase the danger inherent in any suicide attempt or overdosage.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of excessive alcohol consumption as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, slurred speech, shortness of breath, palpitations, or rapid heartbeat contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGBipolar affective disorder
Moderate
How does the disease interact with Amicalm-10 Tablet:
Patients with depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder prior to initiating treatment with a tricyclic antidepressant.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of psychiatric illness as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden mood changes, dizziness, lightheadedness, fainting, confusion, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGGlaucoma
Moderate
How does the disease interact with Amicalm-10 Tablet:
Tricyclic antidepressants should be used with caution in patients with anatomically narrow angle or history of glaucoma.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of vision illness as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience eye pain, red eye, blurred vision, headache, dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGOther disorders of pancreatic internal secretion
Moderate
How does the disease interact with Amicalm-10 Tablet:
Tricyclic antidepressants should be used with caution in patients with hypoglycemia, hyperglycemia or diabetes. Monitoring sugar levels is recommended.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of pancreatic illness such as low or high sugar levels, as this can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, sweating, paleness, increased thirst, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGAlcoholic liver disease
Moderate
How does the disease interact with Amicalm-10 Tablet:
tricyclic antidepressants should be used with caution in patients with liver or renal disease, as these drugs are metabolized and excreted through the liver and kidneys.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of liver illness as it is metabolized in the liver, which can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, confusion, fainting, headache, shortness of breath, yellowing of eyes and skin, or rapid heartbeat contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGOther disorders of thyroid
Moderate
How does the disease interact with Amicalm-10 Tablet:
tricyclic antidepressants should be administered with caution in patients with hyperthyroid.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history of thyroid illness as it can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, confusion, fainting, headache, shortness of breath, or rapid heartbeat contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMITRIPTYLINE-25MG+CHLORDIAZEPOXIDE-30MGRetention of urine
Moderate
How does the disease interact with Amicalm-10 Tablet:
anticholinergic properties of tricyclic antidepressants should be administered with caution in patients with urinary retention.

How to manage the interaction:
Amicalm-10 Tablet therapy is generally avoided in patients with a history or risk of urinary retention or low urine output as it can worsen the condition. It can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, confusion, fainting, headache, shortness of breath, or rapid heartbeat contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • VENLAFAXINE
  • GABAPENTIN
  • PREGABALIN
  • TOPIRAMATE
  • LEVOTHYROXINE SODIUM
  • ALPRAZOLAM
  • LORAZEPAM
  • FLUTICASONE+SALMETEROL
  • FUROSEMIDE
  • MORPHINE

Habit Forming

Yes

Special Advise

  • Do not stop taking Amicalm-10 Tablet on your own; sudden stopping of Amicalm-10 Tablet may cause withdrawal symptoms. Consult your doctor if you have any concerns, the doctor may reduce the dose gradually.
  • Consult your doctor immediately if you develop any suicidal thoughts.
  • Women of childbearing age should use effective contraception while taking Amicalm-10 Tablet .

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products and certain fruits and vegetables help in the proper maintenance of neurotransmitters.
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improving mood, boosting self-esteem and providing restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

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