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Alcohol
Caution
Alcohol may lower your blood pressure. Limit or avoid consuming alcohol while on treatment with Amlosafe-LS 5/5 Tablet is advisable.
Pregnancy
Unsafe
Lisinopril in Amlosafe-LS 5/5 Tablet is a pregnancy D category drug and is not recommended during pregnancy since it causes harmful effects on the developing foetus. However, it is advised to seek medical advice before using Amlosafe-LS 5/5 Tablet if you plan to conceive or pregnant.
Breast Feeding
Caution
There are limited studies on how Amlosafe-LS 5/5 Tablet affects breastfed infants. However, Amlodipine in Amlosafe-LS 5/5 Tablet passes into the breast milk during breastfeeding. Please consult your doctor before using Amlosafe-LS 5/5 Tablet if you are a lactating mother.
Driving
Caution
Amlosafe-LS 5/5 Tablet may cause side effects from lowering blood pressure, such as dizziness or tiredness. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.
Liver
Caution
Let your doctor know if you have any history of liver diseases before using Amlosafe-LS 5/5 Tablet . Your doctor may adjust the dose based on your condition.
Kidney
Caution
Let your doctor know if you have any history of kidney diseases before using Amlosafe-LS 5/5 Tablet . Amlosafe-LS 5/5 Tablet is primarily eliminated by the kidney and can be accumulated in patients with renal impairment. Your doctor may adjust the dose based on your condition.
Children
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Amlosafe-LS 5/5 Tablet is not recommended for children as efficacy and safety have not been established.
Product Substitutes
Drug-Drug Interactions
Drug-Drug Interactions
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Using Amlosafe-LS 5/5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Amlosafe-LS 5/5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Combining Aliskiren with Amlosafe-LS 5/5 Tablet can increase the potassium levels in the blood.
How to manage the interaction:
Although taking Aliskiren and Amlosafe-LS 5/5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms including weakness, tiredness, confusion, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
Using Amlosafe-LS 5/5 Tablet and rifabutin together may lower Amlosafe-LS 5/5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although there is an interaction between Amlosafe-LS 5/5 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
Taking simvastatin with Amlosafe-LS 5/5 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).
How to manage the interaction:
Although taking Amlosafe-LS 5/5 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
Coadministration of Ceritinib together with Amlosafe-LS 5/5 Tablet can slow heart rate and increase the risk of an irregular heart rhythm.
How to manage the interaction:
Although there is an interaction between Amlosafe-LS 5/5 Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
Co-administration of Tizanidine and Amlosafe-LS 5/5 Tablet can increase the risk or severity of developing side effects like low blood pressure.
How to manage the interaction:
Although co-administration of Amlosafe-LS 5/5 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
Coadministration of Amlosafe-LS 5/5 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.
How to manage the interaction:
Taking Nitisinone with Amlosafe-LS 5/5 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
Using Amlosafe-LS 5/5 Tablet and phenytoin together may drastically lower Amlosafe-LS 5/5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although Amlosafe-LS 5/5 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Using Amlosafe-LS 5/5 Tablet and primidone together may lower Amlosafe-LS 5/5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of Amlosafe-LS 5/5 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Co-administration of Amlosafe-LS 5/5 Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).
How to manage the interaction:
There may be a possibility of interaction between Amlosafe-LS 5/5 Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
Drug-Food Interactions
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Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Taking Amlosafe-LS 5/5 Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Amlosafe-LS 5/5 Tablet.
Drug-Diseases Interactions
Drug-Diseases Interactions
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