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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

AMOXYCILLIN-500MG

Manufacturer/Marketer :

Auspharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

Therapeutic Class

Other Info - AMO0215

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About Amoxi 500 Capsule

Uses of Amoxi 500 Capsule

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Amoxi 500 Capsule

Drug Warnings

Drug-Drug Interactions

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AmoxicillinBCG vaccine
Severe

Drug-Drug Interactions

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AmoxicillinBCG vaccine
Severe
How does the drug interact with Amoxi 500 Capsule:
Co-administration of BCG vaccine with Amoxi 500 Capsule may reduce the effect of BCG vaccine.

How to manage the interaction:
If you are about to receive BCG vaccine, inform the doctor that you are taking Amoxi 500 Capsule. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Amoxi 500 Capsule:
Co-administration of methotrexate with Amoxi 500 Capsule can increase the levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Amoxi 500 Capsule, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with Amoxi 500 Capsule:
Co-administration of Amoxi 500 Capsule with doxycycline may reduce the therapeutic effect of Amoxi 500 Capsule.

How to manage the interaction:
Although there is a possible interaction between Amoxi 500 Capsule and Doxycycline, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
AmoxicillinCholera, live attenuated
Severe
How does the drug interact with Amoxi 500 Capsule:
Co-administration of Amoxi 500 Capsule and Cholera, live attenuated may reduce the activity of the vaccine.

How to manage the interaction:
If you are currently being treated with Amoxi 500 Capsule or have been treated within the last 14 days, talk to your doctor before receiving cholera vaccine, live. Do not discontinue the medication without consulting a doctor.
AmoxicillinZalcitabine
Severe
How does the drug interact with Amoxi 500 Capsule:
Co-administration of Amoxi 500 Capsule and Zalcitabine can be decreased when combined with Amoxi 500 Capsule.

How to manage the interaction:
There may be a possibility of interaction between Zalcitabine and Amoxi 500 Capsule, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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AMOXYCILLIN-500MGUlcerative colitis
Severe
AMOXYCILLIN-500MGInfectious mononucleosis
Moderate

Drug-Diseases Interactions

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AMOXYCILLIN-500MGUlcerative colitis
Severe
How does the disease interact with Amoxi 500 Capsule:
Nearly all antibacterial medications have been associated with Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis, which can range in severity from mild diarrhoea to deadly colitis. Lincomycin and clindamycin are typically to blame. Antibacterial treatment disrupts the colon's normal flora, promoting the growth of C. difficile, whose toxins A and B contribute to the emergence of CDAD.

How to manage the interaction:
Amoxi 500 Capsule should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation in the large intestine) and pseudomembranous colitis (generally characterized by severe, persistent diarrhoea and severe abdominal cramps and sometimes associated with the passage of blood and mucus).
AMOXYCILLIN-500MGInfectious mononucleosis
Moderate
How does the disease interact with Amoxi 500 Capsule:
When given an aminopenicillin antibiotic for mononucleosis, patients may experience a pruritic, erythematous, maculopapular skin rash. Usually, the rash self-limits and goes away a few days after the offending chemical is stopped. The underlying mechanism has been suggested to be a changed drug metabolism or an immune-mediated process unrelated to drug hypersensitivity. Patients with mononucleosis shouldn't receive treatment with antibiotics containing aminopenicillin.

How to manage the interaction:
Amoxi 500 Capsule should not be used in patients with mononucleosis (contagious infection caused by virus) as it may cause skin rash.
AMOXYCILLIN-500MGType 1 diabetes mellitus
Moderate
How does the disease interact with Amoxi 500 Capsule:
When utilising Clinitest®, Benedict's Solution, or Fehling's Solution to test for the presence of glucose in urine, high ampicillin concentrations in the urine may provide false-positive results. It is advised to use glucose tests based on enzymatic glucose oxidase reactions,as this effect may also occur with Amoxi 500 Capsule.

How to manage the interaction:
High urine concentrations of Amoxi 500 Capsule may result in false-positive reactions when testing for the presence of glucose in urine using Benedict's Solution or Fehling's Solution. Hence, it is recommended to use glucose tests based on enzymatic glucose oxidase reactions.
AMOXYCILLIN-500MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Amoxi 500 Capsule:
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in some situations, as metabolites as well. In patients with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise, and their half-lives may be prolonged. According to the individual product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during prolonged and/or high-dose therapy because these medicines have occasionally been linked to nephrotoxicity and changes in renal function.

How to manage the interaction:
Dose adjustments may be required in patients with kidney impairment. Kidney function tests should be performed at regular intervals during prolonged and/or high-dose therapy since nephrotoxicity (rapid deterioration in kidney function) and alterations in kidney function have occasionally been associated with the use of Amoxi 500 Capsule.

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