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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Composition :

AMPHOTERICIN B-50MG

Manufacturer/Marketer :

Bharat Serums and Vaccines Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIFUNGALS

Country of origin

INDIA

Manufacturer/Marketer address

17th Floor, Hoechst House, Nariman Point, Mumbai ? 400 021, Maharashtra, India.
Other Info - AMP0125

Author Details

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FAQs

Amphomul 50 Injection contains Amphotericin B, an antifungal that works by damaging fungal cell membranes, thereby killing fungi.

You are not recommended to take Amphomul 50 Injection with furosemide as co-administration of these medicines may increase the risk of hypokalaemia (low potassium levels in the blood), and in severe cases, it may lead to paralysis, muscle weakness, irregular heart rhythm, difficulty in breathing or swallowing. However, please consult your doctor before taking Amphomul 50 Injection with other medicines.

Amphomul 50 Injection may cause blue lips and skin, probably during infusion or in the initial 2 days of treatment. However, your doctor or nurse may arrange certain simple treatments to control such adverse effects.

Yes, a test dose of Amphomul 50 Injection may be given in smaller amounts before starting the treatment to check if you are sensitive to any of the ingredients.

You are recommended to use Amphomul 50 Injection for as long as your doctor has prescribed it. However, the usual treatment is for a minimum of 14 days. Please consult a doctor if you experience any difficulty while taking Amphomul 50 Injection.

Amphomul 50 Injection is not used to treat viral infections. Amphomul 50 Injection is an antifungal that kills fungi and is used to treat severe fungal infections.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

The interaction of Amphomul 50 Injection with alcohol is unknown. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Consult your doctor

Amphomul 50 Injection is a Category B pregnancy drug and is given to a pregnant woman if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning pregnancy.

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Breast Feeding

Consult your doctor

It is unknown whether Amphomul 50 Injection is excreted in human milk. If you are breastfeeding, inform your doctor before receiving this injection.

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Driving

Caution

Avoid driving after taking Amphomul 50 Injection as it may affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Inform your doctor if you have a history of liver diseases/conditions before receiving Amphomul 50 Injection.

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Kidney

Consult your doctor

Inform your doctor if you have a history of kidney diseases/conditions before receiving Amphomul 50 Injection.

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Children

Caution

Amphomul 50 Injection is not recommended for children below one month as the safety and effectiveness were not established.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

About Amphomul 50 Injection

Amphomul 50 Injection belongs to a class of medication called 'antifungal' used to treat severe fungal infections like leishmaniasis. A fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. 

Amphomul 50 Injection contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Amphomul 50 Injection is given by a doctor or nurse. In some cases, you may experience fever, chills, irregular heartbeat, high or low blood pressure, breathing problems, nausea, vomiting, headache, shaking, muscle cramps or pain. Most of these side effects of Amphomul 50 Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Amphomul 50 Injection or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Amphomul 50 Injection. Amphomul 50 Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphomul 50 Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain or difficulty in breathing, or encephalopathy (a brain disease which may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help.

Uses of Amphomul 50 Injection

Severe fungal infections

Medicinal Benefits Mweb

Medicinal Benefits

Amphomul 50 Injection contains Amphotericin B, an antifungal used to treat severe fungal infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Amphomul 50 Injection damages fungal cell membranes and kills fungi. Amphomul 50 Injection is used to treat infections such as blood infection with candida, cryptococcus, fusarium, zygomycetes, aspergillus, coccidiodes or blastomycetes, or cryptococcal meningitis (inflammation of the brain).

Directions for Use

Amphomul 50 Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Amphomul 50 Injection

  • Fever
  • Chills
  • Irregular heartbeat
  • High or low blood pressure
  • Breathing problems
  • Nausea
  • Vomiting
  • Headache
  • Shaking
  • Muscle cramps or pain

Drug Warnings

If you are allergic to Amphotericin B or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Amphomul 50 Injection. Amphomul 50 Injection is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphomul 50 Injection as it may affect your ability to drive. If you experience severe adverse effects such as chest pain, difficulty breathing, or encephalopathy (a brain disease that may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help. If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Amphomul 50 Injection.

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical
Amphotericin bIotalamic acid
Severe

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical
How does the drug interact with Amphomul 50 Injection:
Taking Amphomul 50 Injection and streptozocin together can enhance kidney injury and can cause damage to the ear.

How to manage the interaction:
Taking Streptozocin with Amphomul 50 Injection is not recommended as it can result in an interaction, it can be taken if a doctor has advised it.
Amphotericin bIotalamic acid
Severe
How does the drug interact with Amphomul 50 Injection:
Coadministration of Amphomul 50 Injection and Iotalamic acid may decrease the excretion rate of Iothalamic acid which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Amphomul 50 Injection and Iotalamic acid, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Amphomul 50 Injection:
Coadministration of Amphomul 50 Injection and Iodamide may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Amphomul 50 Injection and Iodamide, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much you pee. If you notice any changes, let the doctor know. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amphomul 50 Injection:
Tenofovir alafenamide can cause kidney problems and taking it with amikacin, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Amphomul 50 Injection and Tenofovir alafenamide, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Amphomul 50 Injection:
Taking tacrolimus with Amphomul 50 Injection can increase the risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Amphomul 50 Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Amphomul 50 Injection:
Coadministration of Amphomul 50 Injection and Iodixanol can cause higher levels of Iodixanol in the blood by reducing its excretion rate.

How to manage the interaction:
There may be a possibility of interaction between Amphomul 50 Injection and Iodixanol, but it can be taken if prescribed by a doctor. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let the doctor know right away. These changes could be a sign of different health issues, like problems with your kidneys, diabetes, or dehydration. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble breathing. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Amphomul 50 Injection:
Coadministration of Amphomul 50 Injection and Iohexol may increase the risk of kidney problems.

How to manage the interaction:
Although taking Amphomul 50 Injection and Iohexol together can cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amphomul 50 Injection:
Coadministration of Amphomul 50 Injection and Temsirolimus may increase the risk of kidney problem.

How to manage the interaction:
Although taking Amphomul 50 Injection and Temsirolimus together can cause an interaction, it can be taken if a doctor has suggested it. If you experience any changes like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not discontinue any medications without consulting the doctor.
Severe
How does the drug interact with Amphomul 50 Injection:
Coadministration of Amphomul 50 Injection and Iomeprol may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Amphomul 50 Injection with Iomeprol can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you experience any changes, like peeing more or less than usual, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Amphomul 50 Injection:
Using foscarnet together with Amphomul 50 Injection can cause serious side effects to the kidneys. Using these drugs together can also increase the risks of seizures (fits) and an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Amphomul 50 Injection and Foscarnet, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: seizures, an irregular heart rhythm, feeling sick, swelling, sudden weight gain or loss, severe pain in your upper stomach that spreads, strong heartbeats, feeling dizzy, or chest pain. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ZIDOVUDINE
  • CICLOSPORIN
  • FLUCYTOSINE
  • FUROSEMIDE
  • METHOTREXATE

Habit Forming

No

Special Advise

  • Regular blood tests are recommended while taking Amphomul 50 Injection to monitor blood, liver or kidney functioning and potassium levels.

Diet & Lifestyle Advise

  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt and long pants while doing outdoor activities such as yard work, gardening or visiting wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Amphomul 50 Injection Substitute

Always consult your doctor before taking any new medications and supplements

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