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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS

Composition :

APIXABAN-5MG

Manufacturer/Marketer :

Msn Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - API0122

Author Details

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About Apiban 5 Tablet

Uses of Apiban 5 Tablet

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of Apiban 5 Tablet

Drug Warnings

Drug-Drug Interactions

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ApixabanDefibrotide
Critical

Drug-Drug Interactions

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ApixabanDefibrotide
Critical
How does the drug interact with Apiban 5 Tablet:
Coadministration of Defibrotide and Apiban 5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Defibrotide and Apiban 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Apiban 5 Tablet:
Mifepristone and Apiban 5 Tablet co-administration have been associated with more severe vaginal bleeding in women.

How to manage the interaction:
Taking Apiban 5 Tablet with Mifepristone together is not generally recommended as it may lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience persistent, excessive bleeding, consult the doctor. Without consulting a doctor, never stop taking any medication.
ApixabanEnzalutamide
Severe
How does the drug interact with Apiban 5 Tablet:
Apiban 5 Tablet's blood levels can be considerably lowered by taking it along with Enzalutamide. This might reduce the Apiban 5 Tablet's ability to treat and prevent blood clots.

How to manage the interaction:
Although the Co-administration of Enzalutamide and Apiban 5 Tablet can possibly lead to an interaction, they can be taken in case a doctor advises it to. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Apiban 5 Tablet:
Combining Ipilimumab and Apiban 5 Tablet may raise the risk of stomach bleeding and ulcers.

How to manage the interaction:
Even though there is an interaction between Apiban 5 Tablet and Ipilimumab, they can be taken if a doctor prescribes it. If you experience potential gastrointestinal injury symptoms like abdominal pain, bloating, dizziness, lightheadedness, loss of hunger, nausea, vomiting (especially with either dry or fresh blood that looks like coffee grounds), and red or black stool, you should see a doctor right away. Without consulting a doctor, never stop taking any medication.
ApixabanRifapentine
Severe
How does the drug interact with Apiban 5 Tablet:
Apiban 5 Tablet's blood levels can be considerably lowered by taking it along with Rifapentine.

How to manage the interaction:
Although Co-administration of Rifapentine and Apiban 5 Tablet can lead to an interaction, they can be taken in case a doctor advises it to. Rifapentine makes Apiban 5 Tablet less effective in treating and preventing blood clots. Never discontinue taking a medication without consulting a doctor.
ApixabanTelaprevir
Severe
How does the drug interact with Apiban 5 Tablet:
Telaprevir may significantly increase the blood levels of Apiban 5 Tablet. This can increase the risk of serious bleeding complications.

How to manage the interaction:
Even though combining Telaprevir and Apiban 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Apiban 5 Tablet:
Coadministration of Dasatinib and Apiban 5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Dasatinib and Apiban 5 Tablet may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like dizziness; red or black, tarry stools; severe headache; and weakness. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Apiban 5 Tablet:
Combining deferasirox and Apiban 5 Tablet may raise the risk of stomach bleeding and ulcers.

How to manage the interaction:
Even though there is an interaction between Apiban 5 Tablet and Deferasirox, they can be taken if a doctor prescribes it. If you experience potential gastrointestinal injury symptoms like abdominal pain, bloating, dizziness, lightheadedness, loss of hunger, nausea, vomiting (especially with either dry or fresh blood that looks like coffee grounds), and red or black stool, consult a doctor. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Apiban 5 Tablet:
Mefenamic acid and Apiban 5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Mefenamic acid and Apiban 5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without first consulting your doctor, never stop taking any medications.
How does the drug interact with Apiban 5 Tablet:
Coadministration of Warfarin and Apiban 5 Tablet may raise the risk of bleeding.

How to manage the interaction:
Even though combining Warfarin and Apiban 5 Tablet may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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APIXABAN-5MGHaemorrhage, not elsewhere classified
Severe
APIXABAN-5MGHepatic failure, not elsewhere classified
Moderate

Drug-Diseases Interactions

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APIXABAN-5MGHaemorrhage, not elsewhere classified
Severe
How does the disease interact with Apiban 5 Tablet:
Factor Xa inhibitors should not be used in individuals who have active pathological bleeding since they raise the risk of bleeding and have the potential to result in serious or fatal haemorrhages. Factor Xa inhibitors should only be prescribed with caution to patients who are at a higher risk of bleeding, such as those who are undergoing procedures where bleeding could result in life-threatening consequences.

How to manage the interaction:
Apiban 5 Tablet therapy is not recommended for patients with a history of bleeding disorder since it can worsen the condition, which can be fatal. It can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
APIXABAN-5MGHepatic failure, not elsewhere classified
Moderate
How does the disease interact with Apiban 5 Tablet:
In individuals with moderate or severe liver impairment (Child-Pugh B or C), the use of factor Xa inhibitors (including Apiban 5 Tablet and edoxaban) is not advised because these patients may have intrinsic coagulation problems.

How to manage the interaction:
Apiban 5 Tablet therapy is generally avoided in patients with a history of liver diseases since it can worsen the condition, which can be fatal. It can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, Skin and eyes that appear yellowish, abdominal pain and swelling, dizziness, lightheadedness, red or black tarry stools, dark urine, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
APIXABAN-5MGNonrheumatic aortic valve disorders
Moderate
How does the disease interact with Apiban 5 Tablet:
Patients who have artificial heart valves shouldn't use some factor Xa inhibitors, such as Apiban 5 Tablet, edoxaban, and rivaroxaban, as their safety and effectiveness have not been proven in this population.

How to manage the interaction:
Apiban 5 Tablet therapy is generally avoided in patients with a history of heart disease since it can worsen the condition, which can be fatal. It can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, palpitations, chest pain or discomfort, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
APIXABAN-5MGOther coagulation defects
Moderate
How does the disease interact with Apiban 5 Tablet:
In individuals with antiphospholipid syndrome (APS), direct-acting oral anticoagulants such as factor Xa inhibitors and some thrombin inhibitors like dabigatran are not advised. Increased rates of recurrent thrombotic events have been linked to the use of these medications, particularly in individuals with triple-positive APS.

How to manage the interaction:
Apiban 5 Tablet therapy is generally avoided in patients with a history of bleeding disorder since it can worsen the condition, which can be fatal. It can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, dark urine, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

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