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Prescription drugWhats That
Composition :
AMOXYCILLIN-250MG
Manufacturer/Marketer :
Ajanta Pharma Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
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Alcohol
Caution
Do not drink too much while taking this medicine. Drinking a lot of alcohol may more likely to drowsiness, dizziness or sleepiness side effects.
Pregnancy
Caution
Apkolin 250 Capsule is a pregnancy category B drug. So, Apkolin 250 Capsule can be safely taken by pregnant women if prescribed by the doctor.
Breast Feeding
Safe if prescribed
Can safely give Apkolin 250 Capsule to breastfeeding mothers.
Driving
Caution
You may have side effects like dizziness after taking Apkolin 250 Capsule that may make you unfit to drive. So, it is advisable not to drive or operate machinery until you are feeling well.
Liver
Safe if prescribed
Apkolin 250 Capsule can be safely taken in case of liver disease if prescribed by the doctor. Your doctor will weigh the benefits and any potential risks before prescribing Apkolin 250 Capsule.
Kidney
Caution
Take Apkolin 250 Capsule with caution if you have severe kidney disease. Your doctor may reduce the dose of Apkolin 250 Capsule in patients with severe renal impairment (GFR less than 30 mL/min).
Children
Safe if prescribed
Can be Apkolin 250 Capsule safely to children, dose to be adjusted and recommended by a child specialist only.
Product Substitutes
Drug-Drug Interactions
Severe
AmoxicillinBCG vaccine
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Apkolin 250 Capsule:
Co-administration of Apkolin 250 Capsule with doxycycline may reduce the therapeutic effect of Apkolin 250 Capsule.
How to manage the interaction:
Although there is a possible interaction between Apkolin 250 Capsule and Doxycycline, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
Co-administration of Apkolin 250 Capsule with doxycycline may reduce the therapeutic effect of Apkolin 250 Capsule.
How to manage the interaction:
Although there is a possible interaction between Apkolin 250 Capsule and Doxycycline, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
AmoxicillinBCG vaccine
Severe
How does the drug interact with Apkolin 250 Capsule:
Co-administration of BCG vaccine with Apkolin 250 Capsule may reduce the effect of BCG vaccine.
How to manage the interaction:
If you are about to receive BCG vaccine, inform the doctor that you are taking Apkolin 250 Capsule. Do not discontinue the medication without consulting a doctor.
Co-administration of BCG vaccine with Apkolin 250 Capsule may reduce the effect of BCG vaccine.
How to manage the interaction:
If you are about to receive BCG vaccine, inform the doctor that you are taking Apkolin 250 Capsule. Do not discontinue the medication without consulting a doctor.
AmoxicillinCholera, live attenuated
Severe
How does the drug interact with Apkolin 250 Capsule:
Co-administration of Apkolin 250 Capsule and Cholera, live attenuated may reduce the activity of the vaccine.
How to manage the interaction:
If you are currently being treated with Apkolin 250 Capsule or have been treated within the last 14 days, talk to your doctor before receiving cholera vaccine, live. Do not discontinue the medication without consulting a doctor.
Co-administration of Apkolin 250 Capsule and Cholera, live attenuated may reduce the activity of the vaccine.
How to manage the interaction:
If you are currently being treated with Apkolin 250 Capsule or have been treated within the last 14 days, talk to your doctor before receiving cholera vaccine, live. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Apkolin 250 Capsule:
Co-administration of methotrexate with Apkolin 250 Capsule can increase the levels and side effects of methotrexate.
How to manage the interaction:
Although there is a possible interaction between methotrexate and Apkolin 250 Capsule, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
Co-administration of methotrexate with Apkolin 250 Capsule can increase the levels and side effects of methotrexate.
How to manage the interaction:
Although there is a possible interaction between methotrexate and Apkolin 250 Capsule, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
AmoxicillinZalcitabine
Severe
How does the drug interact with Apkolin 250 Capsule:
Co-administration of Apkolin 250 Capsule and Zalcitabine can be decreased when combined with Apkolin 250 Capsule.
How to manage the interaction:
There may be a possibility of interaction between Zalcitabine and Apkolin 250 Capsule, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Co-administration of Apkolin 250 Capsule and Zalcitabine can be decreased when combined with Apkolin 250 Capsule.
How to manage the interaction:
There may be a possibility of interaction between Zalcitabine and Apkolin 250 Capsule, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
AMOXYCILLIN-250MGUlcerative colitis
Severe
AMOXYCILLIN-250MGInfectious mononucleosis
Moderate
Drug-Diseases Interactions
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AMOXYCILLIN-250MGUlcerative colitis
Severe
How does the disease interact with Apkolin 250 Capsule:
Nearly all antibacterial medications have been associated with Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis, which can range in severity from mild diarrhoea to deadly colitis. Lincomycin and clindamycin are typically to blame. Antibacterial treatment disrupts the colon's normal flora, promoting the growth of C. difficile, whose toxins A and B contribute to the emergence of CDAD.
How to manage the interaction:
Apkolin 250 Capsule should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation in the large intestine) and pseudomembranous colitis (generally characterized by severe, persistent diarrhoea and severe abdominal cramps and sometimes associated with the passage of blood and mucus).
Nearly all antibacterial medications have been associated with Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis, which can range in severity from mild diarrhoea to deadly colitis. Lincomycin and clindamycin are typically to blame. Antibacterial treatment disrupts the colon's normal flora, promoting the growth of C. difficile, whose toxins A and B contribute to the emergence of CDAD.
How to manage the interaction:
Apkolin 250 Capsule should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation in the large intestine) and pseudomembranous colitis (generally characterized by severe, persistent diarrhoea and severe abdominal cramps and sometimes associated with the passage of blood and mucus).
AMOXYCILLIN-250MGInfectious mononucleosis
Moderate
How does the disease interact with Apkolin 250 Capsule:
When given an aminopenicillin antibiotic for mononucleosis, patients may experience a pruritic, erythematous, maculopapular skin rash. Usually, the rash self-limits and goes away a few days after the offending chemical is stopped. The underlying mechanism has been suggested to be a changed drug metabolism or an immune-mediated process unrelated to drug hypersensitivity. Patients with mononucleosis shouldn't receive treatment with antibiotics containing aminopenicillin.
How to manage the interaction:
Apkolin 250 Capsule should not be used in patients with mononucleosis (contagious infection caused by virus) as it may cause skin rash.
When given an aminopenicillin antibiotic for mononucleosis, patients may experience a pruritic, erythematous, maculopapular skin rash. Usually, the rash self-limits and goes away a few days after the offending chemical is stopped. The underlying mechanism has been suggested to be a changed drug metabolism or an immune-mediated process unrelated to drug hypersensitivity. Patients with mononucleosis shouldn't receive treatment with antibiotics containing aminopenicillin.
How to manage the interaction:
Apkolin 250 Capsule should not be used in patients with mononucleosis (contagious infection caused by virus) as it may cause skin rash.
AMOXYCILLIN-250MGType 1 diabetes mellitus
Moderate
How does the disease interact with Apkolin 250 Capsule:
When utilising Clinitest®, Benedict's Solution, or Fehling's Solution to test for the presence of glucose in urine, high ampicillin concentrations in the urine may provide false-positive results. It is advised to use glucose tests based on enzymatic glucose oxidase reactions,as this effect may also occur with Apkolin 250 Capsule.
How to manage the interaction:
High urine concentrations of Apkolin 250 Capsule may result in false-positive reactions when testing for the presence of glucose in urine using Benedict's Solution or Fehling's Solution. Hence, it is recommended to use glucose tests based on enzymatic glucose oxidase reactions.
When utilising Clinitest®, Benedict's Solution, or Fehling's Solution to test for the presence of glucose in urine, high ampicillin concentrations in the urine may provide false-positive results. It is advised to use glucose tests based on enzymatic glucose oxidase reactions,as this effect may also occur with Apkolin 250 Capsule.
How to manage the interaction:
High urine concentrations of Apkolin 250 Capsule may result in false-positive reactions when testing for the presence of glucose in urine using Benedict's Solution or Fehling's Solution. Hence, it is recommended to use glucose tests based on enzymatic glucose oxidase reactions.
AMOXYCILLIN-250MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Apkolin 250 Capsule:
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in some situations, as metabolites as well. In patients with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise, and their half-lives may be prolonged. According to the individual product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during prolonged and/or high-dose therapy because these medicines have occasionally been linked to nephrotoxicity and changes in renal function.
How to manage the interaction:
Dose adjustments may be required in patients with kidney impairment. Kidney function tests should be performed at regular intervals during prolonged and/or high-dose therapy since nephrotoxicity (rapid deterioration in kidney function) and alterations in kidney function have occasionally been associated with the use of Apkolin 250 Capsule.
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in some situations, as metabolites as well. In patients with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise, and their half-lives may be prolonged. According to the individual product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during prolonged and/or high-dose therapy because these medicines have occasionally been linked to nephrotoxicity and changes in renal function.
How to manage the interaction:
Dose adjustments may be required in patients with kidney impairment. Kidney function tests should be performed at regular intervals during prolonged and/or high-dose therapy since nephrotoxicity (rapid deterioration in kidney function) and alterations in kidney function have occasionally been associated with the use of Apkolin 250 Capsule.
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