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Genuine Products
Composition :
APREPITANT-205MG
Manufacturer/Marketer :
Oncostar Pharma Pvt Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Drug-Drug Interactions
AprepitantAstemizole
Critical
Critical
Drug-Drug Interactions
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AprepitantAstemizole
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Co-administration with Apree 125 mg/80 mg Combipack Capsule and Astemizole may increase the blood levels of Astemizole.
How to manage the interaction:
Although taking Apree 125 mg/80 mg Combipack Capsule and Astemizole together is not recommended as it can lead to an interaction, it is safe if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor. Astemizole should not be combined with any other medications without a doctor's advice.
Co-administration with Apree 125 mg/80 mg Combipack Capsule and Astemizole may increase the blood levels of Astemizole.
How to manage the interaction:
Although taking Apree 125 mg/80 mg Combipack Capsule and Astemizole together is not recommended as it can lead to an interaction, it is safe if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor. Astemizole should not be combined with any other medications without a doctor's advice.
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Co-administration with Apree 125 mg/80 mg Combipack Capsule and Cisapride may cause irregular heart rhythm.
How to manage the interaction:
Although taking Apree 125 mg/80 mg Combipack Capsule and Cisapride together is not recommended as it can lead to an interaction, it is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
Co-administration with Apree 125 mg/80 mg Combipack Capsule and Cisapride may cause irregular heart rhythm.
How to manage the interaction:
Although taking Apree 125 mg/80 mg Combipack Capsule and Cisapride together is not recommended as it can lead to an interaction, it is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
AprepitantTerfenadine
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Co-administration with Apree 125 mg/80 mg Combipack Capsule and Terfenadine may increase the blood levels of Terfenadine and leads to irregular heartbeat.
How to manage the interaction:
Taking Apree 125 mg/80 mg Combipack Capsule and Terfenadine together is not recommended as it can lead to an interaction. It is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
Co-administration with Apree 125 mg/80 mg Combipack Capsule and Terfenadine may increase the blood levels of Terfenadine and leads to irregular heartbeat.
How to manage the interaction:
Taking Apree 125 mg/80 mg Combipack Capsule and Terfenadine together is not recommended as it can lead to an interaction. It is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Using pimozide together with Apree 125 mg/80 mg Combipack Capsule may significantly increase the blood levels of pimozide. High blood levels of pimozide can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Taking Apree 125 mg/80 mg Combipack Capsule and Pimozide together is not recommended; as it can lead to an interaction, you can take them if your doctor advises you to. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, get immediate medical help. Do not discontinue any medications without consulting a doctor.
Using pimozide together with Apree 125 mg/80 mg Combipack Capsule may significantly increase the blood levels of pimozide. High blood levels of pimozide can increase the risk of an irregular heart rhythm that may be serious.
How to manage the interaction:
Taking Apree 125 mg/80 mg Combipack Capsule and Pimozide together is not recommended; as it can lead to an interaction, you can take them if your doctor advises you to. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, get immediate medical help. Do not discontinue any medications without consulting a doctor.
AprepitantEliglustat
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Apree 125 mg/80 mg Combipack Capsule combined with Eliglustat can considerably raise blood levels of Eliglustat. This raises the possibility of cardiac adverse effects such as abnormal heart rhythm, heart block, and cardiac arrest.
How to manage the interaction:
Taking Apree 125 mg/80 mg Combipack Capsule and Eliglustat together is not recommended as it can lead to an interaction; they can be consumed if prescribed by a doctor. Consult a doctor if you have symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, weak heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Apree 125 mg/80 mg Combipack Capsule combined with Eliglustat can considerably raise blood levels of Eliglustat. This raises the possibility of cardiac adverse effects such as abnormal heart rhythm, heart block, and cardiac arrest.
How to manage the interaction:
Taking Apree 125 mg/80 mg Combipack Capsule and Eliglustat together is not recommended as it can lead to an interaction; they can be consumed if prescribed by a doctor. Consult a doctor if you have symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, weak heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AprepitantFlibanserin
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Using flibanserin together with Apree 125 mg/80 mg Combipack Capsule can significantly increase the blood levels of flibanserin.
How to manage the interaction:
Taking Flibanserin and Apree 125 mg/80 mg Combipack Capsule together is not recommended as it can lead to an interaction; they can be taken if prescribed by a doctor. Consult a doctor if you develop any symptoms, such as extreme sleepiness or low blood pressure, that cause dizziness, lightheadedness, or fainting. To reduce the chance of these side effects, use Flibanserin at bedtime. Do not discontinue any medications without consulting a doctor.
Using flibanserin together with Apree 125 mg/80 mg Combipack Capsule can significantly increase the blood levels of flibanserin.
How to manage the interaction:
Taking Flibanserin and Apree 125 mg/80 mg Combipack Capsule together is not recommended as it can lead to an interaction; they can be taken if prescribed by a doctor. Consult a doctor if you develop any symptoms, such as extreme sleepiness or low blood pressure, that cause dizziness, lightheadedness, or fainting. To reduce the chance of these side effects, use Flibanserin at bedtime. Do not discontinue any medications without consulting a doctor.
AprepitantLomitapide
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Lomitapide blood levels can be significantly increased by combining it with Apree 125 mg/80 mg Combipack Capsule.
How to manage the interaction:
Although using Lomitapide and Apree 125 mg/80 mg Combipack Capsule together may cause an interaction, they can be taken if advised by a doctor. Consult a doctor if you have any of the following symptoms: diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, liver problems causing fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Lomitapide blood levels can be significantly increased by combining it with Apree 125 mg/80 mg Combipack Capsule.
How to manage the interaction:
Although using Lomitapide and Apree 125 mg/80 mg Combipack Capsule together may cause an interaction, they can be taken if advised by a doctor. Consult a doctor if you have any of the following symptoms: diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, liver problems causing fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Using Lurasidone together with Apree 125 mg/80 mg Combipack Capsule may result in significantly higher Lurasidone blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)
How to manage the interaction:
While Lurasidone and Apree 125 mg/80 mg Combipack Capsule may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Using Lurasidone together with Apree 125 mg/80 mg Combipack Capsule may result in significantly higher Lurasidone blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)
How to manage the interaction:
While Lurasidone and Apree 125 mg/80 mg Combipack Capsule may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Coadministration of fentanyl and Apree 125 mg/80 mg Combipack Capsule may significantly increase the blood levels and effects of fentanyl.
How to manage the interaction:
Although co-administration of Apree 125 mg/80 mg Combipack Capsule and Fentanyl can lead to an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, excessive drowsiness, or difficulty breathing. Do not discontinue any medications without consulting your doctor.
Coadministration of fentanyl and Apree 125 mg/80 mg Combipack Capsule may significantly increase the blood levels and effects of fentanyl.
How to manage the interaction:
Although co-administration of Apree 125 mg/80 mg Combipack Capsule and Fentanyl can lead to an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, excessive drowsiness, or difficulty breathing. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Co-administartion of Apree 125 mg/80 mg Combipack Capsule and Ivabradine may significantly increase the blood levels of Ivabradine which can result in excessive slowing of heart rate or other side effects.
How to manage the interaction:
Although there is an interaction between Apree 125 mg/80 mg Combipack Capsule and Ivabradine, it can be taken if prescribed by a doctor. If you have dizziness, tiredness, low blood pressure, heart palpitations, chest pain, or worsening shortness of breath, you should see a doctor. Without consulting a doctor, never stop taking medicines.
Co-administartion of Apree 125 mg/80 mg Combipack Capsule and Ivabradine may significantly increase the blood levels of Ivabradine which can result in excessive slowing of heart rate or other side effects.
How to manage the interaction:
Although there is an interaction between Apree 125 mg/80 mg Combipack Capsule and Ivabradine, it can be taken if prescribed by a doctor. If you have dizziness, tiredness, low blood pressure, heart palpitations, chest pain, or worsening shortness of breath, you should see a doctor. Without consulting a doctor, never stop taking medicines.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
APREPITANT-205MGAlcoholic liver disease
Moderate
Drug-Diseases Interactions
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APREPITANT-205MGAlcoholic liver disease
Moderate
How does the disease interact with Apree 125 mg/80 mg Combipack Capsule:
The liver is primarily responsible for Apree 125 mg/80 mg Combipack Capsule metabolism. Apree 125 mg/80 mg Combipack Capsule was well tolerated in investigations of patients with mild to moderate hepatic impairment (Child-Pugh score 5 to 9), and no clinically significant changes in its pharmacokinetics were seen. As a result, there is no need to change the dosage of Apree 125 mg/80 mg Combipack Capsule in this patient population. Apree 125 mg/80 mg Combipack Capsule should be used with caution in patients with severe hepatic impairment (Child-Pugh score > 9), as there is no clinical or pharmacokinetic data in this population.
How to manage the interaction:
Apree 125 mg/80 mg Combipack Capsule is metabolized by the liver, hence it is usually not recommended in patients with mild to moderate liver disease as it can increase the Apree 125 mg/80 mg Combipack Capsule level in the body. Increased levels can increase the risk and severity of Apree 125 mg/80 mg Combipack Capsule side effects. However, you can take it when advised by your doctor. If you experience headache, fatigue, low appetite, constipation, diarrhea, nausea, and hiccups contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
The liver is primarily responsible for Apree 125 mg/80 mg Combipack Capsule metabolism. Apree 125 mg/80 mg Combipack Capsule was well tolerated in investigations of patients with mild to moderate hepatic impairment (Child-Pugh score 5 to 9), and no clinically significant changes in its pharmacokinetics were seen. As a result, there is no need to change the dosage of Apree 125 mg/80 mg Combipack Capsule in this patient population. Apree 125 mg/80 mg Combipack Capsule should be used with caution in patients with severe hepatic impairment (Child-Pugh score > 9), as there is no clinical or pharmacokinetic data in this population.
How to manage the interaction:
Apree 125 mg/80 mg Combipack Capsule is metabolized by the liver, hence it is usually not recommended in patients with mild to moderate liver disease as it can increase the Apree 125 mg/80 mg Combipack Capsule level in the body. Increased levels can increase the risk and severity of Apree 125 mg/80 mg Combipack Capsule side effects. However, you can take it when advised by your doctor. If you experience headache, fatigue, low appetite, constipation, diarrhea, nausea, and hiccups contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
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