apollo
0
  1. Home
  2. Medicine
  3. Arganat 250Mg/2.5Ml Inf

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

ARGATROBAN-250MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - ARG0081

FAQs

Arganat 250Mg/2.5Ml Inf contains 'Argatroban,' which is a direct thrombin inhibitor. It works by reversibly binding to thrombin, a substance in the blood that causes blood clotting. This prevents the formation of harmful clots in the body.

The clinical assessment and laboratory data are used to diagnose HIT. Primary laboratory diagnostics for HIT include immunologic assays such as an enzyme-linked immunosorbent assay (ELISA) and functional platelet-activation assays such as the serotonin release assay (SRA).

When a person with haemophilia takes the blood-thinning treatment, their body develops antibodies against it, resulting in heparin-induced thrombocytopenia.

Heparin-induced thrombocytopenia (HIT) is triggered by antibodies that recognise complexes between platelet factor 4 (PF4) and heparin or glycosaminoglycan side chains.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
bannner image

Alcohol

Caution

Do not consume alcohol while on treatment with Arganat 250Mg/2.5Ml Inf as it may lead to unpleasant side effects.

bannner image

Pregnancy

Caution

Arganat 250Mg/2.5Ml Inf should not be used in pregnancy unless clearly necessary. If you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Arganat 250Mg/2.5Ml Inf.

bannner image

Breast Feeding

Unsafe

Breastfeeding must be avoided during treatment with Arganat 250Mg/2.5Ml Inf. Discuss with your doctor if you have any concerns.

bannner image

Driving

Caution

Avoid driving or operating machinery while you are on treatment with this medicine.

bannner image

Liver

Caution

Please inform your doctor if you have liver conditions before receiving Arganat 250Mg/2.5Ml Inf. Your doctor may adjust the dose or prescribe a suitable alternative depending on your medical condition.

bannner image

Kidney

Caution

Please inform your doctor if you have liver conditions before receiving Arganat 250Mg/2.5Ml Inf. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

It is not recommended for children as the safety and effectiveness have not been established.

About Arganat 250Mg/2.5Ml Inf

Arganat 250Mg/2.5Ml Inf belongs to the anticoagulant medication class known as a direct thrombin inhibitor. It is used to manage heparin-induced thrombocytopenia (HIT), a rare, life-threatening complication of heparin therapy. Besides this, it works as an anticoagulant in adult patients with or at risk for HIT undergoing percutaneous coronary intervention (PCI).

Arganat 250Mg/2.5Ml Inf contains 'Argatroban,' which is a direct thrombin inhibitor. It works by reversibly binding to thrombin, a substance in the blood that causes blood clotting. This prevents the formation of harmful clots in the body.

Arganat 250Mg/2.5Ml Inf is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. The most common side effects in HIT patients were dyspnea, hypotension, fever, diarrhoea, sepsis, and cardiac arrest. The most common side effects in PCI patients were chest pain, hypotension, back pain, nausea, vomiting and headache. These side effects may vary individually. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking the Arganat 250Mg/2.5Ml Inf, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Arganat 250Mg/2.5Ml Inf is not recommended during pregnancy unless indicated by the doctor. Discontinue nursing or drug, taking into account the importance of the drug to the mother. It is recommended not to consume any alcoholic beverages to rule out any possibility of side effects. Safety and effectiveness have not been established in the paediatric population.

Uses of Arganat 250Mg/2.5Ml Inf

Heparin-Induced thrombocytopenia (HIT)

Medicinal Benefits Mweb

Medicinal Benefits

Arganat 250Mg/2.5Ml Inf contains 'Argatroban,' which is a direct thrombin inhibitor. It works by reversibly binding to thrombin, a substance in the blood that causes blood clotting. This prevents the formation of harmful clots in the body.

Directions for Use

Arganat 250Mg/2.5Ml Inf will be administered by a healthcare professional. Your doctor decides the dose and duration based on your medical condition and response to the treatment.

Side Effects of Arganat 250Mg/2.5Ml Inf

HIT patients:

  • Dyspnea
  • Hypotension
  • Fever
  • Diarrhoea
  • Sepsis
  • Cardiac Arrest

PCI patients:

  • Chest Pain
  • Hypotension
  • Back Pain
  • Nausea
  • Vomiting
  • Headache

Drug Warnings

Inform your doctor about all of your health problems (especially active bleeding), allergic reactions (food or medicine sensitivities), and drugs you are using (especially Thrombolytic agents such as Urokinase) before taking the Arganat 250Mg/2.5Ml Inf. When pregnant, Arganat 250Mg/2.5Ml Inf should not be used unless specifically advised by a physician. So, inform your doctor if you are pregnant or planning to. Discontinue nursing or medicine, taking into account the importance of the drug to the mother. Do not consume any other medications while on therapy unless prescribed by the doctor.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

Login/Sign Up

How does the drug interact with Arganat 250Mg/2.5Ml Inf:
Taking cefdinir with Arganat 250Mg/2.5Ml Inf may lead to increase in the effects of Arganat 250Mg/2.5Ml Inf.

How to manage the interaction:
Although taking Cefdinir and Arganat 250Mg/2.5Ml Inf together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Arganat 250Mg/2.5Ml Inf:
Combining Arganat 250Mg/2.5Ml Inf with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Arganat 250Mg/2.5Ml Inf may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Arganat 250Mg/2.5Ml Inf:
Coadministration of Arganat 250Mg/2.5Ml Inf and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Arganat 250Mg/2.5Ml Inf and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Arganat 250Mg/2.5Ml Inf:
Co-administration of Prasugrel with Arganat 250Mg/2.5Ml Inf can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel with Arganat 250Mg/2.5Ml Inf can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Arganat 250Mg/2.5Ml Inf:
Taking Dabigatran etexilate with Arganat 250Mg/2.5Ml Inf can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Arganat 250Mg/2.5Ml Inf together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Arganat 250Mg/2.5Ml Inf:
Taking clopidogrel together with Arganat 250Mg/2.5Ml Inf can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between clopidogrel and Apixaban, they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding, like feeling dizzy or lightheaded, red or black, sticky stools, or severe headaches. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Arganat 250Mg/2.5Ml Inf:
Taking Arganat 250Mg/2.5Ml Inf with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between fondaparinux and Arganat 250Mg/2.5Ml Inf, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • FONDAPARINUX
  • ENOXAPARIN
  • CLOPIDOGREL
  • RIVAROXABAN

Habit Forming

No

Diet & Lifestyle Advise

  • Consume a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Exercise on a regular basis to keep your body and mind healthy.
  • Avoid chronic stress.
  • Smoking and consuming alcohol should be avoided.
  • To reduce the risk of bleeding, avoid activities such as contact sports and the use of sharp objects such as nail cutters and razors.

Have a query?