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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

APREMILAST-30MG

Manufacturer/Marketer :

Wallace Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Arthlast 30mg Tablet

Arthlast 30mg Tablet belongs to a class of drugs known as phosphodiesterase 4 (PDE4) inhibitors. It is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriatic arthritis is a type of arthritis that some people with psoriasis experience.

Arthlast 30mg Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Arthlast 30mg Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin), and thus, lowers the signs and symptoms of these conditions.

Take Arthlast 30mg Tablet as prescribed by your doctor. You are advised to take Arthlast 30mg Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience diarrhoea, vomiting, nausea, weight loss, and back pain. Most of these side effects of Arthlast 30mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Arthlast 30mg Tablet should not be taken in the conditions like depression as it is getting worse with thoughts of suicide. Before starting Arthlast 30mg Tablet , please inform your doctor if you have any allergy to Arthlast 30mg Tablet and its part. Arthlast 30mg Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Arthlast 30mg Tablet . Arthlast 30mg Tablet does not affect the ability to drive and use machines.

Uses of Arthlast 30mg Tablet

Plaque psoriasis, psoriasis arthritis, and oral ulcers caused by Behcet's disease.

Directions for Use

Take Arthlast 30mg Tablet as prescribed by your doctor. Your doctor determines the dose of the medicine based on your condition. Take Arthlast 30mg Tablet with or without food. Swallow the Arthlast 30mg Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Arthlast 30mg Tablet is used in treating psoriatic arthritis; it decreases pain and swelling and may help improve flexibility in the affected joints. It is also used to treat moderate to severe plaque psoriasis (skin disease causes red, scaly patches to form on some areas of the body) in people who may benefit from medications). It is used to treat ulcers in the mouth in persons with Behcet's syndrome (a disease that results from blood vessel swelling in the body). Arthlast 30mg Tablet works by blocking the action of some chemical messengers responsible for inflammation related to psoriatic arthritis and psoriasis, thus lowering the signs and symptoms of these conditions.

Storage

Store in a cool and dry place away from sunlight
Side effects of Arthlast 30mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • You can take your medicine with meals to lower the chances of getting stomach pain.
  • Avoid foods that are acidic, spicy, sugary, or greasy.
  • Eat foods that are easily digestible such as rice, toast, and bananas.
  • Eat your meals in smaller amounts throughout the day to prevent strain on your stomach and digestion.
  • Drink water or fluids to stay hydrated and prevent stomach upset.
  • Use a heating pad or massage your stomach area.
  • Engage in mild physical activities such as yoga and walking.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

Drug Warnings

Inform your doctor before using Arthlast 30mg Tablet , if you have previously had an allergic reaction (hypersensitivity). Before starting Arthlast 30mg Tablet , please inform your doctor if you have depression and suicidal thoughts. Inform your doctor before taking Arthlast 30mg Tablet if you have severe kidney problems. Inform your doctor while taking Arthlast 30mg Tablet if you lose weight without meaning to. Arthlast 30mg Tablet should not be taken in conditions like severe diarrhoea, nausea, and vomiting. Arthlast 30mg Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Arthlast 30mg Tablet . Patients with rare hereditary galactose intolerance problems, total lactase deficiency or glucose-galactose malabsorption should not take Arthlast 30mg Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Arthlast 30mg Tablet:
Taking Arthlast 30mg Tablet with rifampicin can decrease the blood levels of Arthlast 30mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Arthlast 30mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arthlast 30mg Tablet:
Coadministration of Phenytoin with Arthlast 30mg Tablet may reduce the blood levels of Arthlast 30mg Tablet, which may reduce effectiveness in treatment.

How to manage the interaction:
Although taking Phenytoin and Arthlast 30mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
How does the drug interact with Arthlast 30mg Tablet:
Coadministration of Arthlast 30mg Tablet and Rifabutin may reduce the blood levels of Arthlast 30mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Arthlast 30mg Tablet and Rifabutin, you can take these medicines together if prescribed by a doctor. In case you experience any symptoms, consult a doctor. Do not discontinue any medications without consulting a doctor.
ApremilastEnzalutamide
Severe
How does the drug interact with Arthlast 30mg Tablet:
Coadministration of Enzalutamide with Arthlast 30mg Tablet may reduce the efficacy of treatment.

How to manage the interaction:
Although taking Arthlast 30mg Tablet and Enzalutamide together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arthlast 30mg Tablet:
Coadministration of Arthlast 30mg Tablet with primidone may decrease the blood levels of Arthlast 30mg Tablet, which may make Arthlast 30mg Tablet less effective in treating.

How to manage the interaction:
Although there is an interaction between Primidone and Arthlast 30mg Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arthlast 30mg Tablet:
Coadministration of phenobarbital with Arthlast 30mg Tablet can drastically lower Arthlast 30mg Tablet levels in the blood, making the medicine less effective in treating.

How to manage the interaction:
Although taking phenobarbital with Arthlast 30mg Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastMitotane
Severe
How does the drug interact with Arthlast 30mg Tablet:
Coadministration of Mitotane with Arthlast 30mg Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Arthlast 30mg Tablet and Mitotane together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arthlast 30mg Tablet:
Coadministration of Nevirapine with Arthlast 30mg Tablet may decrease the blood levels of Arthlast 30mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is a possible interaction between Arthlast 30mg Tablet and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastFosphenytoin
Severe
How does the drug interact with Arthlast 30mg Tablet:
Coadministration of Fosphenytoin with Arthlast 30mg Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Fosphenytoin and Arthlast 30mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
ApremilastRifapentine
Severe
How does the drug interact with Arthlast 30mg Tablet:
Rifapentine may decrease the blood levels of Arthlast 30mg Tablet, which may make Arthlast 30mg Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Arthlast 30mg Tablet and Rifapentine together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIPSORIATICS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, Arthlast 30mg Tablet may cause depression as a side effect. The patient may also have suicidal thoughts. Arthlast 30mg Tablet should be avoided in people with a history of depression. In case you develop any of these symptoms, Inform your doctor immediately.

Arthlast 30mg Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on the skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-period treatment and may take about 16 weeks to show an improvement.

Yes, Arthlast 30mg Tablet may cause a reduction in appetite, which may further lead to weight loss. You should monitor your weight frequently while on treatment with Arthlast 30mg Tablet . In case of big weight loss, inform your doctor. Your doctor may consider stopping Arthlast 30mg Tablet .

Rifampicin is an antibiotic. You should not take rifampicin if you are taking Arthlast 30mg Tablet . Rifampicin interferes with the working of Arthlast 30mg Tablet by reducing its levels, making it less effective. As a result, you may not see any recovery after taking Arthlast 30mg Tablet .

As soon as you recall, take the missed dose. If the next dose is approaching, skip the missing dose and resume your regular dosing regimen. Do not duplicate the dose to make up for a missing one.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Special Advise

  • Arthlast 30mg Tablet is a well-tolerated medicine. Mild stomach upset may arise early during the treatment.
  • Monitor your weight repeatedly as Arthlast 30mg Tablet may lead to weight loss.
  • Inform your doctor immediately if you experience new or worsened depression, suicidal thoughts, unexplained weight loss, or other mood changes.

Disease/Condition Glossary

Plaque Psoriasis: It is an inflammatory disease of the skin, leading to red, scaly, thick, itchy, painful patches on your skin and can also affect your nails and scalp. It can happen at any age and is most common in 50 to 69. Internal and external activities, including sunburn, mild trauma, systemic drugs, infections, and stress, can also cause psoriasis.

Psoriatic arthritis: Psoriatic arthritis is an inflammatory disorder of the joints, which affects a few people who have skin from psoriasis.

Behçet’s disease: It is an uncommon type of inflammatory illness that affects many parts of the body. The most common difficulty is mouth ulcers. It is a disease that results in blood vessel swelling in the body.

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