Arthopan 250 mg Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or pain killers used to reduce and relieve pain, redness and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, cervical spondylitis (wear and tear of spinal discs in neck), dysmenorrhea, mild migraine and acute gout (severe pain due to an excess of uric acid) in adult and children. Rheumatoid arthritis is an autoimmune disease in which the immune system of the body attacks its cells and causes damage, thereby causing joint pain with inflammation.

Arthopan 250 mg Tablet is a combination of two drugs: Naproxen (painkiller) and Pantoprazole (antacid). Naproxen is an anti-inflammatory drug that works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances (prostaglandins) that cause pain and swelling. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site decreasing stiffness in joints. It is also used to treat low back pain, strains, and sprains. Naproxen has been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. Hence, it is combined with Pantoprazole (proton pump inhibitors) which reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.

Take Arthopan 250 mg Tablet as prescribed by your doctor. You are advised to take Arthopan 250 mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. You may experience indigestion, stomach pain, constipation, dizziness, nausea, and diarrhea in some cases. Most of these side effects of Arthopan 250 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking this medicine, inform your doctor if you have any known allergy to naproxen, pantoprazole, other NSAIDs or other medications. If you are pregnant or breastfeeding, please inform your doctor before taking Arthopan 250 mg Tablet . Also, inform the doctor if you have a history of heart rhythm problems or ulcers due to painkillers. Patients with age above 65 years, with pre-existing cardiac diseases such as heart failure, hypertension or stroke, gastrointestinal bleeding (due to pain killers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases, or bleeding disorders should use Arthopan 250 mg Tablet only when prescribed by a doctor.

Arthopan 250 mg Tablet is a combination of two drugs, namely: Naproxen is an anti-inflammatory (reduces inflammation) and an analgesic (reduces pain) agent, and Pantoprazole (antacid). Naproxen works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances (prostaglandins) that cause pain and swelling. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site decreasing stiffness in joints. It is also used to treat fibrositis (muscle pain and stiffness), tenosynovitis (swelling of tendons), low back pain, strains and sprains. NSAIDs such as Naproxen have been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. To reduce gastric discomfort and stomach ulceration risk, it is combined with Pantoprazole (a proton pump inhibitor that inhibits gastric acid secretion) to reduce stomach acid production during long-term treatment for people with pre-existing stomach ulcers or for people having a history of developing stomach ulcers while using NSAIDs. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.

Do not take Arthopan 250 mg Tablet if you are allergic to Arthopan 250 mg Tablet . Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as naproxen may increase the risk of heart attack or stroke and stomach ulcers. The risk of developing ulcers is higher if you have a history of ulcers, have bleeding disorders, older in age, alcoholic or have multiple diseases. Elderly patients are at greater risk for gastrointestinal bleeding problems so the doctor can limit their dose. It should not be used by a patient who has undergone recent heart bypass surgery or going to have it. Arthopan 250 mg Tablet is not recommended for pregnant women especially in the third trimester as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Arthopan 250 mg Tablet . Consult your doctor before giving Arthopan 250 mg Tablet to children. Do not take any other NSAIDs for pain relief along with Arthopan 250 mg Tablet unless prescribed. Prolonged intake of PPIs or proton pump inhibitors like pantoprazole may cause brittle bones so intake of Vitamin D and calcium can be additionally given by your doctor while using Arthopan 250 mg Tablet . Do not consume alcohol with Arthopan 250 mg Tablet as it may increase the risk of stomach bleeding or ulcer.

• If you are elderly, a smoker, had stroke previously, or have high blood pressure, diabetes, or high cholesterol, please inform your doctor as these conditions may increase the risk of heart problems.
• Your doctor may monitor liver function and kidney function if you are taking Arthopan 250 mg Tablet for long-term.
• Individuals at risk for osteoporosis-related fractures should receive an adequate intake of calcium and vitamin D.
• Pantoprazole in Arthopan 250 mg Tablet  may interfere with certain laboratory tests (including urine test for tetrahydrocannabinol-THC, and a blood test to find certain tumors), possibly causing false test results. Make sure laboratory personnel and all your doctors know you are using Arthopan 250 mg Tablet .
• Regular monitoring of vitamin B-12, rarely, Pantoprazole in Arthopan 250 mg Tablet have caused vitamin B-12 deficiency. The risk is increased if they are taken Arthopan 250 mg Tablet every day for a long time.