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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

METHOTREXATE-7.5MG

Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

IMMUNOSUPPRESSANTS

Country of origin

India

Manufacturer/Marketer address

Plot No. 45, N.T.M., Sector -26, Chandigarh
Other Info - ART0426

Author Details

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FAQs

Arthrate 7.5 Tablet 4's acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby providing relief from rheumatoid arthritis.

Arthrate 7.5 Tablet 4's works by suppressing the overactive immune system that is responsible for causing psoriasis. Arthrate 7.5 Tablet 4's interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis and psoriatic arthritis.

Diarrhoea might be a side-effect of Arthrate 7.5 Tablet 4's. Stop taking Arthrate 7.5 Tablet 4's and consult your doctor if you have diarrhoea. Do not take anti-diarrheal medicine on your own.

Arthrate 7.5 Tablet 4's can affect egg and sperm production and could lead to birth defects. Women of child-bearing potential and men using Arthrate 7.5 Tablet 4's must use effective contraception while on treatment with Arthrate 7.5 Tablet 4's and for at least six months after stopping the treatment. Arthrate 7.5 Tablet 4's can lead to infertility. Therefore male patients are advised to talk with their doctor regarding the possibility of sperm preservation before starting the treatment with Arthrate 7.5 Tablet 4's.

Arthrate 7.5 Tablet 4's causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Arthrate 7.5 Tablet 4's may cause mouth sores. Stop taking Arthrate 7.5 Tablet 4's and consult your doctor if you have sores in the mouth. Your doctor may recommend folate supplements to treat mouth sores.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Arthrate 7.5 Tablet 4's.

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Pregnancy

Unsafe

Arthrate 7.5 Tablet 4's may cause serious birth defects. It is not recommended to take Arthrate 7.5 Tablet 4's while you are pregnant.

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Breast Feeding

Unsafe

Arthrate 7.5 Tablet 4's passes into breast milk. Avoid breastfeeding whilst on treatment with Arthrate 7.5 Tablet 4's.

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Driving

Caution

Arthrate 7.5 Tablet 4's may cause dizziness and tiredness; do not drive or operate heavy machinery if you experience these symptoms.

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Liver

Caution

Do not take Arthrate 7.5 Tablet 4's if you have chronic liver disease. Please consult your doctor if you have liver impairment before taking Arthrate 7.5 Tablet 4's.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Arthrate 7.5 Tablet 4's.

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Children

Caution

Arthrate 7.5 Tablet 4's should be used with caution in children and only if prescribed by the doctor.

About Arthrate 7.5 Tablet 4's

Arthrate 7.5 Tablet 4's belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis, severe psoriasis, and severe psoriatic arthritis. Arthrate 7.5 Tablet 4's is used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system).

Arthrate 7.5 Tablet 4's contains 'Methotrexate' that works by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Besides this, Arthrate 7.5 Tablet 4's prevents and stops the growth of cancer cells, thereby helps treat cancer. Arthrate 7.5 Tablet 4's treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis.

In some cases, Arthrate 7.5 Tablet 4's may cause common side-effects such as nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, leukopenia (decreased number of white blood cells), and soreness of mouth and lips. You are advised to talk to your doctor if you experience these side effects persistently.

Take Arthrate 7.5 Tablet 4's exactly as prescribed by the doctor; daily intake of Arthrate 7.5 Tablet 4's could lead to serious toxic effects. Do not take Arthrate 7.5 Tablet 4's if you are pregnant or breastfeeding. Arthrate 7.5 Tablet 4's may cause dizziness and fatigue, so drive only if you are alert. Avoid consuming alcohol whilst on treatment with Arthrate 7.5 Tablet 4's. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Inform your doctor about your medications and health condition to rule out any unpleasant side effects/interactions.

Uses of Arthrate 7.5 Tablet 4's

Rheumatoid arthritis, Psoriatic arthritis, Psoriasis, Cancer

Medicinal Benefits Mweb

Medicinal Benefits

Arthrate 7.5 Tablet 4's belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis (arthritis in children), severe psoriasis, and severe psoriatic arthritis. Arthrate 7.5 Tablet 4's helps treat rheumatoid arthritis and psoriatic arthritis by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Arthrate 7.5 Tablet 4's treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis. Arthrate 7.5 Tablet 4's is used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system). Arthrate 7.5 Tablet 4's prevents and stops the growth of cancer cells by interfering with DNA production. Arthrate 7.5 Tablet 4's may also be used to treat inflammatory bowel disease.

Directions for Use

Arthrate 7.5 Tablet 4's should be taken exactly as prescribed by the doctor. Tablet/capsule: Take it one hour after food in the evening or as advised by the doctor. Swallow the tablet/capsule as a whole with a glass of water whilst standing or sitting upright; do not break or chew it. Oral solution: Take the prescribed quantity by mouth using the dosing syringe.

Side Effects of Arthrate 7.5 Tablet 4's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Unusual fatigue
  • Dizziness
  • Headache
  • Loss of appetite
  • Elevated liver enzymes
  • Lowered resistance to infections
  • Tingling sensation
  • Leukopenia (decreased number of white blood cells)
  • Soreness of mouth and lips

Drug Warnings

Do not take Arthrate 7.5 Tablet 4's if you are allergic to any of its contents; if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, chronic liver disease; if you are pregnant or breastfeeding. Talk to your doctor before taking Arthrate 7.5 Tablet 4's if you have/had liver or kidney problems, ulceration in the stomach or bowels, poor general condition, received any vaccinations or if you are due to have any vaccinations, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs. Arthrate 7.5 Tablet 4's may cause dizziness and fatigue, so drive only if you are alert. Take Arthrate 7.5 Tablet 4's exactly as directed by the doctor as it may cause serious problems if not taken in the dose and duration prescribed by the doctor. Stop taking Arthrate 7.5 Tablet 4's and consult your doctor immediately if you have mouth sores, diarrhoea, a fever, dehydration, cough, bleeding, shortness of breath, any signs of infection, or a skin rash.

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
MethotrexateKetorolac
Severe

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
How does the drug interact with Arthrate 7.5 Tablet:
Co-administration of Etretinate with Arthrate 7.5 Tablet may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Etretinate with Arthrate 7.5 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MethotrexateKetorolac
Severe
How does the drug interact with Arthrate 7.5 Tablet:
Coadministration of Arthrate 7.5 Tablet with ketorolac can increase the blood levels and side effects of Arthrate 7.5 Tablet.

How to manage the interaction:
Although there is a interaction between Arthrate 7.5 Tablet and ketorolac, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateFlucytosine
Severe
How does the drug interact with Arthrate 7.5 Tablet:
Combine use of entecavir with Arthrate 7.5 Tablet may increase the effectiveness of everolimus.

How to manage the interaction:
Although there is a possible interaction between everolimus and Arthrate 7.5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without first consulting to your doctor.
MethotrexateTenofovir alafenamide
Severe
How does the drug interact with Arthrate 7.5 Tablet:
Combine use of tenofovir alafenamide with Arthrate 7.5 Tablet may increase the levels or side effects of tenofovir alafenamide.

How to manage the interaction:
Although there is a possible interaction between tenofovir alafenamide and Arthrate 7.5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without consulting your doctor.
MethotrexateEntecavir
Severe
How does the drug interact with Arthrate 7.5 Tablet:
The combined use of entecavir with Arthrate 7.5 Tablet may increase levels of Entecavir, and increase the risk or severity of kidney damage.

How to manage the interaction:
Although there is a possible interaction between entecavir and Arthrate 7.5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateEtodolac
Severe
How does the drug interact with Arthrate 7.5 Tablet:
Co-administration of Arthrate 7.5 Tablet with etodolac can increase the level and effects of Arthrate 7.5 Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Arthrate 7.5 Tablet and etodolac, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateEtanercept
Severe
How does the drug interact with Arthrate 7.5 Tablet:
Co-administration of Arthrate 7.5 Tablet with etanercept can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between etanercept and Arthrate 7.5 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, and pain or burning during urination, Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateDiclofenac
Severe
How does the drug interact with Arthrate 7.5 Tablet:
Co-administration of Arthrate 7.5 Tablet with diclofenac can increase the levels and effects of Arthrate 7.5 Tablet. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Arthrate 7.5 Tablet and diclofenac, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexateNafcillin
Severe
How does the drug interact with Arthrate 7.5 Tablet:
Coadministration of Arthrate 7.5 Tablet with nafcillin can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between nafcillin and Arthrate 7.5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, nausea, vomiting, mouth ulcers, sore throat, body aches, or other flu-like symptoms, consult the doctor.
MethotrexateDeferasirox
Severe
How does the drug interact with Arthrate 7.5 Tablet:
Taking deferasirox with Arthrate 7.5 Tablet may increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between deferasirox and Arthrate 7.5 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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METHOTREXATE-7.5MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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METHOTREXATE-7.5MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine may reduce the effectiveness of Arthrate 7.5 Tablet. Avoid taking caffeine while taking Arthrate 7.5 Tablet. This can increase the risk or severity of side effects.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CELECOXIB
  • ACETAMINOPHEN
  • HYDROCODONE
  • DULOXETINE
  • ETANERCEPT
  • ADALIMUMAB
  • ESOMEPRAZOLE
  • HYDROXYCHLOROQUINE

Habit Forming

No

Special Advise

  • Women of child-bearing age must use effective contraception whilst on treatment with Arthrate 7.5 Tablet 4's and for at least 6 months after the last dose.
  • Male patients are advised to consult their doctor regarding the possibility of sperm preservation before starting the treatment as Arthrate 7.5 Tablet 4's may cause infertility.
  • Arthrate 7.5 Tablet 4's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
  • Your doctor may advise regular blood tests, kidney and liver tests to monitor your condition.
  • If you miss a dose of Arthrate 7.5 Tablet 4's, call your doctor and ask if you should take the missed dose or not.

Diet & Lifestyle Advise

Arthritis:

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help reduce inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Psoriasis:

  • Include foods such as cherries, berries, leafy vegetables, salmon, sardines, and fish rich in omega-3 fatty acids.
  • Consume antioxidant-rich spices and herbs like cumin, ginger, sage and thyme.
  • Avoid processed foods, refined sugars, and fatty foods.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Cancer:

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Arthrate 7.5 Tablet 4's Substitute

Substitutes safety advice
  • Folitrax-7.5 Tablet 10's

    by Others

    14.67per tablet
  • Oncotrex 7.5 Tablet 10's

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    13.32per tablet
  • Mexate 7.5 mg Tablet 10's

    by Others

    13.37per tablet
  • Dermotrex 7.5 Tablet 10's

    by Others

    11.43per tablet
  • Mext 7.5 Tablet 10's

    by Others

    14.34per tablet
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