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Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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ORAL

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Not Returnable

About Asthadox M 400mg/10mg Tablet SR

Asthadox M 400mg/10mg Tablet SR is a respiratory medication, primarily used to treat and prevent asthma and chronic obstructive pulmonary diseases (COPD). Asthma is a breathing problem in which airways narrow, swell and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases that mainly include emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes).

Asthadox M 400mg/10mg Tablet SR is a combination of two medicines: Doxofylline (bronchodilator) and Montelukast (leukotriene receptor antagonist). Doxofylline works by relaxing muscles and widening the airways of the lungs. It treats the airflow obstruction in the lungs, thereby relieving chest tightness, wheezing and cough to make breathing easier. Montelukast blocks the leukotrienes (chemicals released in response when a body comes in contact with an allergen), thereby reducing inflammation and swelling in the nose. It also inhibits bronchoconstriction (narrowing of airways in the lungs that lead to breathing difficulties).

Your doctor will advise the dose and duration of the course based on the severity of your disease. The common side effects of Asthadox M 400mg/10mg Tablet SR include fever, nausea, vomiting, stomach pain/epigastric pain, headache, insomnia (difficulty in sleeping), irritation, sore throat, increased heart rate and flu-like symptoms. Most of these side effects of Asthadox M 400mg/10mg Tablet SR do not require any medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

Asthadox M 400mg/10mg Tablet SR is not intended for use during an acute asthma attack. Your doctor may suggest other medications for your sudden asthma attack. Please inform your doctor in advance if you have heart, liver, kidney and lung diseases, seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, stomach ulcers and viral infections before taking Asthadox M 400mg/10mg Tablet SR. It is advisable to check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines before starting Asthadox M 400mg/10mg Tablet SR.

Uses of Asthadox M 400mg/10mg Tablet SR

Chronic Obstructive Pulmonary Disease (COPD), Bronchitis, Asthma, Emphysema, Bronchospasm and Allergic rhinitis.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Asthadox M 400mg/10mg Tablet SR is a combination of Doxofylline and Montelukast. Doxofylline works by relaxing muscles and widening the airways of the lungs. It treats the airflow obstruction in the lungs, thereby relieving chest tightness, wheezing and cough to make breathing easier. Montelukast blocks leukotrienes (chemicals released in response when a body comes in contact with an allergen) and reduces inflammation and swelling in the nose. It also inhibits bronchoconstriction (narrowing of airways in the lungs that lead to breathing difficulties). Montelukast is also used to relieve exercise-induced bronchospasm (shortness of breath that occurs only during exercise).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not stop taking this medicine of your own unless advised by your doctor. Before taking Asthadox M 400mg/10mg Tablet SR, let your doctor know if have heart, liver, kidney and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, stomach ulcers and viral infections. Asthadox M 400mg/10mg Tablet SR is not intended for use during an acute asthma attack. Therapy with medicines like Montelukast should be cautiously administered in patients with neuropsychiatric disorders. Please seek medical advice if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines before starting Asthadox M 400mg/10mg Tablet SR.

Drug-Drug Interactions

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MontelukastRifapentine
Severe

Drug-Drug Interactions

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MontelukastRifapentine
Severe
How does the drug interact with Asthadox M 400mg/10mg Tablet SR:
Coadministration of Rifapentine with Asthadox M 400mg/10mg Tablet SR may reduce the blood levels and effects of Asthadox M 400mg/10mg Tablet SR. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Rifapentine with Asthadox M 400mg/10mg Tablet SR together can possibly result in an interaction, it can be taken if your doctor has advised it. If you experience increased side effects such as headache, fever, sore throat, cough, abdominal pain, diarrhea, earaches, runny nose, or behavior and mood changes consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Asthadox M 400mg/10mg Tablet SR:
Coadministration of Asthadox M 400mg/10mg Tablet SR and rifabutin can reduce the levels and effects of Rifabutin. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Asthadox M 400mg/10mg Tablet SR and rifabutin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience increased side effects such as headache, fever, sore throat, cough, abdominal pain, diarrhea, earache, runny nose, or behavior and mood changes consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Asthadox M 400mg/10mg Tablet SR:
Coadministration of Asthadox M 400mg/10mg Tablet SR and Phenytoin may reduce the blood levels and effects of Asthadox M 400mg/10mg Tablet SR. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Asthadox M 400mg/10mg Tablet SR and Phenytoin may interact with one another, but they can be taken together if your doctor has prescribed them. However, if you experience signs such as headache, fever, sore throat, cough, abdominal pain, diarrhoea, earache, runny nose, or behaviour and mood changes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Asthadox M 400mg/10mg Tablet SR:
Coadministration of Miconazole with Asthadox M 400mg/10mg Tablet SR may increase the blood levels and effects of Asthadox M 400mg/10mg Tablet SR. This increases the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between miconazole and Asthadox M 400mg/10mg Tablet SR, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, sore throat, cough, stomach pain, diarrhea, earache, runny nose, or uncommon, depression, confusion, difficulty concentrating, anxiety, hallucinations, irritability. memory impairment, restlessness, sleep walking, Consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with Asthadox M 400mg/10mg Tablet SR:
Coadministration of Asthadox M 400mg/10mg Tablet SR and primidone can reduce the levels and effects of Asthadox M 400mg/10mg Tablet SR.

How to manage the interaction:
Taking Asthadox M 400mg/10mg Tablet SR and Primidone together can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation, and swelling in nasal passages.
  • Eat foods rich in potassium, such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroot, as potassium is important for lung function and potassium deficiency may cause breathing problems.
  • Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to get relief from runny nose, cough, and sneezing.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress.
  • Quit smoking as it may reduce the effectiveness of the Asthadox M 400mg/10mg Tablet SR and irritate the lungs worsening breathing problems.
  • It is advised to avoid contact with known allergens (allergy-causing agents), such as pollen, dust, etc. Also, certain food items are known to cause allergies to you.
  • Maintain personal hygiene and keep your surroundings clean. 

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Asthadox M 400mg/10mg Tablet SR consists of Doxofylline and Montelukast. Doxofylline is a bronchodilator that works by relaxing muscles and widening the airways of the lungs. Montelukast is a leukotriene receptor antagonist that blocks leukotrienes (chemicals released in response when a body comes in contact with an allergen) and reduces inflammation and swelling in the nose.

Please take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Asthadox M 400mg/10mg Tablet SR is not recommended for use during a sudden asthma attack since it does not act right away. It is advised to please consult your doctor to prescribe a fast-acting inhaler for rescuing your sudden breathing problems.

Therapy with leukotriene receptor antagonists like Montelukast may worsen the symptoms of psychotic events in patients with a history of mental illness. Careful administration and monitoring are essential before taking Asthadox M 400mg/10mg Tablet SR in patients with neuropsychiatric disorders. Please consult your doctor before taking Asthadox M 400mg/10mg Tablet SR if you have been diagnosed or have a history of mental illness like depression, seizures (fits) etc.

It is essential to let your doctor know if you have any history of heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, hypoxaemia (low levels of oxygen in the blood), stomach ulcers and viral infections before taking Asthadox M 400mg/10mg Tablet SR.

Drug-Drug Interactions Checker List

  • ALLOPURINOL
  • CIMETIDINE
  • ERYTHROMYCIN
  • PHENYTOIN
  • SALBUTAMOL
  • CLINDAMYCIN

Special Advise

 

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times in a week and up to 4 nights in a month whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises, and self-care. 

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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