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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

ACETAZOLAMIDE-250MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIGLAUCOMA AGENTS

Country of origin

India
Other Info - AV71886

Author Details

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FAQs

Avva 250mg Tablet SR inhibits carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowering intraocular pressure and helping treat glaucoma.

Avva 250mg Tablet SR is used as an adjunct in the treatment of epilepsy. It inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat seizures.

Avva 250mg Tablet SR promotes diuresis of abnormal fluid retention due to congestive heart failure. Fluid retention or oedema is the accumulation of fluid in the body tissues.

Avva 250mg Tablet SR helps reduce the severity and duration of symptoms of altitude/mountain sickness, such as headache, stomach upset, dizziness, drowsiness, fatigue, and shortness of breath.

To treat your condition effectually, continue taking Avva 250mg Tablet SR for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Avva 250mg Tablet SR.

Avva 250mg Tablet SR might make your skin sensitive to sunlight. Avoid unnecessary and prolonged exposure to sunlight or tanning beds. Wear protective clothing, sunscreen and sunglasses whilst going out.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid or limit alcohol consumption as it might lead to increased drowsiness.

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Pregnancy

Unsafe

Avva 250mg Tablet SR belongs to pregnancy category C. Avoid using Avva 250mg Tablet SR if you are pregnant, think you are pregnant or planning for pregnancy. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide if Avva 250mg Tablet SR can be taken by breastfeeding mothers or not.

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Driving

Caution

Avva 250mg Tablet SR might cause dizziness and drowsiness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Avoid taking Avva 250mg Tablet SR if you have severe liver problems. Please consult your doctor if you have any concerns regarding the usage of Avva 250mg Tablet SR in patients with liver impairment.

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Kidney

Caution

Dose adjustment may be needed. Avoid taking Avva 250mg Tablet SR if you have/had severe kidney problems. Please consult your doctor if you have any concerns regarding the usage of Avva 250mg Tablet SR in patients with kidney impairment.

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Children

Unsafe

Avva 250mg Tablet SR is not recommended for children as safety and effectiveness have not been established.

About Avva 250mg Tablet SR

Avva 250mg Tablet SR belongs to a group of medicines called carbonic anhydrase inhibitors used to treat glaucoma, oedema (fluid retention), epilepsy, and to treat and prevent altitude/mountain sickness. Glaucoma is an eye condition that causes damage to the optic nerve due to abnormally increased pressure in the eye. Epilepsy is a disorder of the nervous system due to disturbed nerve cell activity in the brain. Fluid retention is a condition in which fluids are accumulated in the body tissues.
 
Avva 250mg Tablet SR contains ‘acetazolamide’, which inhibits carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowers intraocular pressure. Avva 250mg Tablet SR inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat certain dysfunctions of the central nervous system such as epilepsy. Avva 250mg Tablet SR reduces the activity of carbonic anhydrase, thereby helps lower fluid retention.
 
You are advised to take Avva 250mg Tablet SR for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, headache, and increased urination. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Avoid taking Avva 250mg Tablet SR if you are pregnant, think you are pregnant or planning for pregnancy. Consult your doctor if you are breastfeeding. Avva 250mg Tablet SR is not recommended for children as safety and effectiveness have not been established. Avva 250mg Tablet SR might cause dizziness and drowsiness; so, drive only if you are alert. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Avva 250mg Tablet SR

Glaucoma, Fluid retention/oedema, Epilepsy/seizures, Mountain sickness.

Medicinal Benefits Mweb

Medicinal Benefits

Avva 250mg Tablet SR belongs to a group of medicines called carbonic anhydrase inhibitors used to treat glaucoma, oedema (fluid retention), epilepsy, and to treat and prevent altitude/mountain sickness. Avva 250mg Tablet SR works by inhibiting the carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowering intraocular pressure. Avva 250mg Tablet SR inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat certain dysfunctions of the central nervous system, such as epilepsy. Avva 250mg Tablet SR reduces the activity of carbonic anhydrase, thereby helping lower fluid retention. Avva 250mg Tablet SR may also be used to treat muscle weakness/periodic paralysis and to lower the increased pressure in the areas surrounding the spinal cord and brain.

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Side Effects of Avva 250mg Tablet SR

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Increased urination
  • Loss of appetite
  • Dizziness

Drug Warnings

Do not take Avva 250mg Tablet SR if you are allergic to any of its contents; if you have severe kidney/liver problems, chronic non-congestive angle-closure glaucoma, Addison’s disease, if you have low sodium and/or potassium levels or high chlorine levels. Inform your doctor if you have lung problems, kidney stones, electrolyte imbalance, adrenal gland problems, diabetes, or heart problems. Avoid taking Avva 250mg Tablet SR if you are pregnant, think you are pregnant or planning for pregnancy. Consult your doctor if you are breastfeeding. Avva 250mg Tablet SR is not recommended for children as safety and effectiveness have not been established. Avva 250mg Tablet SR might cause dizziness and drowsiness; so, drive only if you are alert. Avva 250mg Tablet SR might make your skin sensitive to sunlight; therefore, wear protective clothing and sunscreen whilst going out.

Drug-Drug Interactions

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AcetazolamideCisapride
Critical
AcetazolamideZiprasidone
Severe

Drug-Drug Interactions

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AcetazolamideCisapride
Critical
How does the drug interact with Avva 250mg Tablet SR:
Co-administration of Cisapride with Avva 250mg Tablet SR can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Avva 250mg Tablet SR with Cisapride lead to an interaction, please consult a doctor before taking it. Consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not discontinue the medications without consulting a doctor.
AcetazolamideZiprasidone
Severe
How does the drug interact with Avva 250mg Tablet SR:
Co-administration of Avva 250mg Tablet SR with Ziprasidone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Avva 250mg Tablet SR and Ziprasidone, they can be taken together if prescribed by a doctor. If you develop sudden dizziness, lightheadedness, fainting, contact a doctor immediately. Do not discontinue any medication without talking to a doctor.
AcetazolamideSalsalate
Severe
How does the drug interact with Avva 250mg Tablet SR:
Co-administration of Avva 250mg Tablet SR together with Salsalate can cause ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, rapid breathing, fever, seizure (convulsions).

How to manage the interaction:
There may be a possibility of interaction between Avva 250mg Tablet SR and Salsalate, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like ringing in your ears, headache, feeling sick, throwing up, feeling dizzy, feeling confused, breathing fast, having a fever, or having a seizure, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AcetazolamideDroperidol
Severe
How does the drug interact with Avva 250mg Tablet SR:
Co-administration of Droperidol can enhance the effects of Avva 250mg Tablet SR can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Avva 250mg Tablet SR and Droperidol, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: dizziness or lightheadedness, fainting, difficulty breathing, heart palpitations, weakness, feeling sleepy or confused, muscle pain, or feeling nauseous or vomiting. Do not stop using any medications without talking to a doctor.
AcetazolamideZonisamide
Severe
How does the drug interact with Avva 250mg Tablet SR:
Co-administration of Avva 250mg Tablet SR with Zonisamide may increase the risk or severity of metabolic acidosis (elevated levels of acid in the blood) and kidney stones.

How to manage the interaction:
Although there is a possible interaction between Avva 250mg Tablet SR and Zonisamide, you can take these medicines together if prescribed by your doctor. If you experience symptoms such as fever, sudden back pain, abdominal pain, blood in the urine, tiredness, loss of appetite, irregular heartbeat, decreased sweating, trouble thinking clearly, and rapid breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcetazolamideDronedarone
Severe
How does the drug interact with Avva 250mg Tablet SR:
Co-administration of Avva 250mg Tablet SR with Dronedarone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Avva 250mg Tablet SR and Dronedarone, you can take these medicines together if prescribed by a doctor. If you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with Dronedarone, contact a doctor immediately. Also, inform your doctor if you experience signs of electrolyte disturbance such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not discontinue the medication without consulting a doctor.
AcetazolamideMethenamine
Severe
How does the drug interact with Avva 250mg Tablet SR:
Co-administration of Avva 250mg Tablet SR may reduce the effectiveness of Methenamine.

How to manage the interaction:
Although there is a possible interaction between Avva 250mg Tablet SR and Methenamine, you can take these medicines together if prescribed by a doctor. However, frequent urine pH testing may be recommended. Do not discontinue the medication without consulting a doctor.
AcetazolamideDofetilide
Severe
How does the drug interact with Avva 250mg Tablet SR:
Co-administration of Avva 250mg Tablet SR with Dofetilide may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Avva 250mg Tablet SR and Dofetilide, you can take these medicines together if prescribed by a doctor. If you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with dofetilide, contact a doctor immediately. Also, inform a doctor if you experience signs of electrolyte disturbance such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not discontinue the medication without consulting a doctor.
AcetazolamideMetformin
Severe
How does the drug interact with Avva 250mg Tablet SR:
Co-administration of Metformin with Avva 250mg Tablet SR may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Metformin with Avva 250mg Tablet SR, you can take these medicines together if prescribed by a doctor. However, if you have symptoms such as weakness, muscle pain, chest pain contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcetazolamideAspirin
Severe
How does the drug interact with Avva 250mg Tablet SR:
Coadministration of Aspirin with Avva 250mg Tablet SR may cause side effects.

How to manage the interaction:
Although there is a possible interaction between aspirin and Avva 250mg Tablet SR, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, or rapid breathing, fever, and seizure, please contact a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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ACETAZOLAMIDE-250MGOther aplastic anaemias
Severe
ACETAZOLAMIDE-250MGOther disorders of adrenal gland
Severe

Drug-Diseases Interactions

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ACETAZOLAMIDE-250MGOther aplastic anaemias
Severe
How does the disease interact with Avva 250mg Tablet SR:
The use of carbonic anhydrase inhibitors may rarely cause bone marrow suppression and blood dyscrasias at recommended dosages.

How to manage the interaction:
Avva 250mg Tablet SR should be used with caution in patients with aplastic anemia ( body stops producing enough new blood cells), thrombocytopenia (low number of platelets in the blood) or thrombocytopenia purpura (low levels of platelets that prevent bleeding), leukopenia (low white blood cells in blood), agranulocytosis (extremely low levels of white blood cells), and hemolytic anemia (red blood cells are destroyed faster than they can be replaced). A baseline CBC and platelet count is recommended, as well as monitoring at regular intervals during therapy.
ACETAZOLAMIDE-250MGOther disorders of adrenal gland
Severe
How does the disease interact with Avva 250mg Tablet SR:
The use of carbonic anhydrase inhibitors is contraindicated in patients with adrenal insufficiency.

How to manage the interaction:
It should be used with extreme caution in patients with adrenal insufficency (adrenal glands don't make enough hormone, cortisol) and monitoring of electrolyte levels is recommended.
ACETAZOLAMIDE-250MGGlaucoma
Severe
How does the disease interact with Avva 250mg Tablet SR:
The use of carbonic anhydrase inhibitors is contraindicated in patients with closed-angle glaucoma.

How to manage the interaction:
It should be used with extreme caution in glaucoma patients.
ACETAZOLAMIDE-250MGOther disorders of fluid, electrolyte and acid-base balance
Severe
How does the disease interact with Avva 250mg Tablet SR:
The use of carbonic anhydrase inhibitors is contraindicated in patients with hypokalemia .

How to manage the interaction:
If you have symptoms such as constipation, extreme tiredness, muscle damage, tingling or numbness, contact your doctor immediately.
ACETAZOLAMIDE-250MGOther disorders of fluid, electrolyte and acid-base balance
Severe
How does the disease interact with Avva 250mg Tablet SR:
The use of carbonic anhydrase inhibitors is contraindicated in patients with hyponatremia .

How to manage the interaction:
If you have symptoms such as headache, confusion, nausea, vomiting, muscle weakness or cramps, extreme tiredness or restlessness, contact your doctor immediately.
ACETAZOLAMIDE-250MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Avva 250mg Tablet SR:
The use of some carbonic anhydrase inhibitors is contraindicated in patients with severe kidney disease.

How to manage the interaction:
If you have symptoms such as pain, difficulty or discomfort while urinating, bad-smelling urine, cloudy or foamy urine, low back pain on one side, loss of appetite , flank pain between ribs and hips and fever not caused by an infection and that does not go away, contact your doctor immediately.
ACETAZOLAMIDE-250MGAlcoholic liver disease
Severe
How does the disease interact with Avva 250mg Tablet SR:
The use of carbonic anhydrase inhibitors is contraindicated in patients with marked liver disease or cirrhosis.

How to manage the interaction:
It should be used with extreme caution in patients with mild to moderate liver disease, as clearance of the drug may be decreased. A dose reduction might be needed, and monitoring of the liver function is recommended.
ACETAZOLAMIDE-250MGOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Avva 250mg Tablet SR:
carbonic anhydrase inhibitors should be administered cautiously in patients with respiratory acidosis

How to manage the interaction:
It should be used with caution in patients with respiratory acidosis and in conditions such as emphysema (lung disease that causes shortness of breath), pulmonary obstruction, etc. Respiratory status should be monitored during therapy.
ACETAZOLAMIDE-250MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Avva 250mg Tablet SR:
Carbonic anhydrase inhibitor anticonvulsants should be administered cautiously in patients with reduced renal dysfunction.

How to manage the interaction:
It should be used with caution in patients with reduced kidney function and a dose adjustment may be required based on the level of impairment.
ACETAZOLAMIDE-250MGType 1 diabetes mellitus
Moderate
How does the disease interact with Avva 250mg Tablet SR:
carbonic anhydrase inhibitors should be administered cautiously in patients with diabetes mellitus.

How to manage the interaction:
It should be used with caution in diabetic patients, and regular monitoring of blood glucose levels is recommended during therapy.
ACETAZOLAMIDE-250MGGout
Moderate
How does the disease interact with Avva 250mg Tablet SR:
carbonic anhydrase inhibitors should be administered cautiously in patients with gout.

How to manage the interaction:
It should be used with caution in patients with gout and monitoring of uric acid levels is recommended.
ACETAZOLAMIDE-250MGDisorders resulting from impaired renal tubular function
Moderate
How does the disease interact with Avva 250mg Tablet SR:
carbonic anhydrase inhibitors should be administered cautiously in patients with metabolic or hyperchloremic acidosis

How to manage the interaction:
Avva 250mg Tablet SR should be used with caution in patients with metabolic or hyperchloremic acidosis or with conditions that lead to acidosis (renal disease, severe respiratory disorders, diarrhea).

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • METFORMIN
  • GLICLAZIDE
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • TOPIRAMATE
  • PREDNISOLONE
  • DORZOLAMIDE
  • BRINZOLAMIDE
  • QUINIDINE
  • LITHIUM
  • CICLOSPORIN
  • SODIUM BICARBONATE

Habit Forming

No

Special Advise

  • If you are due to have any surgery, inform the doctor/surgeon that you are taking Avva 250mg Tablet SR.
  • Your doctor may advise frequent blood tests whilst taking Avva 250mg Tablet SR.
  • Regular monitoring of serum electrolyte levels is advised.
  • Talk to your doctor immediately if you have thoughts of harming or killing yourself.

Diet & Lifestyle Advise

GLAUCOMA:

  • Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.
  • Limit coffee intake as it may increase pressure in the eye. Replace coffee with green tea.
  • Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

EPILEPSY:

  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan to help those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

FLUID RETENTION:

  • Limit salt intake.
  • Consume foods rich in magnesium, such as nuts, dark chocolate, whole grains, and leafy vegetables.
  • Include foods rich in vitamin B6, such as potatoes, bananas, meat, and walnuts.
  • Potassium reduces water retention, therefore, include potassium-rich foods such as avocados, tomatoes, and bananas.
  • Avoid refined carbohydrates.
  • Walking can help reduce fluid retention.

Avva 250mg Tablet SR Substitute

Substitutes safety advice
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