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Prescription drug
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Composition :

ARIPIPRAZOLE-15MG

Manufacturer/Marketer :

Cnx Health Care Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable
Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
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Therapeutic Class

[ANTIPSYCHOTICS]

Country of origin

India

Manufacturer/Marketer address

1 A, PATANWALA INDUSTRTIAL COMPOUND, LBS ROAD, NEAR SHREYAS CINEMA, GHATKOPAR-W, MUMBAI-400 086
Other Info - AXE0231

Author Details

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FAQs

Axepine 15 mg Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and prevents its overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbelief and unfriendliness) of schizophrenia. Also, Axepine 15 mg Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Thereby, Axepine 15 mg Tablet improves behaviour, thoughts and helps in having a better social life and enables to comfortably do daily activities.

No, you are not recommended to take Axepine 15 mg Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Axepine 15 mg Tablet in the blood leading to increased adverse effects. However, please consult a doctor before taking Axepine 15 mg Tablet with other medicines.

Axepine 15 mg Tablet may cause weight gain in some patients but it is not necessary for everyone taking Axepine 15 mg Tablet to experience this side effect. However, in order to avoid gaining weight while taking Axepine 15 mg Tablet , you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.

Axepine 15 mg Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Axepine 15 mg Tablet .

Yes, Axepine 15 mg Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Axepine 15 mg Tablet and inform your doctor if you have diabetes before taking Axepine 15 mg Tablet . However, if you experience dry mouth, increased thirst or urination, fruity breath odour, please consult a doctor as these might be signs of high blood sugar.

No, you are not recommended to stop taking Axepine 15 mg Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Axepine 15 mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Axepine 15 mg Tablet , please consult your doctor so that the dose may be gradually reduced.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

You are recommended to avoid alcohol consumption with Axepine 15 mg Tablet as it may increase the risk of side effects such as dizziness, drowsiness or difficulty in concentrating.

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Pregnancy

Consult your doctor

Axepine 15 mg Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy, especially in the third trimester as it may cause adverse effects in the newborn baby. Axepine 15 mg Tablet may cause extrapyramidal and/or withdrawal symptoms in newborn babies with third-trimester exposure.

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Breast Feeding

Consult your doctor

Avoid breastfeeding while taking Axepine 15 mg Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Safe if prescribed

Axepine 15 mg Tablet may cause dizziness or vision problems such as blurred vision. Therefore, avoid driving if you feel dizzy or have vision disturbances after taking Axepine 15 mg Tablet .

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Liver

Consult your doctor

Take Axepine 15 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Take Axepine 15 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Safe if prescribed

Axepine 15 mg Tablet is not recommended for children below 15 years due to the increased risk of adverse effects. However, please consult a doctor before giving Axepine 15 mg Tablet to children.

About Axepine 15 mg Tablet

Axepine 15 mg Tablet belongs to a class of drugs called antipsychotics and mood stabilizers primarily used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Axepine 15 mg Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterized by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused due to disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Axepine 15 mg Tablet contains Aripiprazole which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing its overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. Axepine 15 mg Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Axepine 15 mg Tablet improves mood swings, depression, and other psychotic problems. 

Take Axepine 15 mg Tablet as prescribed. Your doctor will advise you how often you take Axepine 15 mg Tablet based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Axepine 15 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Axepine 15 mg Tablet or any other medicines, please tell your doctor. Axepine 15 mg Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions such as dizziness, inability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Axepine 15 mg Tablet if you are pregnant or breastfeeding and consult a doctor. Axepine 15 mg Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Axepine 15 mg Tablet , please contact a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Axepine 15 mg Tablet . 

Uses of Axepine 15 mg Tablet

Schizophrenia, Mania, Bipolar disorder

Medicinal Benefits Mweb

Key Benefits

Axepine 15 mg Tablet contains Aripiprazole which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Axepine 15 mg Tablet inhibits the dopamine receptor in our brain thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Axepine 15 mg Tablet improves overall behavior and thoughts and helps in having a better social life and comfortably doing daily activities. Axepine 15 mg Tablet may be used in combination with other medicines to treat depression. Additionally, Axepine 15 mg Tablet is also used to reduce unwanted sounds (tics) severity in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements). 

Directions for Use

Tablet: Take it with or without food as advised by the doctor and swallow it as a whole with a glass of water. Do not crush, chew or break it. Oral solution: Shake the bottle well before use and take it as advised by the doctor. Take it with the help of a measuring cup that is provided with the pack.

Side Effects of Axepine 15 mg Tablet

  • Drowsiness
  • Headache
  • Tiredness
  • Akathisia (inability to sit still)
  • Difficulty in sleeping
  • Light-headedness
  • Indigestion
  • Shaking
  • Blurred vision
  • Nausea
  • Vomiting
  • Anxiety
  • Increased saliva production

Drug Warnings

If you are allergic to Axepine 15 mg Tablet or any other medicines, please tell your doctor. Axepine 15 mg Tablet should be used with caution in elderly patients above 65 years of age as there is an increased risk of adverse reactions such as dizziness, changes in the ability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Axepine 15 mg Tablet if you are pregnant or breastfeeding and consult a doctor. Axepine 15 mg Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Axepine 15 mg Tablet , please contact a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or are advised to stop taking Axepine 15 mg Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Axepine 15 mg Tablet .

Drug-Drug Interactions

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AripiprazoleEnzalutamide
Severe

Drug-Drug Interactions

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How does the drug interact with Axepine 15 mg Tablet:
Co-administration of Metoclopramide with Axepine 15 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Axepine 15 mg Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AripiprazoleEnzalutamide
Severe
How does the drug interact with Axepine 15 mg Tablet:
When Axepine 15 mg Tablet is taken with Enzalutamide, the amount of Axepine 15 mg Tablet in the blood may decrease. This might reduce Axepine 15 mg Tablet's ability to effectively treat disease.

How to manage the interaction:
Although there is a possible interaction between Enzalutamide and Axepine 15 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
AripiprazoleOxycodone
Severe
How does the drug interact with Axepine 15 mg Tablet:
Using Axepine 15 mg Tablet together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine 15 mg Tablet with Oxycodone together can result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazoleDezocine
Severe
How does the drug interact with Axepine 15 mg Tablet:
Using Axepine 15 mg Tablet together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine 15 mg Tablet with Dezocine together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Axepine 15 mg Tablet:
Combining Axepine 15 mg Tablet with Mirabegron can increase the levels of Axepine 15 mg Tablet in the body. This can lead to increased risk or severity of side effects.

How to manage the interaction:
Although taking Mirabegron and Axepine 15 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs like feeling sleepy, having seizures, unusual muscle movements, low blood pressure, feeling confused, muscle spasms, twitching in your jaw, shaking or jerking in your arms and legs, feeling nervous or restless, dizziness, lightheaded, or fainting contact the doctor right away. Do not stop using any medications without a doctor's advice.
AripiprazoleMethadone
Severe
How does the drug interact with Axepine 15 mg Tablet:
Using Axepine 15 mg Tablet together with Methadone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Axepine 15 mg Tablet with Methadone together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
How does the drug interact with Axepine 15 mg Tablet:
Using Axepine 15 mg Tablet together with Pentazocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Axepine 15 mg Tablet and Pentazocine together can cause an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Axepine 15 mg Tablet:
Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Axepine 15 mg Tablet.

How to manage the interaction:
Co-administration of Axepine 15 mg Tablet with Topiramate can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, consult the doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced sweating or a fever. Do not discontinue any medications without consulting a doctor.
AripiprazoleHydrocodone
Severe
How does the drug interact with Axepine 15 mg Tablet:
Using Axepine 15 mg Tablet together with Hydrocodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Axepine 15 mg Tablet and Hydrocodone together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like trouble breathing, feeling very sleepy, or having trouble focusing, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Axepine 15 mg Tablet:
Taking carbamazepine and Axepine 15 mg Tablet together can reduce the effects of Axepine 15 mg Tablet which may make the medication less effective.

How to manage the interaction:
Taking carbamazepine and Axepine 15 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • METOPROLOL
  • OLANZAPINE
  • FLUOXETINE
  • PAROXETINE
  • VENLAFAXINE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • AMIODARONE
  • FLECAINIDE
  • QUINIDINE
  • NEVIRAPINE
  • EFAVIRENZ
  • INDINAVIR
  • RITONAVIR
  • IBUPROFEN
  • RIFAMPICIN
  • RIFABUTIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Habit Forming

No

Special Advise

  • Elderly patients more than 65 years with dementia-related psychosis treated with Axepine 15 mg Tablet can be at an increased risk of death. 
  • Axepine 15 mg Tablet is not prescribed and approved for the treatment of dementia-related psychosis. 
  • Increased risk of suicidal thinking and behavior changes has been observed in children, adolescents, and young adults taking Axepine 15 mg Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.  

Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Axepine 15 mg Tablet .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.
  • Cut down sugars, salt and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Do regular exercise and maintain a stable weight as Axepine 15 mg Tablet may cause weight gain.
  • Avoid consumption of alcohol as it may increase drowsiness.

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