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Written By ,
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

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Whats That

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Composition :

BARICITINIB-1MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

IMMUNOMODULATORS

Country of origin

INDIA

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - BAR0197

FAQs

Barinat 1 Tablet works by preventing the virus from attaching to the body’s cell receptors and thereby blocking its entry and spread.

If you suffer from Chronic Kidney Disease, please consult with your doctor before using Barinat 1 Tablet and discuss any concerns with them. Barinat 1 Tablet is to be used with caution in those suffering from kidney and liver problems.

Not enough literature exists to ascertain the effects of Barinat 1 Tablet on fertility. However, Barinat 1 Tablet should be absolutely avoided in pregnancy. Please consult your doctor in case of any concerns.

Advanced age, obesity, chronic kidney disease, lung disease, sickle cell disease, neurodevelopmental disorders (for example cerebral palsy) and diseases of metabolism are some risk factors for disease progression.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not recommended to use alcohol with Barinat 1 Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Barinat 1 Tablet is absolutely contraindicated during pregnancy.

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Breast Feeding

Caution

Not enough studies exist to ascertain the effect of Barinat 1 Tablet on nursing. Barinat 1 Tablet is not recommended to use without contraception during and for at least 1 week after treatment. Please consult your doctor in case of any concerns.

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Driving

Safe if prescribed

Barinat 1 Tablet does not affect your ability to drive.

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Liver

Caution

Exercise caution before using Barinat 1 Tablet in case of established liver disease as it may cause a derangement of liver enzymes. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Barinat 1 Tablet in case of established kidney disease. Please consult your doctor to address any concerns.

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Children

Caution

Not enough studies exist to ascertain the effect of Barinat 1 Tablet in children. Please consult your doctor in case of any concerns.

About Barinat 1 Tablet

Barinat 1 Tablet belongs to the group of immunomodulators. Barinat 1 Tablet is used in the treatment of hospitalised cases of coronavirus disease, an infection caused by COVID-19 and is also used to treat Rheumatoid Arthritis. Rheumatoid arthritis is a chronic inflammatory and autoimmune disorder of the joints. Atopic dermatitis is a skin disease in which the skin becomes red, inflamed and itchy.  Coronavirus disease is an infectious disease caused by SARS-CoV-2. It can range from a mild cold to a serious form of pneumonia

Barinat 1 Tablet contains ‘’Baricitinib.’’ Barinat 1 Tablet works by inhibiting viral entry into body cells, limits viral replication and also controls the release of inflammatory mediators called cytokines.

Take Barinat 1 Tablet as prescribed by the doctor. Barinat 1 Tablet may cause certain common side effects such as throat infection, fatigue and high blood cholesterol. Most of these adverse effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to Barinat 1 Tablet or any of its components. Keep your doctor informed if you suffer from any medical disorders. Avoid Barinat 1 Tablet in case of a history of thromboembolism, abdominal disorders such as diverticulitis, cancer, liver disease, chronic infections such as tuberculosis, hepatitis B and C and shingles, and any anaemias. Keep your doctor informed if you have recently had any surgery or are scheduled for surgery in the near future. Offer a detailed medical and vaccination history. Discuss any recent vaccinations with the doctor. Inform the doctor if you are on any other JAK-2 inhibitor medicines, painkillers, steroids and/or drugs that affect the immunity and immune system of the body. Consult your doctor if you are planning to get pregnant or are breastfeeding. Avoid Barinat 1 Tablet use with alcohol.

Uses of Barinat 1 Tablet

Rheumatoid Arthritis, Atopic Dermatitis, COVID-19

Medicinal Benefits Mweb

Medicinal Benefits

Barinat 1 Tablet is an immunomodulator used in the treatment of various types of cancers and infections such as Covid-19. Barinat 1 Tablet contains Baricitinib. Baricitinib works by inhibiting the entry of the virus into the body cells. Barinat 1 Tablet targets an enzyme called Janus kinase (JAK-2), which is responsible for the formation of cytokines. Cytokines are inflammatory mediators. Hence, by inhibiting a cytokine-forming enzyme, Baricitinib reduces the level of cytokines in the body, thus relieving signs of inflammation.  In addition, Baricitinib works by reducing viral replication, thus arresting the progress of the disease.

Directions for Use

Take Barinat 1 Tablet with or without food as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Barinat 1 Tablet

  • Throat infections
  • High blood cholesterol
  • Cold sores
  • Rash
  • Acne

Drug Warnings

It is advisable to inform the doctor if you are allergic to Barinat 1 Tablet or any of its components. Keep your doctor informed if you suffer from any medical disorders. Avoid Barinat 1 Tablet in case of a history of thromboembolism, abdominal disorders such as diverticulitis, cancer, liver disease, chronic infections such as tuberculosis, hepatitis B and C and shingles, and any anaemias. Keep your doctor informed if you have recently had any surgery or are scheduled for surgery in the near future. Offer a detailed medical and vaccination history. Discuss any recent vaccinations with the doctor. Inform the doctor if you are on any other JAK-2 inhibitor medicines, DMARD’s, painkillers, steroids and/or any drugs that affect the immunity and immune system of the body. Consult your doctor if you are planning to get pregnant or are breastfeeding. Avoid Barinat 1 Tablet use with alcohol.

Drug-Drug Interactions

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BaricitinibAlefacept
Severe

Drug-Drug Interactions

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How does the drug interact with Barinat 1 Tablet:
Co-administration of Barinat 1 Tablet with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Ciclosporin with Barinat 1 Tablet is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
BaricitinibAlefacept
Severe
How does the drug interact with Barinat 1 Tablet:
Coadministration of Barinat 1 Tablet and alefacept can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Barinat 1 Tablet can be taken with alefacept if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Barinat 1 Tablet:
Co-administration of Barinat 1 Tablet and Melphalan together can raise the risk of serious infections.

How to manage the interaction:
Although there is an interaction, Barinat 1 Tablet can be taken with Melphalan if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Barinat 1 Tablet:
Coadministration of Barinat 1 Tablet and osimertinib can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Barinat 1 Tablet can be taken with osimertinib if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
BaricitinibProcainamide
Severe
How does the drug interact with Barinat 1 Tablet:
Coadministration of Barinat 1 Tablet and procainamide can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Barinat 1 Tablet can be taken with procainamide if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Barinat 1 Tablet:
Coadministration of Barinat 1 Tablet and docetaxel can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Barinat 1 Tablet can be taken with docetaxel if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Barinat 1 Tablet:
Taking Barinat 1 Tablet and temozolomide can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Barinat 1 Tablet can be taken with temozolomide if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
BaricitinibAlemtuzumab
Severe
How does the drug interact with Barinat 1 Tablet:
Combining Alemtuzumab with Barinat 1 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Barinat 1 Tablet with Alemtuzumab can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Barinat 1 Tablet:
Using Barinat 1 Tablet together with budesonide may increase the risk of serious infections.

How to manage the interaction:
Taking budesonide along with Barinat 1 Tablet can lead to an interaction, it can be taken if recommended by a doctor. If you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in sputum, weight loss, red or irritated skin, body sores, and discomfort or burning while urinating, severe stomach pain, nausea, or vomiting, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Barinat 1 Tablet:
Using Barinat 1 Tablet together with Doxorubicin may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, Barinat 1 Tablet can be taken with doxorubicin if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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BARICITINIB-1MGHigh fat foods
Mild

Drug-Food Interactions

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BARICITINIB-1MGHigh fat foods
Mild
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Coadministration of Barinat 1 Tablet and high-fat meals can decrease the absorption of Barinat 1 Tablet. Avoid fatty food and oily food while being treated with Barinat 1 Tablet.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TRAMADOL
  • ABATACEPT
  • METHOTREXATE

Habit Forming

No

Special Advise

  • Discuss contraception with your doctor while taking Barinat 1 Tablet .
  • Use Barinat 1 Tablet with caution in the elderly as they’re more prone to infections.

Diet & Lifestyle Advise

  • Keep a healthy state of mind. Fear is the one of the biggest causes of decreased immunity. See a therapist if you feel the need. 
  • Meditation, music and yoga have also proven very effective in helping with mental health.
  • Keep yourself at a safe distance from people.
  • Always sneeze or cough into your elbow and keep a handkerchief on you.
  • Wash your hands with soap and water and keep yourself clean.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. Load up on Vitamin-C rich citrus fruit for enhanced immunity.
  • Do not forget to take your Vitamin B complex and Vitamin C supplements every day as these are essential for the body and immunity.
  • Steam inhalation for 3-5 minutes every day and salt-water gargle with warm water has been proven very effective in keeping respiratory infections at bay and in promoting health. 
  • Avoid taking Barinat 1 Tablet with alcohol as there may be an interaction.
  • Stay hydrated by drinking plenty of water as dehydration is often seen in pneumonia.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. Doing weight-bearing exercises can prove very helpful in promoting bone health.
  • Avoid tobacco use as smoking hampers lung health and makes breathing even more difficult.
  • Spend time under the sun (however with proper sunscreen) for quality intake of Vitamin D. Vitamin D is necessary for the absorption of Calcium, which is the most important component of bones and can help with bone and joint pain.

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