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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Synonym :

BENDAMUSTINE HYDROCHLORIDE

Composition :

BENDAMUSTINE-100MG

Manufacturer/Marketer :

GLS Pharma Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India
Other Info - BE77446

FAQs

Bendamax 100 Injection contains Bendamustine, which inhibits the DNA and RNA transcription essential for cancer cell growth.

Bendamax 100 Injection may cause reactivation of serious infections, myelosuppression, tumour lysis syndrome, and anaphylactic reactions in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.

Disclaimer

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Alcohol

Caution

Limit or avoid consumption of alcohol as it may worsen your condition.

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Pregnancy

Unsafe

Bendamax 100 Injection is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Bendamax 100 Injection. Use reliable methods of birth control while on treatment with Bendamax 100 Injection.

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Breast Feeding

Caution

If you are a nursing mother, inform your doctor before receiving Bendamax 100 Injection. You should not breastfeed while on treatment with Bendamax 100 Injection.

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Driving

Not applicable

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Bendamax 100 Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition. Bendamax 100 Injection is not recommended for use in patients with severe liver disease.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Bendamax 100 Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition. This medicine should be avoided for patients with CrCl <40 ml/min.

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Children

Unsafe

Bendamax 100 Injection is not recommended for use in children as the safety and efficacy is not established.

About Bendamax 100 Injection

Bendamax 100 Injection belongs to a class of anti-cancer medicines used in the treatment of Leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. This medicine is used in the treatment of Chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin’s leukemia (NHL) that has progressed during six months of treatment with rituximab or rituximab-containing treatment.

Bendamax 100 Injection contains Bendamustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.

Bendamax 100 Injection may cause certain side effects, such as nausea, vomiting, diarrhea, stomach pain, anorexia, decreased weight, constipation, fever, decreased platelet count, fatigue, cough, headache, rash, injection site reactions and pain at the site of injection. If the side effects bother you, inform your doctor. A trained healthcare professional will administer Bendamax 100 Injection. Hence, do not self-administer.

Bendamax 100 Injection should be avoided if you are allergic to it or any other components present in it. Before receiving this injection, inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiac disorders, cancer, active infections, skin problems, or any allergic conditions. Bendamax 100 Injection is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

Uses of Bendamax 100 Injection

Non-Hodgkin’s disease, Chronic Lymphocytic Leukaemia.

Medicinal Benefits Mweb

Medicinal Benefits

Bendamax 100 Injection contains Bendamustine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells. This medicine is used in the treatment of chronic lymphocytic leukemia and non-Hodgkin’s leukemia.

Directions for Use

A trained healthcare professional will administer Bendamax 100 Injection. Hence, do not self-administer. 

Side Effects of Bendamax 100 Injection

  • Diarrhoea
  • Back pain
  • Vomiting
  • Stomach pain
  • Cough
  • Bruising or bleeding gums
  • Pain at the site of injection
  • Fever
  • Anorexia
  • Constipation
  • Decreased platelet count
  • Rashes
  • Decreased weight
  • Injection site reactions

Drug Warnings

Bendamax 100 Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before receiving this injection, inform your doctor if you have any history of liver/kidney disease, cardiac disorders, cancer, active infections, skin problems, or any allergic conditions. Bendamax 100 Injection may cause myelosuppression, active infections, severe skin reactions, tumor lysis syndrome (tumor cells release their contents into the bloodstream), other malignancies, and hypersensitivity reactions in some patients. Hence, careful monitoring should be done during the entire treatment. Bendamax 100 Injection may cause embryo-fetal toxicity. Hence, if you are pregnant or planning to become pregnant, inform your doctor beforehand. Before nursing, a breastfeeding mother should ask her oncologist whether this medicine is safe for use or not. Bendamax 100 Injection is not recommended for use in children as the safety and efficacy are not established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Bendamax 100 Injection:
Combining Bendamax 100 Injection with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Bendamax 100 Injection and Baricitinib together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bendamax 100 Injection:
When Bendamax 100 Injection is taken with Infliximab, it can cause the metabolism of Bendamax 100 Injection to speed up. This can increase the risk of developing serious infections.

How to manage the interaction:
Taking Bendamax 100 Injection with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate, contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Bendamax 100 Injection:
Using tofacitinib together with Bendamax 100 Injection may increase the risk of developing serious infections.

How to manage the interaction:
Taking Tofacitinib with Bendamax 100 Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bendamax 100 Injection:
Combining Bendamax 100 Injection with Clozapine can increase the risk of neutropenia.

How to manage the interaction:
Although there is a possible interaction between Bendamax 100 Injection and Clozapine, you can take these medicines together if prescribed by your doctor. However, consult your doctor immediately If you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
How does the drug interact with Bendamax 100 Injection:
Combining Bendamax 100 Injection with Leflunomide can increase the likelihood of negative side effects.

How to manage the interaction:
There may be a possibility of interaction between Bendamax 100 Injection and Leflunomide, but it can be taken if prescribed by a doctor. If you have any of these symptoms - like an infection, complications, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bendamax 100 Injection:
Combining Cladribine with Bendamax 100 Injection can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Bendamax 100 Injection and Cladribine, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • CLOPIDOGREL
  • RITONAVIR
  • CLOZAPINE
  • CIMETIDINE
  • RIFAMPICIN
  • PHENYTOIN
  • ETANERCEPT
  • GOLIMUMAB
  • INFLIXIMAB
  • BARICITINIB

Habit Forming

No

Special Advise

  • A blood test should be performed, such as a liver function test, or renal function test, to check for liver/kidney function.
  • Weekly blood tests should be done during the treatment to check for CBC (Complete blood count).

Diet & Lifestyle Advise

  • After your treatment begins, dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Bendamax 100 Injection Substitute

Always consult your doctor before taking any new medications and supplements

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