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  3. Biobin 500 mg/5 ml Injection 5 ml

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

CYTARABINE-100MG/ML

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

D' Block, 3rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - BIO2208

FAQs

Biobin 500 mg/5 ml Injection 5 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Biobin 500 mg/5 ml Injection 5 ml as it may cause infections.

Biobin 500 mg/5 ml Injection 5 ml may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Biobin 500 mg/5 ml Injection 5 ml if you are planning to become pregnant.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol with Biobin 500 mg/5 ml Injection 5 ml as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Biobin 500 mg/5 ml Injection 5 ml. You should not become pregnant while on treatment with Biobin 500 mg/5 ml Injection 5 ml.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving Biobin 500 mg/5 ml Injection 5 ml. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Biobin 500 mg/5 ml Injection 5 ml causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Biobin 500 mg/5 ml Injection 5 ml.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Biobin 500 mg/5 ml Injection 5 ml. It may lead to CNS toxicity in high doses.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Biobin 500 mg/5 ml Injection 5 ml as it may lead to kidney failure. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Biobin 500 mg/5 ml Injection 5 ml, combined with other approved anti-cancer medications, is suggested for inducing remission in adults and children with acute non-lymphocytic leukemia. Consult your doctor for more information.

About Biobin 500 mg/5 ml Injection 5 ml

Biobin 500 mg/5 ml Injection 5 ml is an anticancer medicine used in the treatment of leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. Biobin 500 mg/5 ml Injection 5 ml is used in the treatment of different types of leukemias, such as acute non-lymphocytic leukemia, acute lymphocytic leukemia, chronic myelocytic leukemia and meningeal leukemia.

Biobin 500 mg/5 ml Injection 5 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, Biobin 500 mg/5 ml Injection 5 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Biobin 500 mg/5 ml Injection 5 ml may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dark-coloured urine, stomach pain, hair loss, dizziness, weakness, and pain at the site of injection, prescribed by your doctor. Most of these side effects of Biobin 500 mg/5 ml Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer Biobin 500 mg/5 ml Injection 5 ml. Hence, do not self-administer.

If you are allergic to Biobin 500 mg/5 ml Injection 5 ml, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with Biobin 500 mg/5 ml Injection 5 ml. Biobin 500 mg/5 ml Injection 5 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had kidney or liver disease. Avoid alcohol consumption with Biobin 500 mg/5 ml Injection 5 ml as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Biobin 500 mg/5 ml Injection 5 ml may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out.

Uses of Biobin 500 mg/5 ml Injection 5 ml

Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia.

Medicinal Benefits Mweb

Medicinal Benefits

Biobin 500 mg/5 ml Injection 5 ml contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for cell growth, repair and multiplication. Thus, Biobin 500 mg/5 ml Injection 5 ml stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Directions for Use

Your oncology doctor will administer Biobin 500 mg/5 ml Injection 5 ml. Hence, do not self-administer.

Side Effects of Biobin 500 mg/5 ml Injection 5 ml

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dark-coloured urine
  • Dizziness
  • Confusion
  • Stomach pain
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

Biobin 500 mg/5 ml Injection 5 ml should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Biobin 500 mg/5 ml Injection 5 ml. Biobin 500 mg/5 ml Injection 5 ml is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid taking Biobin 500 mg/5 ml Injection 5 ml if you are pregnant, as it may harm the foetus. Avoid alcohol consumption with Biobin 500 mg/5 ml Injection 5 ml as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Biobin 500 mg/5 ml Injection 5 ml may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Biobin 500 mg/5 ml Injection 5 ml as it may cause infection.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Biobin 500 mg/5 ml Injection 5 ml:
The combined use of cladribine with Biobin 500 mg/5 ml Injection 5 ml can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Biobin 500 mg/5 ml Injection 5 ml and Cladribine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
How does the drug interact with Biobin 500 mg/5 ml Injection 5 ml:
Taking thalidomide together with Biobin 500 mg/5 ml Injection 5 ml may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Biobin 500 mg/5 ml Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Biobin 500 mg/5 ml Injection 5 ml:
Taking Tofacitinib with Biobin 500 mg/5 ml Injection 5 ml may increase the risk of serious infection.

How to manage the interaction:
Taking Tofacitinib with Biobin 500 mg/5 ml Injection 5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
How does the drug interact with Biobin 500 mg/5 ml Injection 5 ml:
Taking Biobin 500 mg/5 ml Injection 5 ml with Ketoconazole can increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between Biobin 500 mg/5 ml Injection 5 ml and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
How does the drug interact with Biobin 500 mg/5 ml Injection 5 ml:
Coadministration of Biobin 500 mg/5 ml Injection 5 ml with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Biobin 500 mg/5 ml Injection 5 ml and Baricitinib, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Biobin 500 mg/5 ml Injection 5 ml:
When Etanercept is used with Biobin 500 mg/5 ml Injection 5 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Biobin 500 mg/5 ml Injection 5 ml with Etanercept together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Biobin 500 mg/5 ml Injection 5 ml:
Combining Biobin 500 mg/5 ml Injection 5 ml with Clozapine can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Biobin 500 mg/5 ml Injection 5 ml and Clozapine, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - such as fever, sore throat, or muscle aches - contact your doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Biobin 500 mg/5 ml Injection 5 ml:
Combining Infliximab with Biobin 500 mg/5 ml Injection 5 ml can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Biobin 500 mg/5 ml Injection 5 ml with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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  • CHOLERA VACCINE
  • TYPHOID VACCINE

Habit Forming

No

Special Advise

  • Regular blood tests are recommended while taking Biobin 500 mg/5 ml Injection 5 ml to monitor the number and type of cells in the blood. 
  • Biobin 500 mg/5 ml Injection 5 ml, like other cytotoxic medicines, can cause hyperuricemia due to the fast lysis of neoplastic cells. Blood uric acid levels should be monitored and be ready to utilize any supportive or pharmacologic interventions that may be required to address this condition.

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Biobin 500 mg/5 ml Injection 5 ml as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

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