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  3. Brivarise 50 mg Injection 5 ml

Brivarise 50 mg Injection 5 ml, Pack of 1
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Composition :

BRIVARACETAM-10MG/ML

Manufacturer/Marketer :

Galaxus Pharmaceuticals

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Brivarise 50 mg Injection 5 ml

Brivarise 50 mg Injection 5 ml belongs to a group of medications called 'anti-convulsants'. It is used for treating partial-onset seizures (seizures involving only one part of the brain) in people with epilepsy (fits) in patients one month of age and older. Partial-onset seizures are characterized by abnormal electrical activity in only one brain hemisphere. Common symptoms are involuntary muscle contractions, followed by relaxation on one side of the body, uncontrolled head or eye movements, rapid heart rate, and a tingling sensation on the skin.

Brivarise 50 mg Injection 5 ml contains '‘Brivaracetam' that reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, Brivarise 50 mg Injection 5 ml decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures.

Brivarise 50 mg Injection 5 ml will be administered by a qualified healthcare professional. In some cases, you may experience certain common side effects such as somnolence (excess sleepiness), dizziness, fatigue (feeling overtired), nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Brivarise 50 mg Injection 5 ml for as long as your doctor has prescribed. Brivarise 50 mg Injection 5 ml should be gradually withdrawn, so please do not stop taking Brivarise 50 mg Injection 5 ml without consulting your doctor. Before taking the Brivarise 50 mg Injection 5 ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you are pregnant or planning to become pregnant. You should not breastfeed unless the doctor advises. Consult your doctor immediately if you experience suicidal tendencies. It is recommended not to drive or operate machinery as Brivarise 50 mg Injection 5 ml may cause tiredness and fatigue. It is recommended not to take alcoholic beverages while on Brivaracetam therapy.

Uses of Brivarise 50 mg Injection 5 ml

Partial-onset seizures

Directions for Use

Brivarise 50 mg Injection 5 ml will be administered by a qualified healthcare professional. Do not self-administer.

Medicinal Benefits

Brivarise 50 mg Injection 5 ml belongs to a group of medicines called anticonvulsants or anti-epileptics used to control partial-onset seizures in the treatment of epilepsy (fits). Brivarise 50 mg Injection 5 ml consists of ‘Brivaracetam' that works by reducing the electrical impulses and subsequent firing of the nerve impulses that cause fits. Brivarise 50 mg Injection 5 ml decreases the brain's excessive and abnormal nerve activity, thereby helping control seizures.

Storage

Keep Brivarise 50 mg Injection 5 ml out of reach and sight of children.
Side effects of Brivarise 50 mg Injection 5 ml
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

Before taking the Brivarise 50 mg Injection 5 ml, inform your doctor about all your medical conditions, allergic conditions, and all medications you are using. Inform your doctor if you are pregnant or planning to become pregnant. If you become pregnant while taking Brivarise 50 mg Injection 5 ml, call your doctor. You should not breastfeed unless the doctor advises. Consult your doctor immediately if you experience suicidal tendencies. It is recommended not to drive or operate machinery as Brivarise 50 mg Injection 5 ml may cause tiredness and fatigue. It is recommended not to take alcoholic beverages while on Brivaracetam therapy. Do not stop Brivarise 50 mg Injection 5 ml without first talking to a healthcare provider. Stopping Brivarise 50 mg Injection 5 ml suddenly can cause serious problems. Sometimes, it may lead to seizures that will not stop (status epilepticus).

Drug-Drug Interactions

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BrivaracetamKetamine
Severe
BrivaracetamEsketamine
Severe

Drug-Drug Interactions

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BrivaracetamKetamine
Severe
How does the drug interact with Brivarise 50 mg Injection 5 ml:
Co-administration of Brivarise 50 mg Injection 5 ml with Ketamine may increase side effects such as drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is a possible interaction between Brivarise 50 mg Injection 5 ml and Ketamine, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - feeling dizzy, sleepy, confused, having trouble focusing, feeling too relaxed, or having trouble breathing - make sure to contact adoctor right away. Do not stop using any medications without talking to a doctor.
BrivaracetamEsketamine
Severe
How does the drug interact with Brivarise 50 mg Injection 5 ml:
Co-administration of Brivarise 50 mg Injection 5 ml with Esketamine may increase side effects such as drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is an interaction, Brivarise 50 mg Injection 5 ml can be taken with Esketamine if prescribed by the doctor. Consult the prescriber if you notice drowsiness, difficulty concentrating, confusion, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not discontinue the medication without consulting a doctor
BrivaracetamBrimonidine
Moderate
How does the drug interact with Brivarise 50 mg Injection 5 ml:
Brimonidine may be absorbed into the bloodstream and occasionally produce central nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Concomitant use of Brivarise 50 mg Injection 5 ml with brimonidine may increase the risk of these side effects.

How to manage the interaction:
Although there is an interaction Brivarise 50 mg Injection 5 ml can be taken with brimonidine if prescribed by the doctor. Consult the prescriber if you notice dizziness, drowsiness, and difficulty concentrating.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

ANTICONVULSANT

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:48 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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BRIVARACETAM-10MG/MLSymptoms and signs involving emotional state
Moderate
BRIVARACETAM-10MG/MLOther chronic obstructive pulmonary disease
Moderate

Drug-Diseases Interactions

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BRIVARACETAM-10MG/MLSymptoms and signs involving emotional state
Moderate
How does the disease interact with Brivarise 50 mg Injection 5 ml:
Brivarise 50 mg Injection 5 ml which treat epilepsy, have been linked to an elevated risk of suicidal ideas or actions in individuals taking them for any reason. A dosage reduction or therapy termination should be taken into consideration if patients exhibit signs of suicidal ideation or behaviour.

How to manage the interaction:
Anti-epileptic drugs have been associated with an increased risk of suicidal thoughts or behavior. It should be administered with caution in patients with depression or other psychiatric disorders. Consult the doctor if you notice signs and symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts or behavior. If patients have symptoms of suicidal ideation or behavior, a dosage reduction or treatment discontinuation should be considered.
BRIVARACETAM-10MG/MLOther chronic obstructive pulmonary disease
Moderate
How does the disease interact with Brivarise 50 mg Injection 5 ml:
Patients taking Brivarise 50 mg Injection 5 ml have been documented to experience bronchospasm and angioedema, and a hypersensitive reaction to this medication could put patients at danger. Brivarise 50 mg Injection 5 ml should be used with caution in patients who are prone to bronchospasm and angioedema.

How to manage the interaction:
Bronchospasm (tightening of muscles in the airways) and angioedema (swelling) have been reported in patients taking Brivarise 50 mg Injection 5 ml. Caution is advised when using Brivarise 50 mg Injection 5 ml in patients with bronchospasm and angioedema.
BRIVARACETAM-10MG/MLHepatic failure, not elsewhere classified
Moderate
How does the disease interact with Brivarise 50 mg Injection 5 ml:
In the liver, Brivarise 50 mg Injection 5 ml is largely metabolised via hydrolysis. In comparison to matched healthy controls, Brivarise 50 mg Injection 5 ml exposure increased by 50%, 57%, and 59%, respectively, in adult patients with hepatic cirrhosis and Child-Pugh categories A, B, and C. According to the manufacturer's prescription, dosage adjustment is advised for all stages of hepatic impairment due to increases in Brivarise 50 mg Injection 5 ml exposure. When administering this medication to patients with liver illness, caution and close observation are advised.

How to manage the interaction:
Dosage adjustment is recommended for all stages of hepatic impairment. Care and close monitoring is advised when using this medicine in patients with liver disease.
BRIVARACETAM-10MG/MLUnspecified kidney failure
Moderate
How does the disease interact with Brivarise 50 mg Injection 5 ml:
Patients with compromised renal function do not require dose modifications. As there are no data in this patient population, Brivarise 50 mg Injection 5 ml is not advised for use in patients with end-stage renal disease receiving dialysis.

How to manage the interaction:
The use of Brivarise 50 mg Injection 5 ml is not recommended in patients with end-stage renal disease undergoing dialysis as there are no data in this patient population.

FAQs

Brivarise 50 mg Injection 5 ml contains Brivaracetam, an antiepileptic that attaches itself to specific sites (SV2A) on nerve cell surfaces. This activity may suppress the brain's abnormal activity and prevents the spread of electrical signals that cause seizures.

No, Brivarise 50 mg Injection 5 ml should not be stopped even if you start feeling better. Suddenly stopping the Brivarise 50 mg Injection 5 ml may cause continuous seizures, which can be difficult to control. To treat your condition effectually, continue taking Brivarise 50 mg Injection 5 ml for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Brivarise 50 mg Injection 5 ml; your doctor will gradually reduce the dose to avoid precipitating seizures.

Brivarise 50 mg Injection 5 ml may cause suicidal thoughts such as killing or harming yourself. People taking Brivarise 50 mg Injection 5 ml should be closely monitored for suicidal thoughts or behaviour. Speak with your doctor immediately if you need to.

Pay close attention to any changes in mood, behaviour, thoughts, or feelings, especially if they are sudden.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • LEVETIRACETAM
  • RIFAMPIN
  • BUPRENORPHINE
  • PROPOXYPHENE
  • ESKETAMINE
  • SODIUM OXYBATE
  • KETAMINE

Special Advise

  • Pay close attention to any changes in mood, behaviour, thoughts, or feelings, especially if they are sudden.
  • Maintain all scheduled follow-up appointments with your healthcare practitioner.

Disease/Condition Glossary

Partial-onset seizures: Partial-onset seizures are characterized by abnormal electrical activity in only one brain hemisphere. Common symptoms are involuntary muscle contractions, followed by relaxation on one side of the body, Hallucinations, uncontrolled head or eye movements, rapid heart rate, and a tingling sensation on the skin. The symptoms vary in each patient depending on the part of the brain affected.

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