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  1. Home
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  3. Brufen MR Capsule 10's

Brufen MR Capsule 10's, Pack of 10 CapsuleS
Written By ,
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Composition :

IBUPROFEN-400MG + TIZANIDINE-2MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Brufen MR Capsule

Brufen MR Capsule belongs to the class of medications called ‘analgesics’ used in treating acute muscle spasms associated with low back pain. Low back pain, also called lumbago, is a condition that affects the lower portion of the spine. It often occurs due to injury, strain, or sprain in the muscles, bones, or ligaments present in the lower back. In most cases, the only symptom of this condition is a pain in the lower back.

Brufen MR Capsule contains Ibuprofen and Tizanidine. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing prostaglandins' production (chemical substances that cause pain and inflammation) at the affected site (muscle) and reduce pain. Tizanidine is a short-acting muscle relaxant. It works by reducing the activity of the nerves in the brain that control muscles. This effect helps to reduce muscle spasms, thereby improving pain and muscle movements.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Brufen MR Capsule are drowsiness, tiredness, dizziness, low blood pressure, dry mouth, nausea, stomach upset, heartburn, abdominal pain, indigestion, and decrease or increase in heart rate. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Brufen MR Capsule if you are allergic to ibuprofen, tizanidine, NSAIDs, or any contents of this medicine. Do not take Brufen MR Capsule if you have bleeding or ulcers in the stomach or intestine, severe liver, kidney, or heart problems, severe dehydration (due to vomiting or diarrhoea), active bleeding (including in the brain), and conditions that cause the abnormal formation of red blood cells. It is not recommended for use in children, adolescents, pregnant women, and breastfeeding mothers. It should be used with caution in elderly people as dose adjustments are necessary. Alcohol consumption may increase the risk of side-effects. Brufen MR Capsule may cause drowsiness and dizziness, so do not drive or operate heavy machinery if you are fully alert.

Uses of Brufen MR Capsule

Low back pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Brufen MR Capsule is used to treat acute pain associated with muscle spasms that usually occur due to muscle strains, sprains or injuries in the lower back. It contains ibuprofen and tizanidine. Ibuprofen can reduce pain, swelling and inflammation in the muscles, whereas tizanidine can reduce muscle spasms and pain.  It provides fast relief from pain, within a few hours after taking this medicine. It reduces muscle stiffness and enables the easy movement of the muscle. It is well tolerated when taken at recommended doses. For the best results, rest and physical therapy are also essential along with this medicine as it will help to strengthen your back.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking Brufen MR Capsule , inform your doctor if you have any liver, kidney, or heart problems, diabetes, high cholesterol, high blood pressure, respiratory problems, systemic lupus erythematosus (a skin disease), porphyria (an inherited blood disorder), blood clotting problems, and ulcerative colitis (inflammation of the colon). Brufen MR Capsule increases the risk of ulcers, bleeding, and perforation in the stomach or intestine when taken in high doses. It may also increase the risk of heart attack or stroke when used in high doses. Brufen MR Capsule may increase the risk of kidney damage, especially in patients who have liver, kidney, or heart problems, and who are taking water pills. Brufen MR Capsule may affect the function of platelets (form clots) and prolong bleeding time, so it should be used with caution in patients with blood clotting problems. Brufen MR Capsule is an anti-inflammatory and can mask the symptoms of an infection, so consult your doctor if you feel unwell while using this medicine.

Drug-Drug Interactions

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IbuprofenKetorolac
Critical
IbuprofenMeloxicam
Critical

Drug-Drug Interactions

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IbuprofenKetorolac
Critical
How does the drug interact with Brufen MR Capsule:
Taking Ketorolac and Brufen MR Capsule can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac and Brufen MR Capsule together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMeloxicam
Critical
How does the drug interact with Brufen MR Capsule:
Combining Meloxicam and Brufen MR Capsule can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Meloxicam and Brufen MR Capsule together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
TizanidineZiprasidone
Critical
How does the drug interact with Brufen MR Capsule:
Co-administration of Brufen MR Capsule with Ziprasidone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Brufen MR Capsule with Ziprasidone is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
TizanidineCiprofloxacin
Critical
How does the drug interact with Brufen MR Capsule:
Coadministration of Ciprofloxacin and Brufen MR Capsule together can increase the risk of side effects.

How to manage the interaction:
Using Ciprofloxacin and Brufen MR Capsule together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
TizanidineDronedarone
Critical
How does the drug interact with Brufen MR Capsule:
Coadministration of Brufen MR Capsule with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Brufen MR Capsule with Dronedarone is generally avoided as it can result in an interaction, it can be taken when prescribed by a doctor. If you experience sudden dizziness, shortness of breath, palpitations, or chest pain, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TizanidineFluvoxamine
Critical
How does the drug interact with Brufen MR Capsule:
Taking Fluvoxamine with Brufen MR Capsule it can increases the risk of side effects.

How to manage the interaction:
Although Fluvoxamine with Brufen MR Capsule is not recommended, but can be taken together if prescribed by a doctor. However, if you experience drowsiness, dizziness, low blood pressure, slurred speech, confusion, or severe weakness, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TizanidineSaquinavir
Critical
How does the drug interact with Brufen MR Capsule:
Combining Brufen MR Capsule with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Brufen MR Capsule with Saquinavir is not recommended, as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TizanidineCisapride
Critical
How does the drug interact with Brufen MR Capsule:
Coadministration of Brufen MR Capsule with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Brufen MR Capsule with Cisapride is avoided as it can result in an interaction, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience sudden dizziness, shortness of breath, palpitations, or vomiting. Do not discontinue any medications without consulting your doctor.
IbuprofenTinzaparin
Severe
How does the drug interact with Brufen MR Capsule:
The combined use of Tinzaparin and Brufen MR Capsule can increase the risk of bleeding complications.

How to manage the interaction:
Co-administration of Tinzaparin and Brufen MR Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenTolmetin
Severe
How does the drug interact with Brufen MR Capsule:
The combined use of Tolmetin and Brufen MR Capsule can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Co-administration of Tolmetin and Brufen MR Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear, and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Deep tissue massages with the help of muscle massagers are considered helpful.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well and get optimal sleep (at least 8 hours for adults).
  • Hot or cold therapy can help treat muscle spasms.
  • Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
  • Try to include glycine (protein) in your daily diet, which is good food for your muscle.

Habit Forming

No

Therapeutic Class

ANALGESICS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Brufen MR Capsule contains Ibuprofen and Tizanidine. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing prostaglandins' production (chemical substances that cause pain and inflammation) at the affected site (muscle) and reduce pain. Tizanidine is a short-acting muscle relaxant. It works by reducing the activity of the nerves in the brain that control muscles. It helps to reduce muscle spasms, thereby improving pain and muscle movements. Together, Brufen MR Capsule can effectively reduce low back pain.

Brufen MR Capsule is probably safe and well-tolerated in diabetic patients when taken at recommended doses. However, higher doses or prolonged use may affect sugar levels and cause unwanted effects. So, let your doctor know that you have diabetes before taking Brufen MR Capsule .

Brufen MR Capsule may cause drowsiness and dizziness. So, it is advised not to consume alcohol as it may cause excessive drowsiness. It is also not advised to drive or operate heavy machinery if you are not fully alert.

Brufen MR Capsule may cause kidney damage when taken in high doses for a long duration. So, do not increase the dose or use it for prolonged periods than intended by the doctor.

Brufen MR Capsule should not be used in patients with stomach ulcers as it may elevate the symptoms and worsen the condition. So, inform your doctor that you have a stomach ulcer before taking this medicine.

Drug-Drug Interactions Checker List

  • WARFARIN
  • HEPARIN
  • CLOPIDOGREL
  • TICLOPIDINE
  • AMIODARONE
  • MEXILETINE
  • PROPAFENONE
  • CIMETIDINE
  • ENOXACIN
  • PEFLOXACIN
  • NORFLOXACIN
  • ATENOLOL
  • PROPRANOLOL
  • DIGOXIN
  • TEMAZEPAM
  • METHOTREXATE
  • PHENYTOIN
  • LITHIUM
  • PAROXETINE
  • SERTRALINE
  • CHOLESTYRAMINE
  • ZIDOVUDINE
  • RITONAVIR
  • PROBENECID
  • BACLOFEN
  • VORICONAZOLE
  • FLUCONAZOLE
  • ROFECOXIB

Disease/Condition Glossary

Low back pain: It is also called lumbago. It is a common condition that occurs due to injury, sprain, or strain to the muscles, bones, or ligaments present in the lower portion of the spine. The common causes are lack of regular exercise, improper postural lifting, bad or poor posture, and fracture. Pain in the lower back is the only symptom often seen with this condition. Analgesics (pain relievers) and physical therapy can help to relieve pain. Exercise helps in muscle stretching so that they are less likely to spasm, tear and sprain.

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