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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - CAF0019

Author Details

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About CAFIRATE SOLUTION

Uses of CAFIRATE SOLUTION

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of CAFIRATE SOLUTION

Drug Warnings

Drug-Drug Interactions

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CaffeineLinezolid
Critical
CaffeinePhenelzine
Critical

Drug-Drug Interactions

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CaffeineLinezolid
Critical
How does the drug interact with Cafirate Solution 1.5ml:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Cafirate Solution 1.5ml with Linezolid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeinePhenelzine
Critical
How does the drug interact with Cafirate Solution 1.5ml:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Cafirate Solution 1.5ml with Phenelzine is not recommended, please consult your doctor before taking it. They can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
Critical
How does the drug interact with Cafirate Solution 1.5ml:
Coadministration of tranylcypromine with Cafirate Solution 1.5ml can in cause severe high blood pressure.

How to manage the interaction:
Taking Cafirate Solution 1.5ml with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, and sudden numbness or weakness (especially on one side of the body). Do not discontinue any medications without consulting a doctor.
CaffeineIsocarboxazid
Critical
How does the drug interact with Cafirate Solution 1.5ml:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Cafirate Solution 1.5ml with Isocarboxazid is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
CaffeineCocaine
Severe
How does the drug interact with Cafirate Solution 1.5ml:
Coadministration of Cafirate Solution 1.5ml with cocaine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Cafirate Solution 1.5ml can be taken with cocaine if prescribed by the doctor. However, contact your doctor if you experience dizziness, lightheadedness, palpitations, and shortness of breath. Do not discontinue using any medication without contacting a doctor.
CaffeineTizanidine
Severe
How does the drug interact with Cafirate Solution 1.5ml:
Coadministration of Cafirate Solution 1.5ml with Tizanidine may increase the blood levels and effects of tizanidine. This may cause excessive blood pressure, especially when rising from a sitting or lying position.

How to manage the interaction:
Although there is an interaction, Cafirate Solution 1.5ml can be taken with tizanidine if prescribed by the doctor. Contact your doctor if you experience dizziness, excessive sweating, or palpitations. Do not stop using any medicine without consulting your doctor.
CaffeineDipyridamole
Severe
How does the drug interact with Cafirate Solution 1.5ml:
Concomitant use of Cafirate Solution 1.5ml with dipyridamole may decrease the effects of dipyridamole.

How to manage the interaction:
Although there is an interaction, Cafirate Solution 1.5ml can be taken with dipyridamole if prescribed by the doctor. Avoiding Cafirate Solution 1.5ml for 12 to 24 hours before dipyridamole administration is advised.
CaffeineEsketamine
Severe
How does the drug interact with Cafirate Solution 1.5ml:
Esketamine can cause increase in blood pressure and using it with Cafirate Solution 1.5ml may increase the risk.

How to manage the interaction:
Although there is a possible interaction between Cafirate Solution 1.5ml and Esketamine, it can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting your doctor.
CaffeineBupropion
Severe
How does the drug interact with Cafirate Solution 1.5ml:
Bupropion and Cafirate Solution 1.5ml can increase blood pressure. Concomitant use may have additive effects.

How to manage the interaction:
Although there is an interaction, Cafirate Solution 1.5ml can be taken with bupropion if prescribed by the doctor. Regular monitoring of blood pressure is advised.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CAFFEINE CITRATE-20MGComplications and ill-defined descriptions of heart disease
Severe
CAFFEINE CITRATE-20MGEssential (primary) hypertension
Severe

Drug-Diseases Interactions

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CAFFEINE CITRATE-20MGComplications and ill-defined descriptions of heart disease
Severe
How does the disease interact with Cafirate Solution 1.5ml:
Patients with considerable cardiovascular impairment, such as uncompensated heart failure, severe coronary disease, or severe hypertension, should not utilise CNS stimulants.

How to manage the interaction:
It is contraindicated in patients with significant heart problems. Before initiation of therapy, a careful assessment of the the patient's cardiac status should be done.
CAFFEINE CITRATE-20MGEssential (primary) hypertension
Severe
How does the disease interact with Cafirate Solution 1.5ml:
The use of CNS stimulant drugs may be contraindicated in people with severe hypertension since they have been found to raise blood pressure.

How to manage the interaction:
CNS stimulants may increase blood pressure. Therefore, caution should be used when administering to patients with preexisting high blood pressure and other cardiovascular conditions.
CAFFEINE CITRATE-20MGOther diseases of liver
Severe
How does the disease interact with Cafirate Solution 1.5ml:
The liver substantially metabolises CNS stimulants. Patients with compromised hepatic function may see a decrease in their plasma clearance and an extension of their half-life.

How to manage the interaction:
Cafirate Solution 1.5ml should be administered cautiously in patients with moderate to severe liver disease, and the dosage should be adjusted accordingly.
CAFFEINE CITRATE-20MGMental disorder, not otherwise specified
Severe
How does the disease interact with Cafirate Solution 1.5ml:
The use of CNS stimulants can increase symptoms of mental disorder and behaviour disturbance as well as create psychotic or manic symptoms, suicidal ideation, violence, and suicidal behaviour.

How to manage the interaction:
CNS stimulants may cause psychotic or maniac symptoms, suicidal ideation, aggression and can exacerbate symptoms of behavior disturbance and thought disorder. Patients should be monitored closely, specially during treatment initiation and at times of dose changes.
CAFFEINE CITRATE-20MGGastritis and duodenitis
Severe
How does the disease interact with Cafirate Solution 1.5ml:
Peptic acid secretion has been known to be stimulated by methylxanthines. In patients with active peptic ulcer disease, therapy with products containing methylxanthines should be delivered with the utmost caution.

How to manage the interaction:
It should be administered with extreme caution in patients with active peptic ulcer disease.
CAFFEINE CITRATE-20MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Cafirate Solution 1.5ml:
Overall, it is advised to use caution when administering CNS stimulants to patients who have severely compromised renal function because the therapeutic response may be affected by the decreased rate of excretion.

How to manage the interaction:
It should be administered with caution in patients with significantly impaired kidney function. The dosage should be adjusted accordingly.

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