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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Composition :

DIAZEPAM-10MG

Manufacturer/Marketer :

Ranbaxy Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANXIOLYTICS]

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - CAL0054

Author Details

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FAQs

Calmpose Injection 5 x 2 ml works by increasing levels of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. This helps to relieve anxiety and stops seizure attacks (fits), and relaxes tense muscles.

Using Calmpose Injection 5 x 2 ml in patients with sleep apnoea syndrome (a condition where breathing stops for a short period of time when a person is sleeping) is contraindicated. So, it is advisable to inform the doctor if you are suffering from sleep apnoea syndrome.

Caffeine is a stimulant that may reduce the calming effects of Calmpose Injection 5 x 2 ml . So, it is advisable to avoid the intake of caffeinated beverages like coffee, tea, cola or chocolate that contain caffeine. Avoid grapefruit juice as it may increase the amount of Calmpose Injection 5 x 2 ml in blood.

Calmpose Injection 5 x 2 ml usage is not recommended in people with hypersensitivity to diazepam, people with a phobia (a fear of a particular object or situation), difficulty breathing, porphyria (a disorder of the blood), sleep apnoea syndrome, acute narrow-angle glaucoma, and open-angle glaucoma unless the patient is receiving appropriate treatment.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

Intake of alcohol can increase the side effects of Calmpose Injection 5 x 2 ml , like dizziness, drowsiness, and difficulty concentrating. In a few cases, people may also experience impaired thinking and judgment. Hence, avoid consuming alcohol while being treated with Calmpose Injection 5 x 2 ml .

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Pregnancy

Consult your doctor

Calmpose Injection 5 x 2 ml is recommended in pregnancy if clearly necessary, Inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Calmpose Injection 5 x 2 ml .

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Breast Feeding

Consult your doctor

Calmpose Injection 5 x 2 ml may not be recommended in breastfeeding as it may harm your infant. Inform your doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Calmpose Injection 5 x 2 ml .

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Driving

Safe if prescribed

Calmpose Injection 5 x 2 ml may cause a reduction in mental awareness, affect concentration and may cause dizziness. Hence, avoid driving after receiving Calmpose Injection 5 x 2 ml .

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Liver

Consult your doctor

Calmpose Injection 5 x 2 ml is not recommended for use in people with severe liver disease. Inform your doctor if you have a history of liver disease or an ongoing liver problem. Your doctor may adjust the dose of Calmpose Injection 5 x 2 ml if necessary.

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Kidney

Consult your doctor

Inform your doctor if you have kidney problems or a history of kidney disease. Your doctor may adjust your dose depending upon your kidney condition.

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Children

Safe if prescribed

The safety and effectiveness of Calmpose Injection 5 x 2 ml in neonates (30 days or less) have not been established. Your paediatrician will recommend this medicine based on the condition of your child.

About Calmpose Injection 5 x 2 ml

Calmpose Injection 5 x 2 ml belongs to a group of medications called benzodiazepine used to treat anxiety, muscle spasms, and epilepsy/seizures/fits. It can also be used as a sedative during surgery or dental procedure. Besides this, it is also used to manage alcohol withdrawal symptoms like agitation, tremor, or hallucinations. An anxiety disorder is a mental condition characterized by feelings of excessive fear or worry that affect an individual's daily activities.

Calmpose Injection 5 x 2 ml contains diazepam, which works by increasing levels of the calming chemical mediator known as gamma-aminobutyric acid (GABA) in the brain; this helps relieve anxiety, stops seizure attacks (fits) and relaxes the tense muscles.

Calmpose Injection 5 x 2 ml will be administered by a healthcare professional; do not self-administer. Sometimes, Calmpose Injection 5 x 2 ml may cause side effects, such as drowsiness, fatigue, confusion, unsteadiness, or dizziness. Most of these side effects of Calmpose Injection 5 x 2 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have lung disease, muscle weakness (myasthenia gravis), sleeping disorder, severe liver disease, or problems with alcohol consumption or other prescription recreational drugs. Inform your doctor if you are pregnant or breastfeeding. Do not drive or operate machinery as Calmpose Injection 5 x 2 ml may reduce mental alertness. It is advisable to avoid alcohol after taking this medicine to prevent adverse effects such as dizziness, drowsiness, and difficulty concentrating.

Uses of Calmpose Injection 5 x 2 ml

Anxiety, muscle spasms, epilepsy/seizures/fits, sedation, alcohol withdrawal syndrome.

Medicinal Benefits Mweb

Key Benefits

Calmpose Injection 5 x 2 ml belongs to a group of medications called benzodiazepine used to treat anxiety, muscle spasms, and epilepsy/seizures/fits. It can also be used as a sedative during surgery or dental procedure. Besides this, it is also used to manage alcohol withdrawal symptoms like agitation, tremor, or hallucinations. Calmpose Injection 5 x 2 ml contains diazepam, which works by increasing levels of the calming chemical mediator known as gamma-aminobutyric acid (GABA) in the brain; this helps relieve anxiety, stops seizure attacks (fits) and relaxes the tense muscles.

Directions for Use

Calmpose Injection 5 x 2 ml will be administered by a qualified healthcare professional. Kindly do not self-administer.

Side Effects of Calmpose Injection 5 x 2 ml

  • Drowsiness
  • Feeling sleepy (sedation)
  • Light-headedness
  • Unsteadiness, or dizziness
  • Confusion

Drug Warnings

Calmpose Injection 5 x 2 ml is not recommended for people with hypersensitivity to diazepam, other related benzodiazepines or any components present in Calmpose Injection 5 x 2 ml , people with a phobia (a fear of a particular object or situation), difficulty breathing, porphyria (a disorder of the blood brought on by a buildup of specific substances connected to the proteins in red blood cells), liver impairment, muscle weakness (myasthenia gravis), open-angle glaucoma or acute narrow-angle glaucoma unless patients are receiving appropriate therapy. Inform your doctor if you have suicidal thoughts, difficulty concentrating, sleep disorders, depression, breathing problems, history of alcohol/drug abuse, arteriosclerosis (narrowing of the blood vessels), lung, kidney, liver or heart problems. Concomitant use of opioids and benzodiazepines may result in profound sedation, respiratory depression, coma, and death.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Calmpose Injection 5 x 2 ml :
Using Morphine together with Calmpose Injection 5 x 2 ml can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Calmpose Injection 5 x 2 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Calmpose Injection 5 x 2 ml with tramadol may cause serious side effects like respiratory distress or coma.

How to manage the interaction:
Consult the doctor if you are taking Calmpose Injection 5 x 2 ml and tramadol. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Calmpose Injection 5 x 2 ml :
Taking Calmpose Injection 5 x 2 ml together with olanzapine can cause low blood pressure, weak pulse, shallow breathing, muscle weakness, drowsiness, dizziness and slurred speech.

How to manage the interaction:
Combining Olanzapine and Calmpose Injection 5 x 2 ml can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms consult the doctor immediately. Avoid activities requiring mental alertness until you know how these medications will affect you. Do not stop using any medications without first talking to your doctor.
DiazepamSufentanil
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Sufentanil with Calmpose Injection 5 x 2 ml can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Calmpose Injection 5 x 2 ml with Sufentanil can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - feeling tired or sleepy, having trouble breathing, or a slower heartbeat - make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
DiazepamCodeine
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Calmpose Injection 5 x 2 ml with codeine may cause serious side effects.

How to manage the interaction:
Consult your doctor if you are using Calmpose Injection 5 x 2 ml and codeine. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Nalbuphine with Calmpose Injection 5 x 2 ml can make the side effects worse or more dangerous.

How to manage the interaction:
Although there is a possible interaction between Calmpose Injection 5 x 2 ml and Nalbuphine, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
DiazepamRemifentanil
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Co-administration of Remifentanil with Calmpose Injection 5 x 2 ml can increase the seriousness of side effects.

How to manage the interaction:
Although taking Calmpose Injection 5 x 2 ml and Remifentanil together can evidently cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your health and talk to your doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Calmpose Injection 5 x 2 ml :
Taking Calmpose Injection 5 x 2 ml together with fluvoxamine may cause an increase in side effects such as drowsiness, confusion, muscle weakness, and fainting.

How to manage the interaction:
Although there is a possible interaction, Calmpose Injection 5 x 2 ml can be taken with fluvoxamine if prescribed by the doctor. However, if you experience any unusual symptoms consult your doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Calmpose Injection 5 x 2 ml :
Taking Calmpose Injection 5 x 2 ml and fentanyl together can increase the risk of side effects.

How to manage the interaction:
Although taking Fentanyl together with Calmpose Injection 5 x 2 ml can result in an interaction, they can be taken together if prescribed by your doctor. However, consult a doctor if you have sleepiness, difficulty concentrating, and impaired judgment. Do not stop taking any medication without consulting your doctor.
DiazepamEthanol
Severe
How does the drug interact with Calmpose Injection 5 x 2 ml :
Drinking alcohol while taking Calmpose Injection 5 x 2 ml can make you feel more sleepy and slow down your brain and body.

How to manage the interaction:
Although there is a possible interaction between Ethanol and Calmpose Injection 5 x 2 ml , you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - problems with your brain or nerves, feeling dizzy, feeling sleepy or having trouble focusing - make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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DIAZEPAM-10MGMyasthenia gravis and other myoneural disorders
Severe
DIAZEPAM-10MGEssential (primary) hypertension
Severe

Drug-Diseases Interactions

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DIAZEPAM-10MGMyasthenia gravis and other myoneural disorders
Severe
How does the disease interact with Calmpose Injection 5 x 2 ml :
Calmpose Injection 5 x 2 ml shouldn't be used by people with myasthenia gravis.

How to manage the interaction:
The use of Calmpose Injection 5 x 2 ml is not recommended in patients with myasthenia gravis (an autoimmune disease).
DIAZEPAM-10MGEssential (primary) hypertension
Severe
How does the disease interact with Calmpose Injection 5 x 2 ml :
Injecting benzodiazepines into individuals who are in shock or a coma is not advised. In these patients, the hypnotic and hypotensive effects of these drugs may last longer and be more potent.

How to manage the interaction:
The hypnotic (sleep-inducing) and hypotensive (lowering blood pressure) effects of these agents may be prolonged and intensified. The medicine should not be administered to patients in shock or coma.
DIAZEPAM-10MGEpilepsy
Severe
How does the disease interact with Calmpose Injection 5 x 2 ml :
The incidence of generalised tonic-clonic seizures (grand mal) or their onset may be accelerated in people with seizure disorders who use benzodiazepines.

How to manage the interaction:
Benzodiazepines may increase the occurrence of seizures. Dose adjustment or initiation of appropriate anticonvulsant medication may be needed. Do not discontinue medication without first consulting with the physician.
DIAZEPAM-10MGAbnormalities of breathing
Severe
How does the disease interact with Calmpose Injection 5 x 2 ml :
When administered in large doses and/or by intravenous administration, benzodiazepines have the potential to cause respiratory depression and apnea.

How to manage the interaction:
Usually when given in high dosages and/or by intravenous administration, benzodiazepines may cause respiratory depression and apnea. Therapy with benzodiazepines should be administered cautiously in these patients.
DIAZEPAM-10MGOther diseases of liver
Severe
How does the disease interact with Calmpose Injection 5 x 2 ml :
The liver breaks down benzodiazepines, and the metabolites are then eliminated in the urine. The oxidative N-dealkylation of chlordiazepoxide, clorazepate, Calmpose Injection 5 x 2 ml , flurazepam, and quazepam results in active metabolites that have significantly longer half-lives than the parent substance.

How to manage the interaction:
Benzodiazepines are metabolized by the liver. Therapy with benzodiazepines should be administered cautiously at lower initial dosages in patients with impaired liver function.
DIAZEPAM-10MGMental and behavioural disorders due to multiple drug use and use of other psychoactive substances
Severe
How does the disease interact with Calmpose Injection 5 x 2 ml :
It is possible for benzodiazepines to lead to abuse and dependence. Particularly with repeated usage and/or high dosages, tolerance and physical and psychological dependence may develop.

How to manage the interaction:
Benzodiazepines have the potential to cause dependence and abuse. It should be used with caution in patients with addiction- prone individuals, such as those with a history of alcohol or substance abuse. The dose should be gradually reduced if dependency is suspected.
DIAZEPAM-10MGGlaucoma
Severe
How does the disease interact with Calmpose Injection 5 x 2 ml :
The makers believe that using benzodiazepines while a patient has acute angle-closure glaucoma or untreated open-angle glaucoma is contraindicated.

How to manage the interaction:
Benzodiazepine is not recommended in patients with acute angle-closure glaucoma or untreated open-angle glaucoma.
DIAZEPAM-10MGMental and behavioural disorders due to use of alcohol
Severe
How does the disease interact with Calmpose Injection 5 x 2 ml :
Alcohol and benzodiazepines should not be combined. Vital signs are decreased in alcohol-intoxicated patients.

How to manage the interaction:
The use of benzodiazepines with alcohol is not recommended. Therapy with benzodiazepines should be administered cautiously in patients who might be prone to acute alcohol intake.

Drug-Drug Interactions Checker List

  • FLUOXETINE
  • CLOZAPINE
  • CETIRIZINE
  • ERYTHROMYCIN
  • SUXAMETHONIUM
  • TUBOCURARINE
  • MORPHINE
  • PHENOBARBITAL
  • HYDROCHLOROTHIAZIDE
  • HYDRALAZINE
  • CIMETIDINE
  • OMEPRAZOLE
  • CARBAMAZEPINE
  • PRIMIDONE
  • AMPRENAVIR
  • RITONAVIR
  • LEVODOPA
  • KETAMINE
  • THEOPHYLLINE
  • LOFEXIDINE
  • NABILONE
  • RIFAMPICIN
  • DISULFIRAM
  • PHENYTOIN

Habit Forming

Yes

Special Advise

  • The use of Calmpose Injection 5 x 2 ml may increase the risk of misuse, abuse, and addiction.  Therefore, before prescribing Calmpose Injection 5 x 2 ml and throughout the treatment, the patient's risk for misuse, abuse, and addiction should be assessed.
  • Calmpose Injection 5 x 2 ml may cause withdrawal symptoms if treatment is stopped suddenly. Therefore, the dose should be gradually reduced to prevent withdrawal symptoms.

 

Diet & Lifestyle Advise

  • Yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction can help improve your mindfulness.
  • De-stress by meditating, reading books, taking a nice bubble bath, or listening to relaxing music.
  • Regular exercise can help reduce anxiety by generating endorphins and enhancing your sleep and self-image.
  • Drink plenty of water to keep hydrated.
  • Include a diet rich in whole grains, vegetables, and fruits.
  • Limit your consumption of alcohol, coffee, added sugar, salt, and fat.

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