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Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

CANAGLIFLOZIN-100MG

Manufacturer/Marketer :

Elder Projects Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANTIDIABETICS

Country of origin

India

Manufacturer/Marketer address

Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai 400053.
Other Info - CAN0825

Author Details

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FAQs

Canagliflozin 100 Tablet 10's is a type of medicine known as a sodium-glucose cotransporter-2 (SGLT2) inhibitor used for the treatment of type -2 diabetes. It lowers blood sugar levels by blocking the action of SGLT-2 in the kidney and removing excess sugar from your body through urination.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Type 2 diabetes is a common form of diabetes in which the blood sugar-lowering hormone called insulin produced by the body does not function properly. Thus, the blood glucose level increases, and symptoms such as frequent urination, increased thirst, and increased hunger start. Diabetes, if left untreated or not treated properly, can cause long-term complications such as nerve damage, kidney damage, eye damage, and foot problems, and poses a high risk of developing heart disease.

Canagliflozin 100 Tablet 10's is safe to take before driving as it does not affect your thinking ability. Do not drive or operate machinery if you experience dizziness or drowsiness.

Do not stop taking Canagliflozin 100 Tablet 10's until your prescribed course is finished, even if you feel better.

Canagliflozin 100 Tablet 10's is only prescribed for the treatment of type 2 diabetes, also called 'non-insulin-dependent diabetes.

Once blood sugar goes below the normal range (70mg/dl), it is called hypoglycemia or low blood sugar in people with diabetes. If you feel your sugar level is going down and feel weak, immediately eat sugar candies. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you if you have diabetes.

Disclaimer

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Alcohol

Unsafe

You should avoid consuming alcohol with Canagliflozin 100 Tablet 10's as it may alter your blood sugar levels or lead to serious side effects.

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Pregnancy

Caution

No sufficient data are available on the use of Canagliflozin 100 Tablet 10's in pregnancy. Canagliflozin 100 Tablet 10's is a Category C pregnancy drug that is not recommended for use in pregnancy. Hence, consult your doctor before taking this medicine.

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Breast Feeding

Caution

There is no sufficient data on how Canagliflozin 100 Tablet 10's affects breastfeeding. It is safe to seek medical advice before you start Canagliflozin 100 Tablet 10's if you are breastfeeding.

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Driving

Caution

Canagliflozin 100 Tablet 10's is safe to take before driving as it does not affect your thinking ability. Do not drive or operate machinery if you experience dizziness or drowsiness.

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Liver

Caution

If you have liver disease or a history of liver impairment, consult your doctor before taking Canagliflozin 100 Tablet 10's. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have kidney disease or a history of kidney impairment, consult your doctor before taking Canagliflozin 100 Tablet 10's. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Caution

Canagliflozin 100 Tablet 10's is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

About Canagliflozin 100 Tablet 10's

Canagliflozin 100 Tablet 10's belongs to the category of medicines called 'anti-diabetic' primarily used for managing and treating type 2 diabetes, especially in persons whose sugar levels are too high and cannot be controlled only by dieting and exercising. Type 2 diabetes is a condition that occurs when there is either less insulin or available insulin is not properly utilized by our body cells for lowering raised blood glucose. It is the most common type of diabetes, accounting for around 90% of diabetes cases found commonly in middle-aged people. So it is also called adult-onset diabetes or non-insulin-dependent diabetes mellitus (NIDDM).

Canagliflozin 100 Tablet 10's contains “Canagliflozin” is a sodium-glucose cotransporters-2 (SGLT-2) (a protein present in the kidney) inhibitor that works by inhibiting the reabsorption of glucose in the body, resulting in an increase in glucose excretion through urine. The removal of excessive glucose helps to lower the blood sugar level. Additionally, it also lowers high blood pressure, due to increased diuretic effect (water loss) and reduced body weight due to a reduction in glucose availability.

Take Canagliflozin 100 Tablet 10's as prescribed. Your doctor will advise you how often you take Canagliflozin 100 Tablet 10's based on your medical condition. In some cases, you may experience urinary tract infections, changes in urination (including urinating more frequently or in larger amounts, urgent need to urinate, need to urinate at night), constipation, feeling thirsty, nausea, dizziness, and nausea. Most of these side effects of Canagliflozin 100 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Canagliflozin 100 Tablet 10's, let your doctor know if you are pregnant or planning to get pregnant, or breastfeeding. And also, tell the doctor if you have/had any medical history of heart, liver, or kidney diseases. Inform your doctor about all the medicine you are taking and your health condition to rule out any unpleasant side effects. Canagliflozin 100 Tablet 10's works best when coupled with a healthy lifestyle like losing weight if you are overweight (BMI>25), eating fewer calories (low fat and sugary food), and being more physically active (at least 150min of activity every week).

Uses of Canagliflozin 100 Tablet 10's

Type 2 Diabetes Mellitus

Medicinal Benefits Mweb

Medicinal Benefits

Canagliflozin 100 Tablet 10's belongs to the group of medicines called “anti-diabetic” indicated in the treatment of type 2 diabetes or non-insulin-dependent diabetes (NIDDM). This medicine is primarily prescribed to persons with high blood sugar levels and is not controlled by diet and exercise alone. Canagliflozin 100 Tablet 10's consists of “Canagliflozin” is a sodium-glucose cotransporter-2 (SGLT-2) inhibitor responsible for the inhibition of SGLT-2 enzymes in the kidney. It prevents the reabsorption of glucose from the blood filtered through your kidney, thereby increasing the glucose excretion from your body when you pee. In some cases, Canagliflozin 100 Tablet 10's can cause weight loss in diabetic persons by increasing the excretion of excess sugar through urination when you pee.

Directions for Use

Take Canagliflozin 100 Tablet 10's as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, break, or chew it.

Side Effects of Canagliflozin 100 Tablet 10's

  • Urinary tract infections
  • Changes in urination (including urinating more frequently or in larger amounts, urgent need to urinate, need to urinate at night)
  • Constipation
  • Feeling thirsty
  • Nausea
  • Blood tests may show changes in blood fat (cholesterol) levels
  • Increases in the number of red blood cells in your blood

Drug Warnings

Canagliflozin 100 Tablet 10's should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Before you start taking Canagliflozin 100 Tablet 10's, tell your doctor if you have serious heart disease or if you have had a stroke, low blood pressure (hypotension), and severe liver or kidney disease. Canagliflozin 100 Tablet 10's, when used with insulin, $ name may lower the blood sugar level, leading to hypoglycemia, which can be fatal. Your doctor may adjust the dose by lowering the dose of insulin or Canagliflozin 100 Tablet 10's in this case. If you experience rapid weight loss, feeling sick or being sick, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to your breath, a sweet or metallic taste in your mouth, or a different odour to your urine or sweat, talk to a doctor or go to the nearest hospital immediately.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Canagliflozin 100 Tablet 100 Tablet:
Co-administration of Canagliflozin 100 Tablet with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Canagliflozin 100 Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Canagliflozin 100 Tablet 100 Tablet:
Co-administration of Morphine with Canagliflozin 100 Tablet may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Canagliflozin 100 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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CANAGLIFLOZIN-100MGHerbal products/medicines
Moderate

Drug-Food Interactions

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CANAGLIFLOZIN-100MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Concomitant use of Canagliflozin 100 Tablet with St. John's Wort may decrease the serum concentration of Canagliflozin 100 Tablet. Consult the prescriber, the doctor may adjust the dose of Canagliflozin 100 Tablet if you are taking St.John's wort.

Drug-Diseases Interactions

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CANAGLIFLOZIN-100MGOther diseases of liver
Severe
CANAGLIFLOZIN-100MGOther disorders of kidney and ureter, not elsewhere classified
Severe

Drug-Diseases Interactions

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CANAGLIFLOZIN-100MGOther diseases of liver
Severe
How does the disease interact with Canagliflozin 100 Tablet 100 Tablet:
Due to a lack of clinical data, the SGLT2 inhibitors ertugliflozin and Canagliflozin 100 Tablet are not advised for use in patients with severe hepatic impairment. It is advised to exercise caution when using dapagliflozin in patients with severe hepatic impairment. Patients with mild or moderate hepatic impairment do not require dosage modifications.

How to manage the interaction:
Canagliflozin 100 Tablet is not recommended for use in patients with severe hepatic impairment due to a lack of clinical data.
CANAGLIFLOZIN-100MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Canagliflozin 100 Tablet 100 Tablet:
In patients with deteriorating renal function, the glucose-lowering benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors are reduced. In addition, those who have impaired renal function (eGFR less than 60 mL/min/1.73 m2), those who are elderly, and those on loop diuretics may be more susceptible to deleterious effects of volume depletion like hypotension and acute kidney injury.

How to manage the interaction:
The glucose-lowering effects of the medicine may be decreased in patients with worsening kidney function. Renal function should be evaluated prior to treatment initiation and monitored regularly in at-risk patients.
CANAGLIFLOZIN-100MGHypotension
Moderate
How does the disease interact with Canagliflozin 100 Tablet 100 Tablet:
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors cause intravascular volume contraction which may lead to symptomatic hypotension after treatment initiation especially in the elderly, in patients with impaired renal function, patients with low systolic blood pressure, or those using diuretics . Volume status should be assessed and corrected before starting treatment and patients should be monitored during therapy.

How to manage the interaction:
Low blood pressure might occur in patients with impaired renal function, patients with low systolic blood pressure, or those using diuretics. Patients should be monitored during therapy.
CANAGLIFLOZIN-100MGBacterial infection of unspecified site
Moderate
How does the disease interact with Canagliflozin 100 Tablet 100 Tablet:
The usage of sodium-glucose cotransporter 2 (SGLT-2) inhibitors has been linked to an increased risk of genital mycotic infections. When administering this medication to patients who have a history of genital mycotic infections or who have not undergone circumcision, caution should be taken because they are more susceptible to experience genital mycotic infections. Observe and treat as necessary.

How to manage the interaction:
Genital mycotic infections may occur. Care should be exercised in patients who have a history of genital mycotic infections or who are uncircumcised as these patients are more likely to develop genital mycotic infections. Monitoring the patient for infections is advised.

Drug-Drug Interactions Checker List

  • GLIMEPIRIDE
  • GLIPIZIDE
  • FUROSEMIDE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • EFAVIRENZ
  • RITONAVIR
  • RIFAMPICIN
  • CHOLESTYRAMINE
  • DABIGATRAN
  • DIGOXIN

Habit Forming

No

Special Advise

You should have a test of glycated haemoglobin (HbA1C) every 3 months to check your blood glucose level control.

Diet & Lifestyle Advise

  • A person should engage themself in regular exercise like cycling, running, walking, jogging, dancing, or swimming for at least 30 minutes. Try to invest at least 150 minutes weekly in exercise.
  • A person should also maintain a healthy body weight to avoid obesity or high blood sugar; it can increase the risk of the onset of diabetes.
  • A person should take low fat and a low sugar diet. For that, replace carbohydrates with whole grains, fruits, and vegetables as carbohydrates changed into sugars leading to high blood sugar levels.
  • Try to avoid potatoes as they are high glycaemic foods that increase the risk of high sugar in the blood.
  • A person should limit the consumption of alcohol and quit smoking.
  • Keep your blood pressure as normal (120/80) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Do not take stress as it may elevate your blood sugar level. You can adopt stress management techniques like mindfulness to control stress-related blood sugar changes.

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