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  3. Carbozest 450 Injection 45 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

CARBOPLATIN-10MG

Manufacturer/Marketer :

Zee Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

Uchani, G.T. Road, Karnal-132001 Haryana (India).
Other Info - CAR1679

FAQs

Carbozest 450 Injection contains 'Carboplatin'. Carboplatin works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.

Yes, Carbozest 450 Injection can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.

Carbozest 450 Injection should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.

Before you receive treatment with Carbozest 450 Injection, tell your doctor about all of your medical conditions. You should not receive Carbozest 450 Injection if you are allergic to carboplatin or any contents in Carbozest 450 Injection. It should not be employed in patients with severe bone marrow depression or significant bleeding.

If not given an inappropriate dose, Carbozest 450 Injection can cause toxic effects, although not everyone gets it. So, Carbozest 450 Injection is prescribed by a doctor experienced in the use of medications to treat cancer only.

Avoid taking Carbozest 450 Injection if you are pregnant because Carbozest 450 Injection can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Carbozest 450 Injection.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Carbozest 450 Injection. It could lead to avoiding unpleasant side effects.

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Pregnancy

Unsafe

Carbozest 450 Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Carbozest 450 Injection and at least six months afterwards. Please consult your doctor about any concerns regarding this.

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Breast Feeding

Unsafe

Carbozest 450 Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers. Please consult your doctor about any concerns regarding this.

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Driving

Caution

Carbozest 450 Injection may affect your reactions and your ability to drive. Possible side effects of chemotherapy with Carbozest 450 Injection may occur, such as nausea and vomiting. If you are affected by these side effects, you should not drive and/or operate machines that require you to be alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Carbozest 450 Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Carbozest 450 Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Unsafe

Efficacy and safety have not been established. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing them.

About Carbozest 450 Injection

Carbozest 450 Injection belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Carbozest 450 Injection contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

Carbozest 450 Injection is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of Carbozest 450 Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Carbozest 450 Injection for as long as your doctor has prescribed. Do not stop the Carbozest 450 Injection midway. Talk to your doctor before taking Carbozest 450 Injection if you have severe allergic reactions to Carbozest 450 Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carbozest 450 Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carbozest 450 Injection if you are pregnant or breastfeeding because this Carbozest 450 Injection can cause harmful effects on the unborn baby. Both women and men using this Carbozest 450 Injection should use birth control to avoid pregnancy.

Uses of Carbozest 450 Injection

Ovarian cancer and Small cell lung cancer

Medicinal Benefits Mweb

Medicinal Benefits

Carbozest 450 Injection contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

Directions for Use

Parenteral: Carbozest 450 Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Side Effects of Carbozest 450 Injection

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Hair loss and numbness
  • Tingling
  • Burning
  • Pain in the hands or feet
  • Nephrotoxicity at high doses
  • Electrolyte disturbances
  • Thrombocytopenia (low blood platelet count)
  • Peripheral neuropathy (nerves malfunction)
  • Leukopenia (low white blood cell count)

Drug Warnings

Carbozest 450 Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Carbozest 450 Injection. To treat your condition effectually, continue taking Carbozest 450 Injection for as long as your doctor has prescribed. Do not stop the Carbozest 450 Injection midway. Talk to your doctor before taking Carbozest 450 Injection if you have severe allergic reactions to Carbozest 450 Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carbozest 450 Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carbozest 450 Injection if you are pregnant or breastfeeding because this Carbozest 450 Injection can cause harmful effects on the unborn baby. Both women and men using this Carbozest 450 Injection should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Carbozest 450 Injection treatment and appropriate until recovery is achieved.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Carbozest 450 Injection 45 ml:
Co-administration of Sorafenib with Carbozest 450 Injection 45 ml can increase the risk or severity of serious side effects.

How to manage the interaction:
Taking Sorafenib with Carbozest 450 Injection 45 ml together is not recommended as it can cause an interaction, consult a doctor before taking it. However if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Carbozest 450 Injection 45 ml:
Using cladribine and Carbozest 450 Injection 45 ml together can increase the risk of serious infections.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml and cladribine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, red or inflamed skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
CarboplatinBacitracin
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Taking Carbozest 450 Injection 45 ml and bacitracin can increase the risk of nephrotoxicity(kidney damage).

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml and bacitracin can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult the doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Carbozest 450 Injection 45 ml:
Using Carbozest 450 Injection 45 ml with Thiotepa can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Thiotepa and Carbozest 450 Injection 45 ml, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Carbozest 450 Injection 45 ml:
Using Carbozest 450 Injection 45 ml with Fingolimod can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Carbozest 450 Injection 45 ml and Fingolimod, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Carbozest 450 Injection 45 ml:
Taking Carbozest 450 Injection 45 ml with thalidomide can increase the risk of blood clots.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml with thalidomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you experience chest pain, breathing difficulty, coughing up blood, and pain, redness, or swelling in an arm or leg, sudden loss of vision, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Carbozest 450 Injection 45 ml:
Taking Carbozest 450 Injection 45 ml with etanercept may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml and etanercept can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm (mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Carbozest 450 Injection 45 ml:
Co-administration of leflunomide with Carbozest 450 Injection 45 ml can increase the risk of infections.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml with leflunomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm(mucous secretion), red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Carbozest 450 Injection 45 ml:
When Carbozest 450 Injection 45 ml is used with topotecan, it may increase the risk of side effects.

How to manage the interaction:
Co-administration of Carbozest 450 Injection 45 ml with clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting your doctor.
CarboplatinCertolizumab
Severe
How does the drug interact with Carbozest 450 Injection 45 ml:
Using Carbozest 450 Injection 45 ml with Certolizumab can increase the risk of developing serious infections.

How to manage the interaction:
Taking Carbozest 450 Injection 45 ml with Certolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CARBOPLATIN-10MGOther and unspecified infectious diseases
Moderate
CARBOPLATIN-10MGOther disorders of kidney and ureter, not elsewhere classified
Moderate

Drug-Diseases Interactions

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CARBOPLATIN-10MGOther and unspecified infectious diseases
Moderate
How does the disease interact with Carbozest 450 Injection 45 ml:
Antineoplastic drugs regularly can, to variable degrees, promote myelosuppression due to their cytotoxic effects on rapidly growing tissues.

How to manage the interaction:
If you experience any signs or symptoms suggesting infection such as fever, sore throat, or local infection during antineoplastic therapy, immediately consult your doctor. Close clinical monitoring of hematopoietic function is recommended.
CARBOPLATIN-10MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Carbozest 450 Injection 45 ml:
The kidney is the main organ used to remove Carbozest 450 Injection 45 ml. Patients with a creatinine clearance of less than 60 mL/min had lower total body and renal clearance of Carbozest 450 Injection 45 ml.

How to manage the interaction:
If you have any kidney related problems, do not forget to mention it to your doctor, a close monitoring is required.
CARBOPLATIN-10MGHaemorrhage, not elsewhere classified
Mild
How does the disease interact with Carbozest 450 Injection 45 ml:
Patients who have substantial bleeding should not use Carbozest 450 Injection 45 ml. Both severe myelosuppression and dose-dependent thrombocytopenia are brought on by Carbozest 450 Injection 45 ml.

How to manage the interaction:
The use of Carbozest 450 Injection 45 ml is not advisable if you have significant bleeding. If you experience any signs or symptoms suggesting bleeding such as petechiae, purpura, epistaxis, hemoptysis, hematuria, and melena, consult your doctor. Close clinical monitoring of hematopoietic function is recommended.

Drug-Drug Interactions Checker List

  • PEMETREXED
  • GEMCITABINE
  • PEGFILGRASTIM
  • PACLITAXEL
  • PANTOPRAZOLE
  • AMIKACIN
  • GENTAMICIN
  • KANAMYCIN
  • STREPTOMYCIN
  • TOBRAMYCIN
  • DOCETAXEL

Habit Forming

No

Special Advise

  • Peripheral blood counts should be frequently monitored during carboplatin treatment and, when appropriate, until recovery is achieved.
  • Carbozest 450 Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Carbozest 450 Injection.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Carbozest 450 Injection may make your skin sensitive to sunlight.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

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