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  3. Castramid 50 mg Tablet 10's

Prescription drug
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Castramid 50 mg Tablet 10's, Pack of 10 TabletS
Castramid 50 mg Tablet 10's, Pack of 10 TabletS
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Composition :

BICALUTAMIDE-50MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - CAS0117

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:34 AM IST

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Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Interaction of Castramid 50mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Castramid 50mg Tablet .

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Pregnancy

Unsafe

Castramid 50mg Tablet is contraindicated in pregnant women as it is not approved for use in women. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Castramid 50mg Tablet is contraindicated in breastfeeding women as it is not approved for use in women. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Castramid 50mg Tablet may cause drowsiness in some people. Therefore, avoid driving if you are drowsy after taking Castramid 50mg Tablet .

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Liver

Caution

Take Castramid 50mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

Castramid 50mg Tablet is safe to use in patients with kidney problems if prescribed by a doctor.

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Children

Unsafe

Castramid 50mg Tablet is not recommended for children as the safety and effectiveness were not established.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.2052.pdf
  2. https://www.drugs.com/cdi/bicalutamide.html

About Castramid 50mg Tablet

Castramid 50mg Tablet belongs to the class of anticancer drugs called non-steroidal anti-androgens used to treat prostate cancer. Prostate cancer is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.

Castramid 50mg Tablet contains Bicalutamide which works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Castramid 50mg Tablet prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor.

Take Castramid 50mg Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience weakness, skin rash, swelling and tenderness of the breast, nausea, dry skin, weight gain, hair loss, hot flushes (sudden feeling of warmth), anemia (lack of blood), reduces sex drive, constipation, depression, indigestion or dizziness. Most of these side effects of Castramid 50mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Castramid 50mg Tablet or any other medicines, please tell your doctor. Castramid 50mg Tablet is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Castramid 50mg Tablet . Please consult a doctor if you want to father a child before taking Castramid 50mg Tablet as it may impair fertility in men. Avoid taking Castramid 50mg Tablet with cisapride, astemizole, or terfenadine. Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Castramid 50mg Tablet may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Castramid 50mg Tablet .

Uses of Castramid 50mg Tablet

Prostate cancer

Medicinal Benefits Mweb

Medicinal Benefits

Castramid 50mg Tablet contains Bicalutamide, an anticancer drug used in the treatment of prostate cancer. Castramid 50mg Tablet works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Castramid 50mg Tablet prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor. Also, Castramid 50mg Tablet relieves difficulty in urination. Castramid 50mg Tablet can be used in combination with radiation therapy to treat prostate cancer where cancer has spread from the prostate gland to the surrounding tissues.

Directions for Use

Take Castramid 50mg Tablet with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not crush, chew or break it.

Side Effects of Castramid 50mg Tablet

  • Weakness
  • Skin rash
  • Swelling and tenderness of breast
  • Nausea
  • Dry skin
  • Weight gain
  • Hair loss
  • Hot flushes (sudden feeling of warmth)
  • Anaemia (lack of blood)
  • Reduced sex drive
  • Constipation
  • Depression
  • Indigestion
  • Dizziness

Drug Warnings

If you are allergic to Castramid 50mg Tablet or any other medicines, please tell your doctor. Castramid 50mg Tablet is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Castramid 50mg Tablet . You and your partner recommend using effective birth control measures while taking Castramid 50mg Tablet and for 130 days after discontinuing Castramid 50mg Tablet . Please consult a doctor if you want to father a child before taking Castramid 50mg Tablet as it may impair fertility in men. You are advised to quit smoking as it may increase the risk of prostate cancer. Avoid taking Castramid 50mg Tablet with cisapride, astemizole, or terfenadine. Regular tests are recommended to monitor liver function and if there is any severe disturbance in liver functioning, avoid taking Castramid 50mg Tablet . Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Castramid 50mg Tablet may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Castramid 50mg Tablet .

Drug-Drug Interactions

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BicalutamideSaquinavir
Critical
BicalutamideZiprasidone
Critical

Drug-Drug Interactions

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BicalutamideSaquinavir
Critical
How does the drug interact with Castramid 50 mg Tablet:
When Castramid 50 mg Tablet is taken with Saquinavir, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Saquinavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideZiprasidone
Critical
How does the drug interact with Castramid 50 mg Tablet:
Taking Castramid 50 mg Tablet and Ziprasidone can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Castramid 50 mg Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
BicalutamideThioridazine
Critical
How does the drug interact with Castramid 50 mg Tablet:
Taking Castramid 50 mg Tablet with Thioridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Thioridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamidePimozide
Critical
How does the drug interact with Castramid 50 mg Tablet:
When Castramid 50 mg Tablet is taken with Pimozide, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Pimozide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideDronedarone
Critical
How does the drug interact with Castramid 50 mg Tablet:
When Castramid 50 mg Tablet is taken with Dronedarone, can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Dronedarone is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideMesoridazine
Critical
How does the drug interact with Castramid 50 mg Tablet:
Taking Castramid 50 mg Tablet with Mesoridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Mesoridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideHalofantrine
Critical
How does the drug interact with Castramid 50 mg Tablet:
Taking Castramid 50 mg Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet with Halofantrine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideOlaparib
Severe
How does the drug interact with Castramid 50 mg Tablet:
When Castramid 50 mg Tablet is taken with Olaparib, it can increase the blood levels and effects of Olaparib.

How to manage the interaction:
Although there is a possible interaction between Castramid 50 mg Tablet and Olaparib, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
BicalutamideDofetilide
Severe
How does the drug interact with Castramid 50 mg Tablet:
Co-administration of Castramid 50 mg Tablet and Dofetilide together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet and Dofetilide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
BicalutamideToremifene
Severe
How does the drug interact with Castramid 50 mg Tablet:
Co-administration of Castramid 50 mg Tablet and Toremifene together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Castramid 50 mg Tablet and Toremifene together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CISAPRIDE
  • ASTEMIZOLE
  • TERFENADINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • QUINIDINE
  • MOXIFLOXACIN
  • METHADONE
  • WARFARIN
  • CICLOSPORIN
  • CIMETIDINE
  • KETOCONAZOLE

Habit Forming

No

Special Advise

Regular blood tests are recommended to monitor changes in blood and liver functioning while taking Castramid 50mg Tablet .

Diet & Lifestyle Advise

  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products as they may increase prostate cancer risk.
  • Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
  • Quit smoking to reduce the risk of prostate cancer.

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