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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Composition :

CEFUROXIME-50MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cefoprit 1.5Gm Inj

Cefoprit 1.5Gm Inj belongs to the class of cephalosporin antibiotics indicated to treat a wide range of bacterial infections including lower respiratory tract infections, urinary tract infections, skin and skin structure infections, septicemia (blood infection), meningitis (infection of brain and spinal cord), gonorrhoea (sexually transmitted infections), bone and joint infections. Cefoprit 1.5Gm Inj is also used to prevent infections during surgery. 

Cefoprit 1.5Gm Inj is a broad-spectrum antibiotic that acts against a wide range of bacteria. It works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby kills the bacteria and treats bacterial infection.

A healthcare expert will administer Cefoprit 1.5Gm Inj; do not self-administer. In some cases, Cefoprit 1.5Gm Inj may cause side effects such as diarrhoea, nausea, vomiting, pain, and swelling at the site of injection. Most of these side effects do not require medical attention and resolve over time. However, if the side effects persist or worsen, consult your doctor.

Let your doctor know about your medical condition and the medications you are taking to avoid the occurrence of potential interactions. Consult your doctor if you are pregnant, breastfeeding, suspect you are pregnant or plan to have a baby; your doctor will weigh the benefits of Cefoprit 1.5Gm Inj therapy against the risk to your baby. Cefoprit 1.5Gm Inj may cause dizziness, so drive only if you are alert.

Uses of Cefoprit 1.5Gm Inj

Bacterial infections

Directions for Use

Cefoprit 1.5Gm Inj will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Cefoprit 1.5Gm Inj is used to treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, Cefoprit 1.5Gm Inj is also used to prevent infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. Cefoprit 1.5Gm Inj is a broad-spectrum antibiotic that acts against a wide range of bacteria. It works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby kills the bacteria and treats bacterial infection.

Storage

Keep out of sight and reach of children.

Drug Warnings

Do not take Cefoprit 1.5Gm Inj if you are allergic to any of the contents. Consult your doctor if you are pregnant or breastfeeding. Inform your doctor if you have kidney or liver problems. Cefoprit 1.5Gm Inj may cause Clostridioides difficile-associated diarrhoea (CDAD). If you experience a severe, persistent diarrhoea, or if you find blood or mucus in stools, consult your doctor immediately. Let your doctor know about your medical condition and the medications you are taking to avoid the occurrence of potential interactions.

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
CefuroximeLepirudin
Severe

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
How does the drug interact with Cefoprit 1.5Gm Inj:
Co-administration of Cefoprit 1.5Gm Inj may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Cefoprit 1.5Gm Inj. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Cefoprit 1.5Gm Inj:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Cefoprit 1.5Gm Inj.

How to manage the interaction:
Although taking Cefoprit 1.5Gm Inj and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cefoprit 1.5Gm Inj:
Co-administration of Dalteparin and Cefoprit 1.5Gm Inj can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Cefoprit 1.5Gm Inj with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cefoprit 1.5Gm Inj:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After completing the course of Cefoprit 1.5Gm Inj, probiotics should be taken to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. 
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Cefoprit 1.5Gm Inj.
  • Avoid intake of alcoholic beverages with Cefoprit 1.5Gm Inj as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Cefoprit 1.5Gm Inj in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Author Details

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Drug-Diseases Interactions

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CEFUROXIME-50MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
CEFUROXIME-50MGChronic kidney disease
Moderate

Drug-Diseases Interactions

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CEFUROXIME-50MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
How does the disease interact with Cefoprit 1.5Gm Inj:
Colitis: In some cases the use of Cefoprit 1.5Gm Inj may cause ranging from mild diarrhea to fatal colitis. Colitis is commonly Clostridioides difficile-associated diarrhea (CDAD). Discontinue therapy if signs of CDAD are confirmed.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Cefoprit 1.5Gm Inj should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the colon) or pseudomembranous colitis (a severe inflammation of the inner lining of the large intestine). Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFUROXIME-50MGChronic kidney disease
Moderate
How does the disease interact with Cefoprit 1.5Gm Inj:
Renal dysfunction: Cefoprit 1.5Gm Inj is eliminated by the kidney in an unchanged form. Thus the plasma levels of the drug increase and prolongs the half-life. Adjust the doses of Cefoprit 1.5Gm Inj as necessary.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised during prolonged or high-dose therapy.
CEFUROXIME-50MGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Cefoprit 1.5Gm Inj:
Dialysis : Most of the antibiotics are eliminated by hemodialysis. Therefore, administer Cefoprit 1.5Gm Inj after dialysis or an additional dosage to be administered.

How to manage the interaction:
Cefoprit 1.5Gm Inj serum levels may be decreased by hemodialysis and peritoneal dialysis. Supplemental doses should be given at the end of each hemodialysis session.
CEFUROXIME-50MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Cefoprit 1.5Gm Inj:
seizure disorders: In some patients, seizures were reported with whom renal dysfunction which incase of dosage adjustment was not done. Discontinue Cefoprit 1.5Gm Inj if seizures are reported.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Cefoprit 1.5Gm Inj should be discontinued if seizures associated with drug therapy occur.
CEFUROXIME-50MGOther diseases of liver
Moderate
How does the disease interact with Cefoprit 1.5Gm Inj:
liver disease: With Cefoprit 1.5Gm Inj, a transient increase in the AST, ALT, and alkaline phosphatase levels was observed. Use with caution and closely monitor for hepatic function is recommended.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disease as cases of hepatitis have been reported with the use of certain cephalosporins.
CEFUROXIME-50MGOther diseases of liver
Moderate
How does the disease interact with Cefoprit 1.5Gm Inj:
Rarely, cephalosporins use may cause hypoprothrombinemia, with or without bleeding. Monitor for Prothrombin time.

How to manage the interaction:
Cephalosporins may be associated with reduced prothrombin activity/prolonged prothrombin time (blood takes too long to form a clot). Prothrombin time should be monitored in at-risk patients and managed as needed.

FAQs

Cefoprit 1.5Gm Inj works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby kills the bacteria and treats bacterial infection.

After taking an antibiotic, you may need to wait up to three hours before eating or drinking any dairy products, including milk, butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also affect the working of antibiotics.

Cefoprit 1.5Gm Inj is used to treat bacterial infections and does not treat viral infections such as cough, flu or cold.

Cefoprit 1.5Gm Inj may interact with birth control pills and lower its efficiency. Inform your doctor if you use any birth control pills.

Cefoprit 1.5Gm Inj may cause Clostridioides difficile-associated diarrhoea (CDAD). If you experience a severe, persistent diarrhoea, or if you find blood or mucus in stools, consult your doctor immediately. Do not take anti-diarrhoeal medicine on your own.

Drug-Drug Interactions Checker List

  • GENTAMICIN
  • NEOMYCIN
  • FUROSEMIDE
  • PROBENECID
  • WARFARIN
  • LEVONORGESTREL
  • MEDROXYPROGESTERONE
  • BCG VACCINE
  • CHOLERA VACCINE LIVE
  • TYPHOID VACCINE LIVE

Special Advise

  • Regular monitoring of blood count, haemoglobin levels, renal and liver function tests are recommended.
  • Cefoprit 1.5Gm Inj might affect lab test results. Inform the person doing the tests that you are taking Cefoprit 1.5Gm Inj.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

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