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  1. Home
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  3. CELKERAN 5MG TABLET

CELKERAN 5MG TABLET, Pack of 1 TABLET
CELKERAN 5MG TABLET, Pack of 1 TABLET
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
Know More
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Composition :

CHLORAMBUCIL-5MG

Manufacturer/Marketer :

Levin Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

INDIA

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - CEL0075

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

CELKERAN 5MG TABLET contains Chlorambucil, which works by slowing or stopping the growth of cancer cells in your body. Thus, it treats cancer efficiently.

Attend all your doctor's appointments while taking CELKERAN 5MG TABLET to ensure the therapy is effective. Regular blood tests and weight checks must be performed. While taking the CELKERAN 5MG TABLET, both men and women should use an effective means of contraception. Do not use any other medications unless prescribed by the doctor.

Do not stop taking CELKERAN 5MG TABLET on your own. Take CELKERAN 5MG TABLET for as long as your doctor prescribes it, depending on your medical condition. Do not hesitate to speak with your doctor if you experience difficulty taking CELKERAN 5MG TABLET.

Chlorambucil can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment.

Chlorambucil may increase the risk that you will develop other cancers. Talk to your doctor about this risk.

Some dietary changes can help you manage side effects; for example, in case of diarrhoea-Choose foods or drinks with sodium (sports drinks or broth) and potassium (bananas and all-natural fruit juices).

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with CELKERAN 5MG TABLET.

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Pregnancy

Unsafe

CELKERAN 5MG TABLET is not recommended for use during pregnancy, especially in the first trimester. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

CELKERAN 5MG TABLET should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Caution

It is unknown whether CELKERAN 5MG TABLET alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Caution

Patients with liver impairment should be closely monitored for signs and symptoms of toxicity. If you have a pre-existing or a history of liver disease, inform your doctor before taking CELKERAN 5MG TABLET. Your doctor will weigh the benefits and potential risks before prescribing CELKERAN 5MG TABLET.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking CELKERAN 5MG TABLET. Your doctor may titrate the dose if required based on your condition.

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Children

Consult your doctor

CELKERAN 5MG TABLET can be used to treat Hodgkin's disease and non-Hodgkin's lymphomas in children. Please consult your doctor for more information.

Product Substitutes

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Keep Refrigerated. Do not freeze.Prepaid payment required.

Reference

  1. https://www.medsafe.govt.nz/profs/datasheet/l/Leukerantab.pdf
  2. https://issuu.com/tajpharmaceutical/docs/chlorambusil_tablets_2mg_taj_pharma-smpc
  3. https://www.drugs.com/chlorambucil.html
  4. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/chlorambucil
  5. https://reference.medscape.com/drug/leukeran-chlorambucil-342112
  6. https://go.drugbank.com/drugs/DB00291
  7. https://medlineplus.gov/druginfo/meds/a682899.html#:~:text=Expand%20Section,cells%20that%20normally%20fight%20infection).
  8. https://www.cancer.org/cancer/types/chronic-lymphocytic-leukemia/about/what-is-cll.html
  9. https://www.hopkinsmedicine.org/health/conditions-and-diseases/cancer/cancer-diet-foods-to-add-and-avoid-during-cancer-treatment

About CELKERAN 5MG TABLET

CELKERAN 5MG TABLET belongs to a class of cytotoxic drugs, also known as chemotherapeutic agents, primarily used to treat various cancer conditions such as Hodgkin's disease, certain forms of non-Hodgkin's lymphoma, Chronic lymphocytic leukaemia, Waldenstrom's macroglobulinaemia, advanced Ovarian adenocarcinoma and Breast cancer. Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues.

CELKERAN 5MG TABLET contains Chlorambucil, which works by slowing or stopping the growth of cancer cells in the body. Thus, it treats cancer efficiently.

Use CELKERAN 5MG TABLET as directed by your doctor. It may cause side effects, such as a drop in the number of blood cells and platelets, feeling sick (nausea), being sick (vomiting), sores in the mouth and throat, tiredness and missed menstrual periods (in girls and women). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if any of these side effects persist or worsen.

Tell your doctor before prescribing CELKERAN 5MG TABLET if you have a history of bleeding disorders, heart or liver problems, radiation treatment, or any infection. Many other medications can interact with or be impacted by CELKERAN 5MG TABLET, so let your doctor know all your medications. This medicine has been shown to reduce the number of blood cells, making you more susceptible to infections. During treatment with this medication, you will need to have regular blood tests to assess your blood cells, as well as your kidney, liver, and heart function.

Do not take CELKERAN 5MG TABLET if you are allergic (hypersensitive) to Chlorambucil or any of the other ingredients of this medicine. Chlorambucil may increase the risk of developing other cancers. CELKERAN 5MG TABLET can disrupt a woman's natural menstrual cycle (period) and stop sperm production in men. It may induce permanent infertility (difficulty becoming pregnant); If you are pregnant, inform your doctor before starting this medication. It is not recommended for use in the first trimester of pregnancy. Effective birth control measures are advised for men and women while on treatment with this medicine. Call your doctor right away if you become pregnant while taking Chlorambucil. 

Uses of CELKERAN 5MG TABLET

Cancer

Medicinal Benefits Mweb

Medicinal Benefits

CELKERAN 5MG TABLET is a cytotoxic medicine, also known as a chemotherapeutic agent, primarily used to treat various cancer conditions such as Hodgkin's disease, certain forms of non-Hodgkin's lymphoma, Chronic lymphocytic leukaemia, Waldenstrom's macroglobulinaemia, Advanced ovarian adenocarcinoma and breast cancer. Chlorambucil, present in CELKERAN 5MG TABLET, works by slowing or stopping the growth of cancer cells in your body. Thus, it treats cancer efficiently.

Directions for Use

Swallow the medicine as a whole with a glass of water. Do not break, crush or chew the tablet.

Side Effects of CELKERAN 5MG TABLET

  • A drop in the number of blood cells and platelets
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Diarrhoea
  • Mouth ulcers
  • Hair loss
  • Anaemia
  • Convulsions (in children)
  • Bone marrow suppression (bone marrow doesn't make enough blood cells and platelets)

Drug Warnings

Before taking CELKERAN 5MG TABLET, inform your doctor about your medical history and ongoing therapies to rule out potential adverse effects or interactions. Always take CELKERAN 5MG TABLET as prescribed by your doctor. It's crucial to take your medication as directed. The dosage of this medicine is based on your condition. Your doctor may adjust your dose during therapy based on the treatment results. The drug chlorambucil can reduce the number of blood cells in your bone marrow. Your doctor will request laboratory testing before, during, and after therapy to determine whether this drug affects your blood cells. Keep all lab appointments. Before taking CELKERAN 5MG TABLET, inform your doctor if you are pregnant or breastfeeding. If you become pregnant while on treatment with Chlorambucil, tell your doctor.

Drug-Drug Interactions

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ChlorambucilTofacitinib
Severe
ChlorambucilEtanercept
Severe

Drug-Drug Interactions

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ChlorambucilTofacitinib
Severe
How does the drug interact with Celkeran 5mg Tablet:
Taking Tofacitinib with Celkeran 5mg Tablet may increase the risk of serious infection.

How to manage the interaction:
There may be a possibility of interaction between Tofacitinib and Celkeran 5mg Tablet, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blo, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
ChlorambucilEtanercept
Severe
How does the drug interact with Celkeran 5mg Tablet:
When Etanercept is used with Celkeran 5mg Tablet, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Celkeran 5mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
ChlorambucilBaricitinib
Severe
How does the drug interact with Celkeran 5mg Tablet:
Coadministration of baricitinib and Celkeran 5mg Tablet can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Celkeran 5mg Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
ChlorambucilCladribine
Severe
How does the drug interact with Celkeran 5mg Tablet:
The combined Cladribine with Celkeran 5mg Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Celkeran 5mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
ChlorambucilThalidomide
Severe
How does the drug interact with Celkeran 5mg Tablet:
Taking thalidomide together with Celkeran 5mg Tablet may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Celkeran 5mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • BCG VACCINE
  • MUMPS (LIVE ATTENUATED)
  • INFLUENZA VIRUS VACCINE
  • ADALIMUMAB
  • CLOZAPINE
  • DEUCRAVACITINIB
  • CLADRIBINE
  • ETANERCEPT
  • FINGOLIMOD
  • LEFLUNOMIDE

Habit Forming

No

Special Advise

  • When you take CELKERAN 5MG TABLET, your doctor will suggest regular blood tests to monitor the count of blood cells.

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

CELKERAN 5MG TABLET Substitute

Substitutes safety advice

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