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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Composition :

CEFUROXIME-250MG

Manufacturer/Marketer :

Wanbury Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

Other Info - CEM0008

Author Details

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About CEMAX T 250MG TABLET

Uses of CEMAX T 250MG TABLET

Medicinal Benefits Mweb

Key Benefits

Directions for Use

Side Effects of CEMAX T 250MG TABLET

Drug Warnings

Drug-Drug Interactions

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CefuroximeLepirudin
Severe

Drug-Drug Interactions

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How does the drug interact with Cemax T 250mg Tablet:
Co-administration of Dalteparin and Cemax T 250mg Tablet can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Cemax T 250mg Tablet with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Cemax T 250mg Tablet:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Cemax T 250mg Tablet.

How to manage the interaction:
Although taking Cemax T 250mg Tablet and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
CefuroximeBCG vaccine
Severe
How does the drug interact with Cemax T 250mg Tablet:
Co-administration of Cemax T 250mg Tablet may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Cemax T 250mg Tablet. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Cemax T 250mg Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CEFUROXIME-250MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
CEFUROXIME-250MGChronic kidney disease
Moderate

Drug-Diseases Interactions

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CEFUROXIME-250MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
How does the disease interact with Cemax T 250mg Tablet:
Colitis: In some cases the use of Cemax T 250mg Tablet may cause ranging from mild diarrhea to fatal colitis. Colitis is commonly Clostridioides difficile-associated diarrhea (CDAD). Discontinue therapy if signs of CDAD are confirmed.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Cemax T 250mg Tablet should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the colon) or pseudomembranous colitis (a severe inflammation of the inner lining of the large intestine). Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFUROXIME-250MGChronic kidney disease
Moderate
How does the disease interact with Cemax T 250mg Tablet:
Renal dysfunction: Cemax T 250mg Tablet is eliminated by the kidney in an unchanged form. Thus the plasma levels of the drug increase and prolongs the half-life. Adjust the doses of Cemax T 250mg Tablet as necessary.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised during prolonged or high-dose therapy.
CEFUROXIME-250MGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Cemax T 250mg Tablet:
Dialysis : Most of the antibiotics are eliminated by hemodialysis. Therefore, administer Cemax T 250mg Tablet after dialysis or an additional dosage to be administered.

How to manage the interaction:
Cemax T 250mg Tablet serum levels may be decreased by hemodialysis and peritoneal dialysis. Supplemental doses should be given at the end of each hemodialysis session.
CEFUROXIME-250MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Cemax T 250mg Tablet:
seizure disorders: In some patients, seizures were reported with whom renal dysfunction which incase of dosage adjustment was not done. Discontinue Cemax T 250mg Tablet if seizures are reported.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Cemax T 250mg Tablet should be discontinued if seizures associated with drug therapy occur.
CEFUROXIME-250MGOther diseases of liver
Moderate
How does the disease interact with Cemax T 250mg Tablet:
liver disease: With Cemax T 250mg Tablet, a transient increase in the AST, ALT, and alkaline phosphatase levels was observed. Use with caution and closely monitor for hepatic function is recommended.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disease as cases of hepatitis have been reported with the use of certain cephalosporins.
CEFUROXIME-250MGOther diseases of liver
Moderate
How does the disease interact with Cemax T 250mg Tablet:
Rarely, cephalosporins use may cause hypoprothrombinemia, with or without bleeding. Monitor for Prothrombin time.

How to manage the interaction:
Cephalosporins may be associated with reduced prothrombin activity/prolonged prothrombin time (blood takes too long to form a clot). Prothrombin time should be monitored in at-risk patients and managed as needed.

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