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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Composition :

CLADRIBINE-10MG

Manufacturer/Marketer :

Dabur India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

8/3, Asaf Ali Road, New Delhi-110002
Other Info - CLA0132

FAQs

CLADRIM 10MG INJECTION contains Cladribine, which works by inhibiting the production of genetic material (DNA) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes.

It is said that concomitant use of CLADRIM 10MG INJECTION along with live vaccines may cause serious adverse effects. Hence, inform your doctor if you have taken any vaccines recently before receiving CLADRIM 10MG INJECTION.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with CLADRIM 10MG INJECTION. Please consult the doctor.

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Pregnancy

Unsafe

CLADRIM 10MG INJECTION is not recommended for use in pregnancy as it may harm the foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving CLADRIM 10MG INJECTION. You should not become pregnant while on treatment with CLADRIM 10MG INJECTION.

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Breast Feeding

Unsafe

CLADRIM 10MG INJECTION is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. If you are breastfeeding, inform your doctor before receiving CLADRIM 10MG INJECTION. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Not applicable

CLADRIM 10MG INJECTION will be administered to hospitalized patients.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving CLADRIM 10MG INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving CLADRIM 10MG INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

CLADRIM 10MG INJECTION is not recommended for use in children as safety and effectiveness have not been established.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

About CLADRIM 10MG INJECTION

CLADRIM 10MG INJECTION belongs to a group of anticancer medicines called purine analogue used in the treatment of hairy cell leukaemia. Leukaemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. 

CLADRIM 10MG INJECTION contains Cladribine, which belongs to the class of purine antimetabolites. It works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes.

CLADRIM 10MG INJECTION may cause certain side effects such as insomnia, dizziness, cough, abdominal pain, rash, constipation, fatigue, vomiting, nausea, headache, cough, constipation, weakness, and pain at the site of injection. Most of these side effects of CLADRIM 10MG INJECTION do not require medical attention and gradually resolve over time. A trained healthcare professional will administer CLADRIM 10MG INJECTION. Hence, do not self-administer.

If you are allergic to CLADRIM 10MG INJECTION, inform your doctor and avoid receiving it. Inform your doctor about your complete medical and medication history before starting treatment with CLADRIM 10MG INJECTION. CLADRIM 10MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, consult your doctor if you are pregnant, planning to become pregnant or breastfeeding. Let the doctor know if you have/had kidney or liver disease, hemolytic anaemia, or severe bone marrow suppression before starting the treatment, as it may worsen your condition. Inform your doctor if you have received any vaccination before starting the treatment.

Uses of CLADRIM 10MG INJECTION

Hairy cell Leukemia.

Medicinal Benefits Mweb

Medicinal Benefits

CLADRIM 10MG INJECTION contains Cladribine, which is used in the treatment of multiple sclerosis. It works by inhibiting DNA synthesis (responsible for DNA elongation, synthesis, and repair) in cancer cells by interfering with the ribonucleotide reductase and DNA polymerase enzymes. Thus, CLADRIM 10MG INJECTION stops the multiplication of abnormal cells and causes the death of cancer cells.

Directions for Use

An oncology doctor will administer CLADRIM 10MG INJECTION. Self-administration is not recommended.

Side Effects of CLADRIM 10MG INJECTION

  • Nausea
  • Abdominal pain
  • Constipation
  • Weakness
  • Injection site reactions
  • Pain at the site of injection
  • Headache
  • Dizziness
  • Insomnia
  • Anxiety
  • Muscle pain
  • Rash

Drug Warnings

If you are allergic to CLADRIM 10MG INJECTION, inform your doctor and avoid receiving it. Inform your doctor about your complete medical and medication history before starting treatment with CLADRIM 10MG INJECTION. CLADRIM 10MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, consult your doctor if you are pregnant, planning to become pregnant or breastfeeding. Let the doctor know if you have/had kidney or liver disease, haemolytic anaemia, severe bone marrow suppression, thrombocytopenia (low number of platelets), or neutropenia (low white blood cells) before starting the treatment, as it may worsen your condition. If you are about to receive any vaccinations, inform your doctor beforehand, as it may cause infection.

Drug-Drug Interactions

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CladribineInfliximab
Severe
CladribineOfatumumab
Severe

Drug-Drug Interactions

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CladribineInfliximab
Severe
How does the drug interact with Cladrim 10mg Injection:
Combining Infliximab with Cladrim 10mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Cladrim 10mg Injection with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CladribineOfatumumab
Severe
How does the drug interact with Cladrim 10mg Injection:
Combining Cladrim 10mg Injection with Ofatumumab can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Cladrim 10mg Injection and Ofatumumab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CladribineChloramphenicol
Severe
How does the drug interact with Cladrim 10mg Injection:
Taking Cladrim 10mg Injection together with chloramphenicol may increase the risk of infections.

How to manage the interaction:
There may be a possibility of interaction between Cladrim 10mg Injection and Chloramphenicol, but it can be taken if prescribed by a doctor. If you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination, make sure to contact your doctor right away. Do not discontinue any medications without consulting a doctor.
CladribineAtezolizumab
Severe
How does the drug interact with Cladrim 10mg Injection:
The combined use of Atezolizumab with Cladrim 10mg Injection can increase the risk of side effects.

How to manage the interaction:
Co-administration of Atezolizumab with Cladrim 10mg Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, or pain while urinating, contact a doctor right away. Do not stop using any medications without talking to a doctor.
CladribinePrednisolone
Severe
How does the drug interact with Cladrim 10mg Injection:
Co-administration of Cladrim 10mg Injection with Prednisolone may increase the risk of serious infections.

How to manage the interaction:
Although taking Cladrim 10mg Injection with Prednisolone together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in the coughing fluid, weight loss, red or irritated skin, body sores, or discomfort or burning while urinating. Do not stop using any medications without a doctor's advice.
CladribineDocetaxel
Severe
How does the drug interact with Cladrim 10mg Injection:
The combined use of Cladrim 10mg Injection with docetaxel can increase the risk of serious infections.

How to manage the interaction:
Taking Docetaxel with Cladrim 10mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CladribineProcarbazine
Severe
How does the drug interact with Cladrim 10mg Injection:
Combining Cladrim 10mg Injection with Procarbazine can increase the risk and severity of serious infections.

How to manage the interaction:
Although there is a possible interaction between Cladrim 10mg Injection and Procarbazine, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CladribinePemetrexed
Severe
How does the drug interact with Cladrim 10mg Injection:
Taking Cladrim 10mg Injection with Pemetrexed can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Cladrim 10mg Injection and Pemetrexed together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CladribineRituximab
Severe
How does the drug interact with Cladrim 10mg Injection:
Combining Rituximab with Cladrim 10mg Injection can increase the risk of infections.

How to manage the interaction:
Co-administration of Cladrim 10mg Injection with Rituximab can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience fever, chills, loose stools, sore throat, muscle aches, difficulty breathing, and pain or burning sensation while urinating. Do not stop using any medications without talking to a doctor.
CladribineFlucytosine
Severe
How does the drug interact with Cladrim 10mg Injection:
Taking Cladrim 10mg Injection with Flucytosine can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Flucytosine and Cladrim 10mg Injection together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, diarrhea, soreness, muscle aches, or difficulty breathing, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

Regular blood tests are recommended while receiving CLADRIM 10MG INJECTION to monitor any signs of anemia, neutropenia and thrombocytopenia.

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while receiving the medication, as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Have a query?

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