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  3. CLARIMIN 500MG INJECTION

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
48 Hrs returnable
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

ANTI- BACTERIALS

Country of origin

INDIA

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - CLA0145

Author Details

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FAQs

CLARIMIN 500MG INJECTION kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival.

Using CLARIMIN 500MG INJECTION together with statins (medicines used to lower cholesterol levels) is not advisable. Please notify your doctor if you must take these medications. Your doctor may advise you to maintain a time gap between these two medications.

CLARIMIN 500MG INJECTION can cause Clostridium difficile-associated diarrhoea (CDAD). If you have diarrhoea that is watery or bloody, inform your doctor. Do not use anti-diarrhoea medicine unless your doctor tells you to.

You should avoid taking CLARIMIN 500MG INJECTION if you have liver or kidney dysfunction, heart rhythm disorder (arrhythmia) or QT prolongation, electrolyte imbalance (low potassium or magnesium level), or muscle problems (myasthenia gravis). Inform your doctor if you have these conditions before taking CLARIMIN 500MG INJECTION.

CLARIMIN 500MG INJECTION should not be taken with any ergot derivates such as ergotamine or dihydroergotamine used to treat migraine. Consult your doctor if you have any concerns.

Prolonged use of CLARIMIN 500MG INJECTION can result in a yeast infection or oral thrush. Look out for symptoms like white patches in the mouth or changes in vaginal discharge.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is advisable to avoid or limit alcohol intake.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is not known if CLARIMIN 500MG INJECTION passes into breastmilk. Please consult your doctor.

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Driving

Caution

CLARIMIN 500MG INJECTION may cause dizziness, confusion, and loss of balance. Therefore avoid driving or operating machinery if you experience any of these symptoms.

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Liver

Caution

Caution is advised. If you have/had liver problems, your doctor may need to monitor your liver function or discontinue treatment.

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Kidney

Caution

Consult your doctor if you have kidney problems, as your doctor may need to adjust the dose.

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Children

Caution

CLARIMIN 500MG INJECTION is not recommended for children as safety and effectiveness have not been established.

About CLARIMIN 500MG INJECTION

CLARIMIN 500MG INJECTION belongs to the group of medicines known as macrolide antibiotics used to treat infections caused by bacteria such as bronchitis, pneumonia, throat, sinus, skin and soft tissue infections. It is prescribed for treating severe infections or when oral therapy is ineffective. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiply very quickly.

CLARIMIN 500MG INJECTION contains 'Clarithromycin', which works by killing the bacteria that cause the infection by preventing the synthesis of essential proteins necessary for the survival of the bacteria. Thereby, it effectively treats bacterial infections.

CLARIMIN 500MG INJECTION will be administered by a healthcare professional; do not self-administer. You may experience injection site phlebitis (redness, swelling, and pain), headache, nausea (feeling sick) or vomiting (being sick), stomach cramps or tummy pain, and diarrhoea. Most of these side effects of CLARIMIN 500MG INJECTION do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby or if you are breastfeeding; your doctor will prescribe CLARIMIN 500MG INJECTION only if the benefits outweigh the risk. Let your doctor know if you have/had liver problems; your doctor may need to monitor your liver function. CLARIMIN 500MG INJECTION may cause dizziness, confusion, and loss of balance. If you experience these, you should not drive or operate machinery. Let your doctor know about your medical condition and the medications you are taking to avoid any interactions.

Uses of CLARIMIN 500MG INJECTION

Bacterial infections

Medicinal Benefits Mweb

Medicinal Benefits

CLARIMIN 500MG INJECTION belongs to the group of medicines known as macrolide antibiotics used to treat infections caused by bacteria such as lower respiratory tract infections (acute and chronic bronchitis and pneumonia), upper respiratory tract infections (sinusitis and pharyngitis), and skin & soft tissue infections [folliculitis (inflammation of hair follicles), erysipelas (large raised red patches on the skin), cellulitis (bacterial skin infection)]. CLARIMIN 500MG INJECTION works by preventing the production of proteins required by the bacteria for its survival. Thereby killing the bacteria and treating infections. CLARIMIN 500MG INJECTION is prescribed for treating severe infections or when oral therapy is ineffective. 

Directions for Use

CLARIMIN 500MG INJECTION will be administered by a qualified healthcare professional. Kindly do not self-administer.

Side Effects of CLARIMIN 500MG INJECTION

  • Inflammation, pain or tenderness at the site of injection
  • Nausea
  • Vomiting
  • Increased sweating
  • Stomach pain
  • Diarrhoea
  • Headache

Drug Warnings

Do not take CLARIMIN 500MG INJECTION if you are allergic or hypersensitive to clarithromycin, any of the ingredients in CLARIMIN 500MG INJECTION, any other macrolide antibiotic, or ketolide (macrolide derivatives). Consult your doctor if you are pregnant or breastfeeding. Inform your doctor if you have/had hypokalemia (abnormally low levels of potassium in the blood), hypomagnesemia (abnormally low levels of magnesium in the blood), severe kidney or liver problems, heart rhythm disorders, heart problems, or are prone to fungal infections (e.g. thrush).

Drug-Drug Interactions

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ClarithromycinTerfenadine
Critical
Critical

Drug-Drug Interactions

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ClarithromycinTerfenadine
Critical
How does the drug interact with Clarimin 500mg Injection:
When Terfenadine is taken with Clarimin 500mg Injection, the amount of Terfenadine in the blood can go up.

How to manage the interaction:
Co-administration of Clarimin 500mg Injection and Terfenadine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Clarimin 500mg Injection:
When Quinidine is taken with Clarimin 500mg Injection, can increase the blood levels and effects of Quinidine. This may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Clarimin 500mg Injection and Quinidine can lead to an interaction, it can be taken if advised by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats. However, if you experience any symptoms like headache, confusion, vomiting, diarrhea, ringing in the ears, hearing loss, blurred or double vision, or sensitivity to light, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Clarimin 500mg Injection:
Using Lurasidone together with Clarimin 500mg Injection may result in significantly higher Lurasidone blood levels. This may increase the possibility of side effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurasidone and Clarimin 500mg Injection may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Clarimin 500mg Injection:
When Naloxegol is taken with Clarimin 500mg Injection, the amount of Naloxegol in the blood can go up.

How to manage the interaction:
Co-administration of Clarimin 500mg Injection and Naloxegol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Clarimin 500mg Injection:
When Dronedarone is taken with Clarimin 500mg Injection, can increase the blood levels of dronedarone and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Clarimin 500mg Injection with Dronedarone can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Clarimin 500mg Injection:
Co-administration of Bepridil with Clarimin 500mg Injection may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Clarimin 500mg Injection with Bepridil is not recommended as it can result in an interaction, it should be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clarimin 500mg Injection:
Taking Clarimin 500mg Injection with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Clarimin 500mg Injection and Ziprasidone can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Clarimin 500mg Injection:
Taking Clarimin 500mg Injection with Lovastatin can increase the risk of muscle problems.

How to manage the interaction:
Co-administration of Clarimin 500mg Injection and Lovastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinErgotamine
Critical
How does the drug interact with Clarimin 500mg Injection:
When Ergotamine is taken with Clarimin 500mg Injection, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Clarimin 500mg Injection with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clarimin 500mg Injection:
The combination of Alprazolam and Clarimin 500mg Injection may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Alprazolam and Clarimin 500mg Injection, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CLARITHROMYCIN-500MGOther bacterial intestinal infections
Severe
CLARITHROMYCIN-500MGToxic liver disease
Moderate

Drug-Diseases Interactions

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CLARITHROMYCIN-500MGOther bacterial intestinal infections
Severe
How does the disease interact with Clarimin 500mg Injection:
Almost all antibacterial medications have been associated with cases of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent those involved.

How to manage the interaction:
Anti-bacterial medicines may cause Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis. Therapy should be administered with caution in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile is advised.
CLARITHROMYCIN-500MGToxic liver disease
Moderate
How does the disease interact with Clarimin 500mg Injection:
Patients on Clarimin 500mg Injection have been reported to experience hepatic dysfunction, including elevated liver enzymes, cholestatic and/or hepatocellular hepatitis, with or without jaundice. Using this medication to patients with hepatic impairment requires caution and close monitoring. If hepatitis signs and symptoms appear, treatment must be stopped.

How to manage the interaction:
Caution and monitoring is advised if Clarimin 500mg Injection is used in patients with liver impairment. Treatment must be discontinued immediately if signs and symptoms of hepatitis such as anorexia, jaundice, dark urine, pruritus, or tender abdomen occur. The use of Clarimin 500mg Injection is contraindicated in patients with a history of cholestatic jaundice or liver impairment associated with the prior use of Clarimin 500mg Injection.
CLARITHROMYCIN-500MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Clarimin 500mg Injection:
The kidney and liver are the organs that eliminate of Clarimin 500mg Injection the most. In individuals with severe renal impairment (CrCl 30 mL/min), a lower dose or longer dosing intervals are advised. Patients with mild to moderate renal impairment often do not require dosage modifications, while medication accumulation may happen if there is concurrent liver illness. It is suggested to monitor.

How to manage the interaction:
Dose adjustment may be needed in patients with severe kidney impairment. Monitoring is advised in patients with mild to moderate kidney impairment.
CLARITHROMYCIN-500MGMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Clarimin 500mg Injection:
Myasthenia gravis symptoms have been observed to worsen and new myasthenic syndrome symptoms appear when macrolide antibiotics are used, according to reports. In patients who have a history of myasthenia gravis, therapy with these medicines should be used with caution.

How to manage the interaction:
Therapy should be administered cautiously in patients with a history of myasthenia gravis as the use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis.
CLARITHROMYCIN-500MGAbnormal results of function studies
Moderate
How does the disease interact with Clarimin 500mg Injection:
Macrolides have been associated with an increase in the QT interval and occasional cases of arrhythmia. Patients with known QT interval prolongation, ventricular cardiac arrhythmia, including torsades de pointes, patients with proarrhythmic conditions like untreated hypokalemia or hypomagnesemia, clinically significant bradycardia, or patients taking other drugs that prolong the QT interval should avoid taking Clarimin 500mg Injection and erythromycin.

How to manage the interaction:
Clarimin 500mg Injection should be avoided in patients with known prolongation of the QT interval, abnormal heart rhythm, uncorrected low potassium or low magnesium, clinically significant slow heart rate, or receiving other drugs that prolong the QT interval.

Drug-Drug Interactions Checker List

  • ERGOTAMINE
  • DIHYDROERGOTAMINE
  • TERFENADINE
  • ASTEMIZOLE
  • CISAPRIDE
  • DOMPERIDONE
  • PIMOZIDE
  • LOVASTATIN
  • SIMVASTATIN
  • LOMITAPIDE
  • ATORVASTATIN
  • MIDAZOLAM
  • COLCHICINE
  • TICAGRELOR
  • RANOLAZINE
  • ALPRAZOLAM
  • BUDESONIDE/FORMOTEROL

Habit Forming

No

Special Advise

  • CLARIMIN 500MG INJECTION might affect blood and liver tests. Inform the person doing the tests that you are taking CLARIMIN 500MG INJECTION.

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of CLARIMIN 500MG INJECTION to restore healthy bacteria in the intestine that may have been killed due to the use of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole grains like whole-grain bread, and brown rice, should be included in the diet.
  • Avoid intake of alcoholic beverages with CLARIMIN 500MG INJECTION as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid CLARIMIN 500MG INJECTION in fighting off infections.

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