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  3. Cloneon Injection 1 ml

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Composition :

CLONIDINE-150MCG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTI- HYPERTENSIVES

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - CLO0138

Author Details

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FAQs

Disclaimer

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Alcohol

Caution

You are recommended to avoid alcohol consumption while on treatment with Cloneon Injection 1 ml to avoid unpleasant side-effects.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe Cloneon Injection 1 ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Cloneon Injection 1 ml. Please consult your doctor if you have any concerns regarding this.

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Driving

Caution

Cloneon Injection 1 ml may cause dizziness and sleepiness. Drive and operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Cloneon Injection 1 ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Cloneon Injection 1 ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Cloneon Injection 1 ml is not recommended for children as safety and effectiveness have not been established.

About Cloneon Injection 1 ml

Cloneon Injection 1 ml belongs to a class of medicines called antihypertensives used to treat hypertension (high blood pressure). Besides this, Cloneon Injection 1 ml is also used alone or in combination with opiate medicines for the treatment of severe pain in cancer patients which is not sufficiently relieved by opioid analgesics alone. 
 
Cloneon Injection 1 ml relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke. Also, Cloneon Injection 1 ml prevents the transmission of pain signals to the brain, thereby providing relief from pain.
 
In some cases, Cloneon Injection 1 ml may cause dry mouth, headache, dizziness, nausea, postural hypotension and low blood pressure. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Cloneon Injection 1 ml is not recommended for obstetrical (related to childbirth), post-partum, or peri-operative pain management. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Cloneon Injection 1 ml. Cloneon Injection 1 ml may cause dizziness, so drive only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Cloneon Injection 1 ml

Hypertension (high blood pressure), Pain relief

Medicinal Benefits Mweb

Medicinal Benefits

Cloneon Injection 1 ml is used to treat hypertension (high blood pressure). Cloneon Injection 1 ml relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke. Cloneon Injection 1 ml is also used alone or in combination with opiate medicines for the treatment of severe pain in cancer patients which is not sufficiently relieved by opioid analgesics alone. Cloneon Injection 1 ml prevents the transmission of pain signals to the brain, thereby providing relief from pain.

Directions for Use

Cloneon Injection 1 ml will be administered by a healthcare professional; do not self-administer.

Side Effects of Cloneon Injection 1 ml

  • Dry mouth
  • Headache
  • Dizziness
  • Postural hypotension
  • Hypotension (low blood pressure)
  • Nausea

Drug Warnings

Do not take Cloneon Injection 1 ml if you are allergic to any of its contents. Inform your doctor if you have/had bleeding problems, circulation problems, stroke, depression, diabetes, nervous problems, constipation, phaeochromocytoma (tumour of adrenal glands), heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Cloneon Injection 1 ml is not recommended for children as safety and effectiveness have not been established. Cloneon Injection 1 ml may cause dizziness, so avoid driving or operating machinery unless you are alert.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Metoprolol Succinate together may lower the blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Metoprolol Succinate, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Doxepin may increase the risk and severity of increased blood pressure.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Doxepin, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact your doctor. Do not stop using any medications without consulting your doctor.
ClonidineSodium oxybate
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml can enhance the sedative effects of Sodium oxybate on the central nervous system.

How to manage the interaction:
Co-administration of Cloneon Injection 1 ml with Sodium oxybate can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and be aware of any changes. If you notice any of these signs - feeling tired, dizzy, lightheaded, confused, sad, having low blood pressure, or difficulty breathing - make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
ClonidineNadolol
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Nadolol may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Nadolol, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Carvedilol can increase the risk of irregular heart rhythms or low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Carvedilol, you can take these medicines if prescribed by a doctor. However, if you experience palpitations, chest discomfort, dizziness, or shortness of breath, contact a doctor. Do not discontinue the medication without consulting a doctor.
ClonidineEsketamine
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml with Esketamine can increase the risk of side effects.

How to manage the interaction:
Taking Cloneon Injection 1 ml with Esketamine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having trouble with feeling tired, restless, confused, or finding it hard to focus, it's important to reach out to a doctor right away. They may be able to recommend other options that won't cause these issues. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Labetalol may increase the risk of side effects like lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Labetalol, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Cloneon Injection 1 ml:
The combination of esmolol and Cloneon Injection 1 ml may reduce your blood pressure and lower your heart rate.

How to manage the interaction:
Although there is a possible interaction between Esmolol and Cloneon Injection 1 ml, you can take these medicines together if prescribed by a doctor. However, if you may experience a sluggish heartbeat, headaches, dizziness, or the sensation of passing out, consult the doctor. Do not discontinue any medications without consulting the doctor.
ClonidineProtriptyline
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Protriptyline may increase the risk and severity of high blood pressure.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Protriptyline, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact your doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Atenolol may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Atenolol, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, contact a doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CLONIDINE-150MCGAbnormalities of heart beat
Moderate
CLONIDINE-150MCGDepressive episode
Moderate

Drug-Diseases Interactions

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CLONIDINE-150MCGAbnormalities of heart beat
Moderate
How does the disease interact with Cloneon Injection 1 ml:
Alpha-2 adrenoreceptor agonists in the central nervous system decrease sympathetic outflow. Atrioventricular block and sinus bradycardia may develop or worsen as a result of the reduced heart rate. Patients with conduction problems such sinus node dysfunction or AV nodal illness should use caution while receiving therapy with central alpha-2 adrenoreceptor agonists.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with heart problems.
CLONIDINE-150MCGDepressive episode
Moderate
How does the disease interact with Cloneon Injection 1 ml:
In patients who have a history of depression, central alpha-2 adrenoreceptor agonists should be administered with caution since they can occasionally result in mental depression.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with a history of depression.
CLONIDINE-150MCGHypotension
Moderate
How does the disease interact with Cloneon Injection 1 ml:
As a result of decreased sympathetic outflow from the central nervous system caused by central alpha-2 adrenoreceptor agonists, blood pressure, peripheral and renovascular resistance, and heart rate all decreased. Patients who have hypotension or illnesses that could be made worse by low blood pressure and perfusion, such as coronary insufficiency, peripheral vascular disease (like Raynaud's syndrome), cerebrovascular disease, or a recent myocardial infarction, should use these medications with caution.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with hypotension (low blood pressure) or conditions that may worsen by decreased blood pressure, such as coronary insufficiency (inadequate blood circulation through coronary arteries), peripheral vascular disease (e.g., Raynaud's syndrome), cerebrovascular disease (conditions that affect blood flow to your brain), or recent myocardial infarction (heart attack).
CLONIDINE-150MCGHypotension
Moderate
How does the disease interact with Cloneon Injection 1 ml:
As a result of decreased sympathetic outflow from the central nervous system caused by central alpha-2 adrenoreceptor agonists, blood pressure, peripheral and renovascular resistance, and heart rate all decreased. Patients who have hypotension or illnesses that could be made worse by low blood pressure and perfusion, such as coronary insufficiency, peripheral vascular disease (like Raynaud's syndrome), cerebrovascular disease, or a recent myocardial infarction, should use these medications with caution.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with hypotension (low blood pressure) or conditions that may worsen by decreased blood pressure, such as coronary insufficiency (inadequate blood circulation through coronary arteries), peripheral vascular disease (e.g., Raynaud's syndrome), cerebrovascular disease (conditions that affect blood flow to your brain), or recent myocardial infarction (heart attack).
CLONIDINE-150MCGHypotension
Moderate
How does the disease interact with Cloneon Injection 1 ml:
As a result of decreased sympathetic outflow from the central nervous system caused by central alpha-2 adrenoreceptor agonists, blood pressure, peripheral and renovascular resistance, and heart rate all decreased. Patients who have hypotension or illnesses that could be made worse by low blood pressure and perfusion, such as coronary insufficiency, peripheral vascular disease (like Raynaud's syndrome), cerebrovascular disease, or a recent myocardial infarction, should use these medications with caution.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with hypotension (low blood pressure) or conditions that may worsen by decreased blood pressure, such as coronary insufficiency (inadequate blood circulation through coronary arteries), peripheral vascular disease (e.g., Raynaud's syndrome), cerebrovascular disease (conditions that affect blood flow to your brain), or recent myocardial infarction (heart attack).
CLONIDINE-150MCGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Cloneon Injection 1 ml:
The kidney is principally responsible for the unaltered elimination of Cloneon Injection 1 ml. Patients may benefit from a lower initial dose since the serum concentrations and half-life of Cloneon Injection 1 ml may be enhanced in those with impaired renal function. The degree of renal impairment should be taken into consideration while modifying the dosage. There is no need to provide more Cloneon Injection 1 ml after dialysis since only a little quantity of Cloneon Injection 1 ml is eliminated during regular hemodialysis.

How to manage the interaction:
Dose adjustments may be required based on the degree of kidney impairment. Therefore, inform your doctor if you have any kidney problems before taking Cloneon Injection 1 ml.
CLONIDINE-150MCGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Cloneon Injection 1 ml:
The kidney is principally responsible for the unaltered elimination of Cloneon Injection 1 ml. Patients may benefit from a lower initial dose since the serum concentrations and half-life of Cloneon Injection 1 ml may be enhanced in those with impaired renal function. The degree of renal impairment should be taken into consideration while modifying the dosage. There is no need to provide more Cloneon Injection 1 ml after dialysis since only a little quantity of Cloneon Injection 1 ml is eliminated during regular hemodialysis.

How to manage the interaction:
Dose adjustments may be required based on the degree of kidney impairment. Therefore, inform your doctor if you have any kidney problems before taking Cloneon Injection 1 ml.

Drug-Drug Interactions Checker List

  • DIGITALIS
  • FLUPHENAZINE

Habit Forming

No

Special Advise

  • Regularly monitor blood pressure levels to prevent hypotension (low blood pressure).
  • Get up slowly while rising from lying or sitting position as Cloneon Injection 1 ml may cause dizziness.
  • Your doctor may advise you to get regular kidney function tests and potassium levels tested whilst on treatment with Cloneon Injection 1 ml. 

Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet while taking Cloneon Injection 1 ml. 
  • Regular exercise is also recommended to complement treatment with Cloneon Injection 1 ml.
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Manage stress with meditation, yoga, and massage.

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