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Composition :
CLOMIPRAMINE-25MG
Manufacturer/Marketer :
Sigmund Promedica
Consume Type :
Oral
Expires on or after :
Return Policy :
Not Returnable
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Product Substitutes
Drug-Drug Interactions
clomipheneOspemifene
Critical
clomipheneFluoroestradiol (18f)
Severe
Drug-Drug Interactions
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clomipheneOspemifene
Critical
How does the drug interact with Clora 25 mg Tablet:
Co-administration of Clomifene with Ospemifene can increase the seriousness of side effects.
How to manage the interaction:
Taking Clora 25 mg Tablet with Ospemifene is not recommended, please consult a doctor before taking it.
Co-administration of Clomifene with Ospemifene can increase the seriousness of side effects.
How to manage the interaction:
Taking Clora 25 mg Tablet with Ospemifene is not recommended, please consult a doctor before taking it.
clomipheneFluoroestradiol (18f)
Severe
How does the drug interact with Clora 25 mg Tablet:
Co-administration of Fluoroestradiol F 18 together with Clora 25 mg Tablet may reduce the action of Fluoroestradiol F 18.
How to manage the interaction:
Taking Clora 25 mg Tablet with Fluoroestradiol (18f) together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
Co-administration of Fluoroestradiol F 18 together with Clora 25 mg Tablet may reduce the action of Fluoroestradiol F 18.
How to manage the interaction:
Taking Clora 25 mg Tablet with Fluoroestradiol (18f) together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
clomipheneBexarotene
Severe
How does the drug interact with Clora 25 mg Tablet:
Co-administration of Clora 25 mg Tablet with Bexarotene may increase the risk of pancreatitis, or inflammation of the pancreas.
How to manage the interaction:
Although there is an interaction, Clora 25 mg Tablet can be taken with Bexarotene if prescribed by the doctor. Consult the prescriber if you experience symptoms of pancreatitis such as persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back. Do not discontinue the medication without consulting a doctor.
Co-administration of Clora 25 mg Tablet with Bexarotene may increase the risk of pancreatitis, or inflammation of the pancreas.
How to manage the interaction:
Although there is an interaction, Clora 25 mg Tablet can be taken with Bexarotene if prescribed by the doctor. Consult the prescriber if you experience symptoms of pancreatitis such as persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back. Do not discontinue the medication without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
CLOMIPRAMINE-25MGOther abnormal uterine and vaginal bleeding
Severe
CLOMIPRAMINE-25MGHepatic failure, not elsewhere classified
Severe
Drug-Diseases Interactions
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CLOMIPRAMINE-25MGOther abnormal uterine and vaginal bleeding
Severe
How does the disease interact with Clora 25 mg Tablet:
Abnormal uterine bleeding: In patients who are not diagnosed with abnormal genital bleeding, Clora 25 mg Tablet is contraindicated. Evaluate the patients for the presence of neoplastic lesions.
How to manage the interaction:
The use of Clora 25 mg Tablet is contraindicated in patients with undiagnosed, abnormal genital bleeding.
Abnormal uterine bleeding: In patients who are not diagnosed with abnormal genital bleeding, Clora 25 mg Tablet is contraindicated. Evaluate the patients for the presence of neoplastic lesions.
How to manage the interaction:
The use of Clora 25 mg Tablet is contraindicated in patients with undiagnosed, abnormal genital bleeding.
CLOMIPRAMINE-25MGHepatic failure, not elsewhere classified
Severe
How does the disease interact with Clora 25 mg Tablet:
Hepatic dysfunction: Clora 25 mg Tablet is contraindicated for patients who have liver failure or a past history of hepatic dysfunction. The Clora 25 mg Tablet is primarily metabolized in the liver and enters into enterohepatic circulation. Thus, there will be increase in serum concentration and half-life of Clora 25 mg Tablet.
How to manage the interaction:
The use of Clora 25 mg Tablet is contraindicated in patients with liver disease or history of hepatic dysfunction.
Hepatic dysfunction: Clora 25 mg Tablet is contraindicated for patients who have liver failure or a past history of hepatic dysfunction. The Clora 25 mg Tablet is primarily metabolized in the liver and enters into enterohepatic circulation. Thus, there will be increase in serum concentration and half-life of Clora 25 mg Tablet.
How to manage the interaction:
The use of Clora 25 mg Tablet is contraindicated in patients with liver disease or history of hepatic dysfunction.
CLOMIPRAMINE-25MGDisorders of endocrine glands in diseases classified elsewhere
Severe
How does the disease interact with Clora 25 mg Tablet:
Pituitary activity: Clora 25 mg Tablet is contraindicated for patients who have uncontrolled thyroid or adrenal dysfunction, or who have an organic intracranial lesion such as a pituitary tumour. Clora 25 mg Tablet interacts with oestrogen receptors in several tissues, including the pituitary, causing a rise in pituitary gonadotropin secretion.
How to manage the interaction:
Clora 25 mg Tablet is contraindicated in patients with uncontrolled thyroid, adrenal dysfunction or pituitary tumour.
Pituitary activity: Clora 25 mg Tablet is contraindicated for patients who have uncontrolled thyroid or adrenal dysfunction, or who have an organic intracranial lesion such as a pituitary tumour. Clora 25 mg Tablet interacts with oestrogen receptors in several tissues, including the pituitary, causing a rise in pituitary gonadotropin secretion.
How to manage the interaction:
Clora 25 mg Tablet is contraindicated in patients with uncontrolled thyroid, adrenal dysfunction or pituitary tumour.
CLOMIPRAMINE-25MGOther disorders of adrenal gland
Severe
How does the disease interact with Clora 25 mg Tablet:
Uncontrolled adrenal dysfunction : Clora 25 mg Tablet is contraindicated in patients with uncontrolled adrenal function. Adrenal dysfunction can make pregnancy difficult. Clora 25 mg Tablet therapy may cause changes in steroid production and/or fluid balance.
How to manage the interaction:
The use of Clora 25 mg Tablet is contraindicated in patients with uncontrolled adrenal function.
Uncontrolled adrenal dysfunction : Clora 25 mg Tablet is contraindicated in patients with uncontrolled adrenal function. Adrenal dysfunction can make pregnancy difficult. Clora 25 mg Tablet therapy may cause changes in steroid production and/or fluid balance.
How to manage the interaction:
The use of Clora 25 mg Tablet is contraindicated in patients with uncontrolled adrenal function.
CLOMIPRAMINE-25MGDisorders of lipoprotein metabolism and other lipidaemias
Moderate
How does the disease interact with Clora 25 mg Tablet:
Hyperlipidemia: Some patients who are on Clora 25 mg Tablet therapy have reported hypertriglyceridemia. Preexisting hyperlipidemia or a family history of hyperlipidemia, Higher doses of Clora 25 mg Tablet for a long period are related to an increased risk of hypertriglyceridemia. In this conditions, Monitor plasma triglycerides regular basis and also at base line before initiating the therapy with Clora 25 mg Tablet.
How to manage the interaction:
Hypertriglyceridemia may occur during Clora 25 mg Tablet therapy, especially in patients with a family history of hyperlipidemia and use of higher than the recommended dose and/or longer duration of treatment. Periodic monitoring of plasma triglycerides is recommended in patients with preexisting or family history of hyperlipidemia. Pretreatment screening of triglyceride levels is advised in patients initiating Clora 25 mg Tablet therapy.
Hyperlipidemia: Some patients who are on Clora 25 mg Tablet therapy have reported hypertriglyceridemia. Preexisting hyperlipidemia or a family history of hyperlipidemia, Higher doses of Clora 25 mg Tablet for a long period are related to an increased risk of hypertriglyceridemia. In this conditions, Monitor plasma triglycerides regular basis and also at base line before initiating the therapy with Clora 25 mg Tablet.
How to manage the interaction:
Hypertriglyceridemia may occur during Clora 25 mg Tablet therapy, especially in patients with a family history of hyperlipidemia and use of higher than the recommended dose and/or longer duration of treatment. Periodic monitoring of plasma triglycerides is recommended in patients with preexisting or family history of hyperlipidemia. Pretreatment screening of triglyceride levels is advised in patients initiating Clora 25 mg Tablet therapy.
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