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  3. Clorpam Injections 1's

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rxMedicinePrescription drug

Composition :

CLONAZEPAM-1MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICONVULSANT

Country of origin

INDIA

Manufacturer/Marketer address

16Th Floor, Godrej Bkc, Plot C, G Block, Bandra-Kurla Complex, Bandra (East), Mumbai 400 051, India.
Other Info - CLO0872

Author Details

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FAQs

Clorpam Injections works by increasing levels of the calming chemical known as gamma-aminobutyric acid (GABA) in the brain, which helps to stop status epilepticus (seizures attacks).

Caffeine is a stimulant that may reduce the calming effects of Clorpam Injections. So, it is advisable to avoid the intake of caffeinated beverages like coffee, tea, cola, or chocolate that contain caffeine.

Elderly patients (over 65 years) are more likely to have confusion and sleepiness or age-related health issues, which may require caution and an adjustment in the dose. Consult your doctor if you have any concerns regarding this.

If Clorpam Injections is stopped suddenly, it may cause withdrawal symptoms such as agitation, tremor, sweating, anxiety, headache, sleep disturbances, irritability, and confusion. Your doctor may lower the dose of Clorpam Injections gradually to prevent withdrawal symptoms.

Clorpam Injections should not be used in individuals in a coma or with a history of drug, alcohol, or medication abuse.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

You are recommended not to consume alcohol while using Clorpam Injections to avoid unpleasant side effects like drowsiness, dizziness, or sleepiness. It may also lead to a life-threatening condition like coma if taken with excessive alcohol.

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Pregnancy

Caution

Clorpam Injections should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Clorpam Injections.

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Breast Feeding

Unsafe

Clorpam Injections may pass into breastmilk. Avoid breastfeeding while on treatment with Clorpam Injections.

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Driving

Unsafe

Clorpam Injections may cause dizziness. Avoid driving or operating heavy machinery.

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Liver

Caution

Inform your doctor if you have a history of liver diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing it.

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Kidney

Caution

Inform your doctor if you have a history of kidney diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing it.

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Children

Safe if prescribed

Special attention must be taken while using Clorpam Injections in children.

About Clorpam Injections

Clorpam Injections belongs to a group of medications called benzodiazepines, primarily used to treat status epilepticus. Status epilepticus is defined as a seizure lasting more than 5 minutes or experiencing more than one seizure within 5 minutes without returning to a normal level of consciousness between episodes.

Clorpam Injections contains clonazepam, which works by increasing levels of the calming chemical known as gamma-aminobutyric acid (GABA) in the brain, which helps to stop status epilepticus (seizures attacks).

Clorpam Injections will be administered by a healthcare professional; do not self-administer. You may experience pain, itching, swelling or redness around the site of injection, daytime drowsiness, disturbed sleep, light-headedness, or dizziness. Most of these side effects of Clorpam Injections do not require medical attention and gradually resolve over time. However, please contact your doctor if the side effects are persistent.

Do not take Clorpam Injections if you have sensitivity to clonazepam or any of the excipients present in it. Patients having a history of depression and/or suicidal tendencies should be closely monitored. If you are pregnant or breastfeeding, please tell your doctor so that your doctor will weigh the benefits and any potential risks before prescribing it to you. Clorpam Injections is a habit-forming drug; therefore, your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Uses of Clorpam Injections

Status epilepticus

Medicinal Benefits Mweb

Medicinal Benefits

Clorpam Injections contains clonazepam, which works by increasing levels of the calming chemical known as gamma-aminobutyric acid (GABA) in the brain, which helps to stop status epilepticus (seizures attacks). Besides this, it may decrease the feeling of nervousness, stress, and anxiety, which leads to a state of calmness and relaxation.

Directions for Use

Clorpam Injections will be administered by a qualified healthcare professional. Kindly do not self-administer.

Side Effects of Clorpam Injections

  • Pain, itching, swelling or redness around the site of injection
  • Disturbed sleep (such as vivid dreams)
  • Feeling sleepy (drowsy) in the daytime
  • Feeling light-headed,
  • Dizziness
  • Muscle weakness
  • Nystagmus (an involuntary eye movement)

Drug Warnings

Do not take Clorpam Injections if you are allergic to any of its components; if you have lung disease, muscle weakness (myasthenia gravis), sleeping disorders or difficulty sleeping (sleep apnoea), severe respiratory insufficiency, depression, suicidal tendencies, severe liver or hepatic disease, or a problem with alcohol or other prescription drugs. Inform your doctor if you have weakness, pulmonary insufficiency, kidney or liver problems. If you are pregnant or breastfeeding, please tell your doctor so that your doctor will weigh the benefits and any potential risks before prescribing it to you. Clorpam Injections is a habit-forming drug; therefore, your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Clorpam Injections:
Taking Clorpam Injections with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Clorpam Injections and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clorpam Injections:
When Buprenorphine is used with Clorpam Injections, it may lead to significant adverse effects such as respiratory difficulties.

How to manage the interaction:
Co-administration of Buprenorphine alongside Clorpam Injections can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you know how these drugs affect you. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clorpam Injections:
Co-administration of Tapentadol together with Clorpam Injections can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Clorpam Injections with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clorpam Injections:
When Clorpam Injections and Ketamine are taken together, may increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Ketamine and Clorpam Injections, but it can be taken if prescribed by a doctor. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Clorpam Injections:
Co-administration of Butorphanol with Clorpam Injections can increase the risk of side effects.

How to manage the interaction:
Although taking Clorpam Injections and Butorphanol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamCodeine
Severe
How does the drug interact with Clorpam Injections:
Co-administration of Clorpam Injections with Codeine may cause serious side effects like respiratory depression.

How to manage the interaction:
Consult a doctor if you are taking Clorpam Injections with Codeine. Until you know how the medicines affect you, avoid driving or operating hazardous machinery as these medications may cause drowsiness, dizziness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not stop using any medications without talking to a doctor.
ClonazepamHydromorphone
Severe
How does the drug interact with Clorpam Injections:
Co-administration of Clorpam Injections with Hydromorphone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Clorpam Injections with Hydromorphone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Clorpam Injections:
Co-administration of Nalbuphine with Clorpam Injections can make the side effects worse.

How to manage the interaction:
Although there is a possible interaction between Clorpam Injections and Nalbuphine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Clorpam Injections:
Co-administration of Pentazocine with Clorpam Injections can increase the risk of side effects.

How to manage the interaction:
Taking Clorpam Injections with Pentazocine together can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamPethidine
Severe
How does the drug interact with Clorpam Injections:
Combining Meperidine with Clorpam Injections can increase the risk of side effects.

How to manage the interaction:
Taking Pethidine with Clorpam Injections together can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CLONAZEPAM-1MGGlaucoma
Severe
CLONAZEPAM-1MGMental and behavioural disorders due to multiple drug use and use of other psychoactive substances
Severe

Drug-Diseases Interactions

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CLONAZEPAM-1MGGlaucoma
Severe
How does the disease interact with Clorpam Injections:
Benzodiazepines should not be used by people who have open-angle glaucoma or acute angle-closure glaucoma. While these drugs have very rarely being associated with increased intraocular pressure, they do not have anticholinergic effect.

How to manage the interaction:
Clorpam Injections is contraindicated in patients with acute angle-closure glaucoma or untreated open-angle glaucoma.
CLONAZEPAM-1MGMental and behavioural disorders due to multiple drug use and use of other psychoactive substances
Severe
How does the disease interact with Clorpam Injections:
Benzodiazepines have the potential to cause abuse and dependency. Particularly during extended usage and/or high dosages, tolerance as well as physical and psychological dependency might form.

How to manage the interaction:
Benzodiazepines have the potential to cause dependence and abuse. If dependency is suspected, withdrawal of benzodiazepine therapy should be done by gradual dose reduction.
CLONAZEPAM-1MGAbnormalities of breathing
Severe
How does the disease interact with Clorpam Injections:
When administered in large doses and/or by intravenous administration, benzodiazepines have the potential to cause respiratory depression and apnea. However, some individuals, such as the elderly, the very ill, those who are impaired or taking other CNS depressants, as well as those who have a limited ventilatory reserve, chronic pulmonary insufficiency, or other respiratory diseases, may be susceptible even at regularly prescribed dosages. In these individuals, benzodiazepine therapy should be used with caution.

How to manage the interaction:
When given in high dosages and/or by intravenous administration, benzodiazepines may cause respiratory depression and apnea. Therapy with benzodiazepines should be administered cautiously in patients including elderly, debilitated or severely ill patients, those receiving other CNS depressants, those with limited ventilatory reserve, chronic pulmonary insufficiency or other respiratory disorders.
CLONAZEPAM-1MGEpilepsy
Severe
How does the disease interact with Clorpam Injections:
The use of benzodiazepines for patients with seizure disorders may increase the frequency of generalised tonic-clonic seizures (grand mal) or accelerate the onset of them. The dosage of an appropriate anticonvulsant drug may need to be raised. Particularly after lengthy usage and/or high dosages, abruptly stopping benzodiazepine medication can cause seizures and other withdrawal symptoms. Patients with a history of seizures who discontinue benzodiazepine medication suddenly may experience status epilepticus.

How to manage the interaction:
Benzodiazepines in patients with seizure disorders may increase the incidence of fits. Dose adjustment or appropriate anticonvulsant medication might need to be initiated. Do not discontinue medication without first consulting with the physician.
CLONAZEPAM-1MGPoisoning by diuretics and other and unspecified drugs, medicaments and biological substances
Severe
How does the disease interact with Clorpam Injections:
Benzodiazepines in paediatric and psychiatric patients with aggressive hyperactivity problems. During benzodiazepine medication for such individuals, it is important to keep monitoring out for any indications of paradoxical stimulation.

How to manage the interaction:
Use of benzodiazepines with alcohol is not recommended. Therapy with benzodiazepines should be administered cautiously in patients who might be prone to acute alcohol intake.
CLONAZEPAM-1MGDepressive episode
Moderate
How does the disease interact with Clorpam Injections:
The central nervous system is depressed by benzodiazepines, which can also result in or aggravate mental depression as well as suicidal behaviour and ideas. Patients who were being treated for depression with some of these medications have also reported experiencing episodes of mania and hypomania. In individuals with a history of depression or other mental illnesses, the use of benzodiazepines should be provided with caution. Patients should be watched for any changes in attitude or behaviour. It could be wise to hold off on giving these people a lot of medicine.

How to manage the interaction:
Benzodiazepines may cause or exacerbate mental depression and cause suicidal behavior and ideation. Therapy with benzodiazepines should be administered cautiously in patients with a history of depression or other psychiatric disorders. Monitoring is advised in patients for any changes in mood or behavior.

Drug-Drug Interactions Checker List

  • SODIUM OXYBATE
  • PHENYTOIN
  • PHENOBARBITAL
  • CARBAMAZEPINE
  • VALPROATE
  • KETAMINE
  • ESTAZOLAM
  • NICOTINE
  • CAFFEINE
  • ALFENTANIL
  • BUPRENORPHINE
  • CODEINE
  • HYDROCODONE
  • HYDROMORPHONE
  • TIZANIDINE

Habit Forming

Yes

Special Advise

  • Consult your doctor immediately if you have any suicidal thoughts such as killing or harming yourself.
  • Patients having a history of depression and/or suicidal tendencies should be closely monitored.

Diet & Lifestyle Advise

  • Attend therapy sessions regularly.
  • Eat a healthy diet.
  • Try to stay active and exercise regularly.
  • Take ample rest. Get enough sleep.
  • Avoid smoking, caffeine, and alcohol consumption.

Have a query?