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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
48 Hrs returnable
COD available

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Whats That

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Composition :

ENOXAPARIN-40MG

Manufacturer/Marketer :

Venus Remedies Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Country of origin

India

Manufacturer/Marketer address

Sco 857, Cabin No. 10, 2nd Floor, Nac, Manimajra, Chandigarh (U.T.), 160101, India
Other Info - CLO1485

FAQs

Cloti-XA 40 mg/0.4 ml Injection 1's contains Enoxaparin, which is low molecular weight heparin or LMWH. Cloti-XA 40 mg/0.4 ml Injection 1's works by stopping existing blood clots from getting any bigger. This helps your body to break them down and prevents them from causing you harm. On the other hand, it stops new blood clots from forming in your blood.

Yes, this Cloti-XA 40 mg/0.4 ml Injection 1's is given based on your age and body weight. If you have low body weight, the chances of increased risk of bleeding are high, so mostly low doses are prescribed by your doctor. You may be monitored closely for signs of clot formation.

No, do not take this Cloti-XA 40 mg/0.4 ml Injection 1's if you have a stomach ulcer. Please inform your doctor about this condition before receiving it.

Yes, Cloti-XA 40 mg/0.4 ml Injection 1's may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, or unusual bleeding from the gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Increases in liver enzymes are the most common side effect with Cloti-XA 40 mg/0.4 ml Injection 1's. Regular lipid profile tests are recommended to avoid any additional complications.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Limit intake of alcohol as it may increase the risk of bleeding.

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Pregnancy

Caution

Cloti-XA 40 mg/0.4 ml Injection 1's is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Cloti-XA 40 mg/0.4 ml Injection 1's.

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Breast Feeding

Caution

Cloti-XA 40 mg/0.4 ml Injection 1's is not recommended for use in breastfeeding unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Cloti-XA 40 mg/0.4 ml Injection 1's.

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Driving

Safe if prescribed

It does not affect your ability to drive.

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Liver

Caution

If you have a history of liver diseases or pre-existing liver conditions, please inform your doctor before taking this Cloti-XA 40 mg/0.4 ml Injection 1's. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

If you have a history of kidney diseases or pre-existing kidney conditions, please inform your doctor before taking this Cloti-XA 40 mg/0.4 ml Injection 1's. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

It is not recommended for treatment in children under 18 years of age as safety and efficacy have not been established.

About Cloti-XA 40 mg/0.4 ml Injection 1's

Cloti-XA 40 mg/0.4 ml Injection 1's belongs to a class of medications known as blood thinners or anticoagulants. It helps to treat harmful blood clots in your blood. Furthermore, Cloti-XA 40 mg/0.4 ml Injection 1's can prevent or treat blood clots caused by a variety of medical conditions, such as unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and blood clots forming in your dialysis machine's tubes. A blood clot is a mass of blood that forms when platelets, proteins, and cells in the blood stick together. A blood clot can occur in any body part, leading to a heart attack, stroke, and organ damage (even coma or death).

Cloti-XA 40 mg/0.4 ml Injection 1's contains Enoxaparin, which is low molecular weight heparin. Cloti-XA 40 mg/0.4 ml Injection 1's works by preventing existing blood clots from growing larger, allowing your body to break them down and prevent them from harming you. On the other hand, it inhibits the formation of new blood clots in your blood.

Cloti-XA 40 mg/0.4 ml Injection 1's will be administered by a healthcare professional; do not self-administer. You may experience bleeding, increased liver enzymes, skin rash (hives, urticaria), itchy red skin, bruising or pain at the injection site, and headache as side effects of Cloti-XA 40 mg/0.4 ml Injection 1's. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, report to your doctor immediately. 

If you are known to be allergic to Cloti-XA 40 mg/0.4 ml Injection 1's or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before receiving the Cloti-XA 40 mg/0.4 ml Injection 1's. Also, disclose to your doctor if you have any pre-existing medical conditions like a stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders. And also, let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Uses of Cloti-XA 40 mg/0.4 ml Injection 1's

Treatment and prevention of blood clots

Medicinal Benefits Mweb

Medicinal Benefits

Cloti-XA 40 mg/0.4 ml Injection 1's contains Enoxaparin, which is low molecular weight heparin or LMWH. It helps to treat harmful blood clots that are in your blood. Besides, this Cloti-XA 40 mg/0.4 ml Injection 1's can stop blood clots due to several medical conditions, including unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and blood clots forming in the tubes of your dialysis machine. Cloti-XA 40 mg/0.4 ml Injection 1's works by stopping existing blood clots from getting any bigger; this helps your body to break them down and prevents them from causing you harm. On the other hand, it stops new blood clots from forming in your blood.

Directions for Use

Cloti-XA 40 mg/0.4 ml Injection 1's will be administered by a qualified healthcare professional. Kindly do not self-administer.

Side Effects of Cloti-XA 40 mg/0.4 ml Injection 1's

  • Bleeding
  • Increases in liver enzymes
  • Bruise more easily than usual
  • Pink patches on your skin 
  • Skin rash (hives, urticaria)
  • Itchy red skin
  • Bruising or pain at the injection site
  • Decreased red blood cell count
  • High platelet counts in the blood
  • Headache

Drug Warnings

Patients should inform the doctor if they are on active treatment with this Cloti-XA 40 mg/0.4 ml Injection 1's before any surgery is scheduled. If you are known to be allergic to Cloti-XA 40 mg/0.4 ml Injection 1's or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using the Cloti-XA 40 mg/0.4 ml Injection 1's. Before using this Cloti-XA 40 mg/0.4 ml Injection 1's, disclose to your doctor if you have any pre-existing medical conditions like stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders, And also let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Drug-Drug Interactions

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EnoxaparinDefibrotide
Critical

Drug-Drug Interactions

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How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Combining Mifepristone with Cloti-XA 40 mg/0.4 ml Injection can increase the risk or severity of side effects of vaginal bleeding.

How to manage the interaction:
Taking Cloti-XA 40 mg/0.4 ml Injection with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience prolonged, excessive bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EnoxaparinDefibrotide
Critical
How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Combining Defibrotide with Cloti-XA 40 mg/0.4 ml Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Cloti-XA 40 mg/0.4 ml Injection with Defibrotide is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Coadministration of Apixaban and Cloti-XA 40 mg/0.4 ml Injection co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Cloti-XA 40 mg/0.4 ml Injection and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Taking Cloti-XA 40 mg/0.4 ml Injection and ketorolac together can increase the risk or severity of bleeding problems.

How to manage the interaction:
Although taking Ketorolac and Cloti-XA 40 mg/0.4 ml Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Co-administration of Prasugrel with Cloti-XA 40 mg/0.4 ml Injection can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Prasugrel and Cloti-XA 40 mg/0.4 ml Injection, you can take them if advised by a doctor. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor. Do not stop using any medications without a doctor's advice.
EnoxaparinSulindac
Severe
How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Taking Sulindac with Cloti-XA 40 mg/0.4 ml Injection can increase the risk or severity of bleeding.

How to manage the interaction:
Coadministration of Cloti-XA 40 mg/0.4 ml Injection with Sulindac can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs of difficulty with bleeding, bleeding, bruising, swelling, throwing up, headache, feeling lightheaded, weakness, or seeing blood in your urine or stools, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Coadministration of Warfarin with Cloti-XA 40 mg/0.4 ml Injection can increase the risk or severity of bledding.

How to manage the interaction:
There may be a possible interaction between Cloti-XA 40 mg/0.4 ml Injection and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Taking Urokinase with Cloti-XA 40 mg/0.4 ml Injection can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Cloti-XA 40 mg/0.4 ml Injection and Urokinase, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like bleeding, bruising, dizziness, black or tarry stools, weakness, vomiting, or headaches, it is important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Co-administration of Meloxicam with Cloti-XA 40 mg/0.4 ml Injection together can increase the risk or severity of bleeding.

How to manage the interaction:
Although taking Meloxicam and Cloti-XA 40 mg/0.4 ml Injection together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like bleeding, bruising, swelling, vomiting, headache, dizziness, weakness, or blood in your urine or stool, contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cloti-XA 40 mg/0.4 ml Injection:
Taking Heparin with Cloti-XA 40 mg/0.4 ml Injection may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Heparin and Cloti-XA 40 mg/0.4 ml Injection, but it can be taken if prescribed by a doctor. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • HEPARIN
  • WARFARIN
  • RIVAROXABAN
  • DEXTRAN INJECTION
  • PREDNISOLONE
  • DEXAMETHASONE

Habit Forming

No

Special Advise

Regular blood tests are advised while taking Cloti-XA 40 mg/0.4 ml Injection 1's to monitor prothrombin, platelets, and coagulation time on a regular basis.

Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime complement treatment with Cloti-XA 40 mg/0.4 ml Injection 1's effectively.
  • As a precautionary measure, you are recommended not to consume alcohol, or junk food items from outside, stick to a freshly prepared home-cooked meal and rest properly for a speedy recovery.
  • And also, trying to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL in a short time.
  • Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Option for foods high in vitamin K (liver, leafy green vegetables, or vegetable oils) as Cloti-XA 40 mg/0.4 ml Injection 1's may lower Vitamin K in your body.
  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.
  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Cloti-XA 40 mg/0.4 ml Injection 1's and lead to unwanted side effects. Hence try to avoid these juices while taking Cloti-XA 40 mg/0.4 ml Injection 1's.

Cloti-XA 40 mg/0.4 ml Injection 1's Substitute

Always consult your doctor before taking any new medications and supplements

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