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Written By ,
Reviewed By Sunny S , MBBS
48 Hrs returnable
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Manufacturer/Marketer :

Parasol Laboratories

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANALGESICS

Country of origin

India
Other Info - CO32682

FAQs

Yes, Coflam MR 400mg/325mg/250mg Tablet is known to cause dizziness. If you feel dizzy, please take rest and also avoid driving while you take Coflam MR 400mg/325mg/250mg Tablet as it can be harmful.

Coflam MR 400mg/325mg/250mg Tablet when taken by patients who are allergic to pain-killers or NSAIDs can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.

Yes. But ensure pain killers or any other drugs you are taking does not contain paracetamol, aceclofenac or chlorzoxazone. As, it may lead to overdosage leading to unpleasant side effects.

Taking excessive alcohol with Coflam MR 400mg/325mg/250mg Tablet can cause liver damage. So, it is advisable to avoid or limit intake of alcohol during the treatment with Coflam MR 400mg/325mg/250mg Tablet.

It depends on whether your cough and cold pills contain ibuprofen, chlorzoxazone and paracetamol or not. If it contains these two medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.

Coflam MR 400mg/325mg/250mg Tablet is known to be contra-indicated in patients allergic to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of heart failure, high blood pressure, stomach ulcer and kidney/liver disease.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Taking Coflam MR 400mg/325mg/250mg Tablet with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages with Coflam MR 400mg/325mg/250mg Tablet.

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Pregnancy

Unsafe

Use of Coflam MR 400mg/325mg/250mg Tablet during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby.

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Breast Feeding

Caution

Take Coflam MR 400mg/325mg/250mg Tablet only if prescribed by your doctor.

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Driving

Unsafe

After taking Coflam MR 400mg/325mg/250mg Tablet you may notice dizziness, sleepiness, drowsiness or fatigue as it contain paracetamol which causes sedation. So, in this you should stop taking Coflam MR 400mg/325mg/250mg Tablet and contact your doctor.

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Liver

Caution

Coflam MR 400mg/325mg/250mg Tablet to be taken with caution, especially if you have a history of liver disease. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Coflam MR 400mg/325mg/250mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Coflam MR 400mg/325mg/250mg Tablet is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated. It should be use only when prescribed by a child specialist.

About Coflam MR 400mg/325mg/250mg Tablet

Coflam MR 400mg/325mg/250mg Tablet belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). Coflam MR 400mg/325mg/250mg Tablet is used in the reduction of musculoskeletal pain and muscle spasm due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). Pain can be temporary (acute) or long term (chronic) in nature. Musculoskeletal pain can be caused due to soft tissues (muscle, tendon or ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

Coflam MR 400mg/325mg/250mg Tablet contains Ibuprofen, Paracetamol and Chlorzoxazone. Ibuprofen is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of Ibuprofen. Chlorzoxazone is a muscle relaxant, helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Take Coflam MR 400mg/325mg/250mg Tablet as prescribed. Like all medicines, Coflam MR 400mg/325mg/250mg Tablet may cause side effects, although not everybody gets them. Nausea, indigestion,  diarrhoea, drowsiness, dizziness, heartburn, stomach pain and restlessness are a few common side effects of Coflam MR 400mg/325mg/250mg Tablet.

Do not take Coflam MR 400mg/325mg/250mg Tablet if you are allergic to painkillers like aspirin, paracetamol, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Coflam MR 400mg/325mg/250mg Tablet may be associated with a small increase in the risk of heart attack (myocardial infarction). Avoid consumption of alcohol as it may damage your liver and cause even more side effects on taking this drug. Consult your doctor if your symptoms of pain, inflammation and fever do not disappear even after ten days.

Uses of Coflam MR 400mg/325mg/250mg Tablet

Musculoskeletal pain, Muscle spasm.

Medicinal Benefits Mweb

Medicinal Benefits

Coflam MR 400mg/325mg/250mg Tablet is composed of ibuprofen, chlorzoxazone and paracetamol primarily used to treat mild to moderate pain. Coflam MR 400mg/325mg/250mg Tablet plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers which cause pain and fever. Coflam MR 400mg/325mg/250mg Tablet relieves pain and inflammation in arthritic conditions with benefit of increased antibiotic penetration and micro-circulation at the injury site. Ibuprofen works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Paracetamol has the advantage of producing lesser gastric irritation compared to other painkillers like aspirin. So, it is well tolerated in mostly all age groups. Chlorzoxazone benefits in relaxing muscle to treat any type of musculoskeletal conditions like sprain, pain or injury. It is mainly prescribed for the sports related injury. Overall it relieve muscle spasm or stiffness of musculoskeletal joints thereby improving its movement.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Coflam MR 400mg/325mg/250mg Tablet

  • Nausea
  • Indigestion
  • Diarrhoea
  • Drowsiness
  • Dizziness
  • Heartburn
  • Stomach pain
  • Restlessness

Drug Warnings

Coflam MR 400mg/325mg/250mg Tablet should be taken with caution if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent by-pass heart surgery, heart disease or history of allergy to any painkillers or analgesic. Avoid driving while consuming Coflam MR 400mg/325mg/250mg Tablet as it can cause dizziness in some individuals and hamper your focus and reflexes. Avoid concomitant consumption of drugs containing the same chemicals as Coflam MR 400mg/325mg/250mg Tablet as it can lead to overdosage and unwanted side effects. Immediately consult your doctor in case of persistent side effects like stomach pain on consumption of Coflam MR 400mg/325mg/250mg Tablet. Avoid consuming alcohol while you are on Coflam MR 400mg/325mg/250mg Tablet.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Taking Ketorolac and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac and Coflam MR 400mg/325mg/250mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Combining Meloxicam and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Meloxicam and Coflam MR 400mg/325mg/250mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
ChlorzoxazoneMorphine
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Using Morphine together with Coflam MR 400mg/325mg/250mg Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Coflam MR 400mg/325mg/250mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ChlorzoxazoneTapentadol
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Taking Tapentadol with Coflam MR 400mg/325mg/250mg Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Coflam MR 400mg/325mg/250mg Tablet with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Co-administration of Prasugrel and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenFenoprofen
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
The combined use of Fenoprofen and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Fenoprofen and Coflam MR 400mg/325mg/250mg Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising,dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Coadministration of Lithium and Coflam MR 400mg/325mg/250mg Tablet can increases the blood levels of Lithium.

How to manage the interaction:
Co-administration of Lithium and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like drowsiness, dizziness, confusion, diarrhea, vomiting, muscle weakness, muscle inco-ordination, tremor, blurred vision, ringing in the ear, excessive thirst, and increased urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMetrizamide
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
The combined use of Metrizamide and Coflam MR 400mg/325mg/250mg Tablet can cause kidney damage.

How to manage the interaction:
Co-administration of Metrizamide and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Co-administration of Prednisolone and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects of each other.

How to manage the interaction:
A combination of Prednisolone and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
IbuprofenDanaparoid
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
The combined use of Danaparoid and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of bleeding complications.

How to manage the interaction:
Taking Danaparoid and Coflam MR 400mg/325mg/250mg Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness during treatment with these medications, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • NAPROXEN
  • ASPIRIN
  • IBUPROFEN
  • TRAMADOL
  • HYDROCODONE
  • OXYCODONE
  • LITHIUM
  • METHOTREXATE
  • WARFARIN
  • COUMADIN
  • JANTOVEN
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • FUROSEMIDE
  • PREDNISONE
  • CIPROFLOXACIN
  • THEOPHYLLINE
  • EPHEDRINE
  • CHOLESTYRAMINE
  • DULOXETINE

Habit Forming

No

Special Advise

Stop using Coflam MR 400mg/325mg/250mg Tablet and consult your doctor immediately if you are having bleeding from the rectum (back passage), have black sticky bowel motions (stools) or bloody diarrhoea.

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, calcium enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • In chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long term immobility is harmful in conditions like arthritis.  Use back support like a rolled up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a foot rest if required.

Coflam MR 400mg/325mg/250mg Tablet Substitute

Always consult your doctor before taking any new medications and supplements

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